A5015277592- Systemic Lupus Erythematosus Research
- Frailty in Older Adults
- Vasculitis and related conditions
- Health Systems, Economic Evaluations, Quality of Life
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical Practices and Patient Outcomes
- COVID-19 Clinical Research Studies
- Nutrition and Health in Aging
- Chronic Disease Management Strategies
- Long-Term Effects of COVID-19
- Global Cancer Incidence and Screening
- Bone health and osteoporosis research
- Balance, Gait, and Falls Prevention
- COVID-19 and healthcare impacts
- Colorectal Cancer Screening and Detection
- Systemic Sclerosis and Related Diseases
- Blood Pressure and Hypertension Studies
- Hip and Femur Fractures
- Body Composition Measurement Techniques
- Healthcare cost, quality, practices
- Emergency and Acute Care Studies
- Geriatric Care and Nursing Homes
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- SARS-CoV-2 and COVID-19 Research
- Cardiac, Anesthesia and Surgical Outcomes
Hospital Clínic de Barcelona
2013-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2015-2025
Universitat de Barcelona
2015-2025
General Department of Preventive Medicine
2024
Fundació Clínic per a la Recerca Biomèdica
2023
Hospital Plató
2022
Weatherford College
2021
Spanish Society of Family and Community Medicine
2014-2016
Services Hospital
2008
A prospective two dimensional and Doppler echocardiographic study of 70 consecutive patients with systemic lupus erythematosus (SLE) 40 controls was carried out. Forty (57%) were found to have disturbance. Valvular abnormalities detected in 31 (44%) only (5%). Mitral valve the most common findings (23/70 (33%)) mild or moderate regurgitation frequent lesion (16% 9% respectively). Three (4%) had a morphological pattern suggestive non-infective verrucous vegetations affecting mitral valve. No...
Abstract Introduction Long-term outcomes of elderly patients after medical ICU care are little known. The aim the study was to evaluate functional status and quality life 12 months discharge from a ICU. Methods We prospectively studied 112/230 healthy (≥65 years surviving at least discharge) with full autonomy without cognitive impairment prior entry. main diagnoses admission using Acute Physiology Chronic Health Evaluation III (APACHE III) classification diagnosis length stay scores II,...
The purpose of this study was to evaluate the prevalence sarcopenia in a cohort healthy community-dwelling elderly an urban area Barcelona (Spain) for native benchmarks and compare them with those published other geographical areas.
To assess whether the intensity of initial systemic inflammatory response is able to predict therapy in patients with giant cell arteritis (GCA).Retrospective review 75 (49 women and 26 men) biopsy-proven GCA who had regular followup were treated according uniform criteria. Four parameters used evaluate baseline at diagnosis: fever, weight loss, erythrocyte sedimentation rate > or = 85 mm/hour, hemoglobin < 110 gm/liter. Patients considered have a weak if they 2 fewer (group 1) strong 3 4...
Systemic lupus erythematosus (SLE) predominantly affects young women in their 20s. In 40 out of 250 (16%) patients with SLE seen our hospital disease onset occurred after the age 50. The interval between time and diagnosis was five years this older group compared three younger group. Arthritis, as a first symptom, less common During follow up lower incidence arthritis, malar rash, photosensitivity, nephropathy found contrast, showed an increased myositis. High titres anti-dsDNA tended to...
Genetic alterations in Ca<sup>2+</sup> channel subunits can be used to study the interaction among and their roles function. P/Q- N-type channels reside at presynaptic terminal control release of neurotransmitter mammalian central synapses. We fluorescence imaging techniques investigate Ca<sup>2+</sup>currents hippocampal Schaffer collateral synapses both <i>tottering</i>(<i>tg</i>, α<sub>1A</sub> subunit) and<i>lethargic</i> (<i>lh</i>, β<sub>4</sub> mutant mice. Application selective...
Scientific evidence on treatments of chronic diseases in patients 85 years old or older is very limited, as available information inappropriate prescription (IP) and its associated factors. The study aimed to describe medicine prescription, potentially medicines (PIM) prescribing omissions (PPO) their factors this population. In the context an observational, prospective multicentric carried out elderly admitted seven Spanish hospitals for a year, sub-analysis those aged over was performed....
Abstract Background The use of remdesivir has demonstrated a significant reduction in the time to recovery patients with COVID-19. However, impact on mortality is still controversial. Therefore, it necessary evaluate whether there specific subgroup whom an active antiviral therapy also reduces mortality. Methods Patients admitted for &gt;48 h our hospital SARS-CoV-2 confirmed or suspected infection from February 2020 2021 were retrospectively analysed. primary outcome study was at 30...
<i>Background:</i> Cecal ligation and puncture is a widely used experimental model of sepsis. <i>Aim the Study:</i> The present study was aimed to evaluate influence size cecal on mortality, bacteremia, endotoxemia plasma TNF-α levels. <i>Materials Methods:</i> Female Sprague-Dawley rats underwent puncture, divided into following groups, defined by diameter puncture: 0.5-cm blade incision (n = 25), 13-gauge 16-gauge 18-gauge 25) 4 punctures with 22-gauge...
Pregnancy loss, often recurrent, is one of the most important clinical manifestations associated with primary antiphospholipid syndrome. In these cases, pregnancy wastage related to presence antibodies, namely lupus anticoagulant and anticardiolipin but patients do not have features systemic erythematosus or any other well-defined autoimmune disease. We report here on outcome 21 consecutive pregnancies in 18 syndrome who were treated low-dose aspirin (100 mg/day) from 1 month before...
Although systemic lupus erythematosus (SLE) has traditionally been considered a disease of women, men may also be affected. Thirty 261 patients (12%) with SLE seen in this hospital were men. Arthritis was less common as first symptom the men, although group had discoid lesions and serositis more often than women. During follow up lower incidence arthritis malar rash higher other skin complications including subcutaneous found The nephropathy, neurological disease, thrombocytopenia,...
Cancer may be diagnosed in advanced stages, when the patient has already developed metastasis, with symptoms that can also observed benign diseases. The objective of this study was to evaluate tumor marker sensitivity and specificity differential diagnosis patients suspected signs cancer. We studied 2.711 consecutive admitted Internal Medicine Department our hospital cancer; 1.240 had non-malignant processes 1.471 malignant disease. Determinations were considered positive for malignancy...
Abstract Aims To assess inappropriate prescribing in older people with diabetes mellitus during the month prior to a hospitalization, using tools on potentially medicines ( PIM s) and potential omissions PPO comparing patients without diabetes. Methods In an observational, prospective multicentric study, we assessed 672 aged 75 years hospital admission. The Beers, Screening Tool of Older Person's Prescriptions STOPP ) Alert Doctors Right Treatment START criteria Assessing Care Vulnerable...
Spain has an advanced, integrated health care system that achieved remarkable results, including substantially improved outcomes, over a relatively short time. Measures introduced by central and regional governments to combat the financial crisis may be severely affecting sector, with proposed changes potentially threatening principles of equity social cohesion underlying welfare state. This article examines recent developments in Spanish care, focusing on austerity measures since 2010. In...