Neely Williams
A5025680920- Bariatric Surgery and Outcomes
- Long-Term Effects of COVID-19
- Obesity and Health Practices
- Health Policy Implementation Science
- COVID-19 Clinical Research Studies
- Body Contouring and Surgery
- Health and Medical Research Impacts
- Health Sciences Research and Education
- Diet and metabolism studies
- SARS-CoV-2 and COVID-19 Research
- Patient Satisfaction in Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health and Patient Involvement
- Ethics in Clinical Research
- Patient-Provider Communication in Healthcare
- COVID-19 and healthcare impacts
- Musculoskeletal pain and rehabilitation
- Primary Care and Health Outcomes
- Thermal Regulation in Medicine
- Sepsis Diagnosis and Treatment
- Healthcare Systems and Technology
- Social Media in Health Education
- Empathy and Medical Education
- Lung Cancer Diagnosis and Treatment
- COVID-19 and Mental Health
Community Partners
2013-2024
Universitat de Barcelona
2022
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2022
Hospital Clínic de Barcelona
2021-2022
Research Network (United States)
2020
Vanderbilt University Medical Center
2015-2020
Vanderbilt University
2015-2018
Kaiser Permanente
2016
Meharry Medical College
2015
National Center for Advancing Translational Sciences
2015
Background: There has been a dramatic shift in use of bariatric procedures, but little is known about their long-term comparative effectiveness. Objective: To compare weight loss and safety among procedures. Design: Retrospective observational cohort study, January 2005 to September 2015. (ClinicalTrials.gov: NCT02741674) Setting: 41 health systems the National Patient-Centered Clinical Research Network. Participants: 65 093 patients aged 20 79 years with body mass index (BMI) 35 kg/m2 or...
Engaging communities in research increases its relevance and may speed the translation of discoveries into improved health outcomes. Many researchers lack training to effectively engage stakeholders, whereas academic institutions infrastructure support community engagement.In 2009, Meharry-Vanderbilt Community-Engaged Research Core began testing new approaches for engagement, which led development Community Engagement Studio (CE Studio). This structured program facilitates project-specific...
Bariatric surgery can lead to substantial improvements in type 2 diabetes (T2DM), but outcomes vary across procedures and populations. It is unclear which bariatric procedure has the most benefits for patients with T2DM.To evaluate associations of T2DM outcomes.This cohort study was conducted 34 US health system sites National Patient-Centered Clinical Research Network Study. Adult who had between January 1, 2005, September 30, 2015, were included. Data analysis from April 2017 August...
ObjectiveTo describe PCORnet, a clinical research network developed for patient-centered outcomes on national scale.Study Design and SettingDescriptive study of the current state future directions PCORnet. We conducted cross-sectional analyses health systems patient populations 9 Clinical Research Networks 2 Health Plan that are part PCORnet.ResultsWithin Networks, electronic data currently collected from 337 hospitals, 169,695 physicians, 3,564 primary care practices, 338 emergency...
Additional data comparing longer-term problems associated with various bariatric surgical procedures are needed for shared decision-making.To compare the risks of intervention, operation, endoscopy, hospitalization, and mortality up to 5 years after 2 procedures.Adults who underwent Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) between January 1, 2005, September 30, 2015, within National Patient-Centered Clinical Research Network. Data from 33 560 adults at 10 centers 4 clinical...
<h2>Abstract</h2><h3>Background</h3> Bariatric surgery has been used for treatment of severe obesity in adolescents but most studies have small and limited follow-up. <h3>Objectives</h3> We hypothesized that electronic health record data could be to compare effectiveness bariatric procedures adolescents. <h3>Setting</h3> Data were obtained from clinical research networks using a common model extract each site. <h3>Methods</h3> Adolescents who underwent primary procedure 2005 through 2015...
Abstract Whether initiation of statins could increase survival free dementia and disability in adults aged ≥75 years is unknown. PREVENTABLE, a double‐blind, placebo‐controlled randomized pragmatic clinical trial, will compare high‐intensity statin therapy (atorvastatin 40 mg) with placebo 20,000 community‐dwelling without cardiovascular disease, disability, or at baseline. Exclusion criteria include use the prior year for >5 inability to take statin. Potential participants are identified...
There are currently no validated clinical biomarkers of postacute sequelae SARS-CoV-2 infection (PASC).
Abstract Background The use of remdesivir has demonstrated a significant reduction in the time to recovery patients with COVID-19. However, impact on mortality is still controversial. Therefore, it necessary evaluate whether there specific subgroup whom an active antiviral therapy also reduces mortality. Methods Patients admitted for &gt;48 h our hospital SARS-CoV-2 confirmed or suspected infection from February 2020 2021 were retrospectively analysed. primary outcome study was at 30...
Although bariatric procedures are commonly performed in clinical practice, long-term data on the comparative effectiveness and safety of different sustained weight loss, comorbidities, adverse effects limited, especially important patient subgroups (eg, individuals with diabetes, older patients, adolescents, minority patients).The objective this study was to create a population-based cohort patients who underwent 3 procedures-adjustable gastric band (AGB), Roux-en-Y bypass (RYGB), sleeve...
Bariatric surgery is the most effective treatment for severe obesity; yet it unclear whether long-term safety and comparative effectiveness of these operations differ across racial ethnic groups.To compare outcomes Roux-en-Y gastric bypass (RYGB) sleeve gastrectomy (SG) groups in National Patient-Centered Clinical Research Network (PCORnet) Study.This was a retrospective, observational, cohort study that comprised 25 health care systems PCORnet Study. Patients were adults adolescents aged 12...
Abstract Objectives To understand the formal roles of community representatives (CRs) in Clinical and Translational Science Awardee (CTSA) activities, to evaluate extent integration into organizational governance structures identify barriers effective integration. Methods The inventory tool was distributed each 60 CTSAs using a secure web application. Results Forty‐seven (78%) completed inventory. mean number CRs per CTSA is 21.4 (SD: 14.8). Most had advisory boards (89%) 94% included...
To ensure meaningful engagement of stakeholders (patients, clinicians, and communities) in developing the Mid-South Clinical Data Research Network (MS-CDRN), we implemented a comprehensive, multilevel approach: (1) identify barriers to involving governance, network design, implementation; (2) engage priority setting research topic generation; (3) develop strategies fully integrate CDRN governance oversight; (4) solicit guidance on patient-centered tools for recruiting participants.We engaged...
Abstract Objective Prior research suggests shared decision‐making (SDM) could improve patient and health care provider communication about bariatric surgery. The aim of this work was to identify prioritize barriers SDM around surgery help guide implementation SDM. Methods Two large US systems formed multidisciplinary teams facilitate the used a nominal group process approach involving (1) generation multilevel barriers, (2) round‐robin recording (3) facilitated discussion, (4) selection...
Background: Engaging communities in research is increasingly recognized as critical to translation of into improved health outcomes. Our objective was understand community stakeholders' perspectives on researchers, academic institutions, and how valued research.
Dissemination of results to research participants is largely missing from the practices most researchers. Few resources exist that describe best for disseminating information this important stakeholder group.Four focus groups were conducted with a diverse group individuals. All part Patient-Centered Outcomes Research Institute-funded survey study. Focus aimed identify participants' preferences about receiving and their reactions three different dissemination platforms.Four 37 conducted,...
Abstract Dexamethasone and tocilizumab have been associated with reduction in mortality, however, the beneficial effect is not for all patients impact on viral replication well defined. We hypostatized that C-reactive protein (CRP) could help identification of requiring anti-inflammatory therapy. Patients admitted > 48 h our hospital a confirmed or suspected infection by SARS-CoV-2 from February 2020 to 2021 were retrospectively evaluated. The primary outcome was mortality at 30 days....
Amid increasing interest in improving the patient-centeredness of research, new forms engagement are emerging that enable researchers to get input from community members on research goals, methods, and implementation. This often includes stories, which useful for understanding lived experiences illness encounters with health care organizations, locating these within larger meta-narratives specific communities. We analyzed stories transcripts 13 Community Engagement Studios identified 4 major...
Abstract Background The evidence based on the inclusion of patients and other stakeholders as partners in clinical research process has grown substantially. However, little been reported how are engaged governance large‐scale networks infrastructure used by to support engagement network‐affiliated activities. Objectives objective was document activities practices emerging from Clinical Research Networks (CRNs) participating PCORnet, National Patient‐Centered Network, specifically regarding...