MRI has been employed to elucidate the migratory behavior of stem/progenitor cells noninvasively in vivo with traditional proton (1H) imaging iron oxide nanoparticle-labeled cells. Alternatively, we demonstrate that fluorine (19F) labeled different types liquid perfluorocarbon (PFC) nanoparticles produces unique and sensitive cell markers distinct from any tissue background signal. To define utility for tracking, mononuclear harvested human umbilical cord blood were grown under...

Objective Cochlear nerve deficiency (CND) is increasingly diagnosed in children with sensorineural hearing loss (SNHL). We sought to determine the prevalence of CND, its imaging characteristics, and correlations audiologic phenotype unilateral SNHL. Design Case series chart review. Setting Tertiary pediatric hospital. Subjects/Methods In 128 consecutive SNHL who underwent high‐resolution magnetic resonance imaging, diameters, area, signal intensity cochlear (CN) were measured normalized...

Abstract Objective To compare surgical and nonsurgical definitive treatment in cT4b major salivary gland cancer (MSGC). Study Design Retrospective cohort study. Setting The 2004 to 2019 National Cancer Database. Methods NCDB was queried for patients with MSGC (N = 976). Patients undergoing (1) resection + adjuvant therapy, (2) radiotherapy (RT) alone, or (3) chemoradiotherapy (CRT) were included Kaplan‐Meier Cox survival analyses. Results Of 219 treatment, 148 (67.6%) underwent therapy 71...

Background The purpose of this article was to assess the rates head and neck free tissue transfer variables available in American College Surgeons – National Surgical Quality Improvement Project (ACS–NSQIP) dataset predict overall serious complications. Methods We conducted a data analysis from 2005 2014 on cases with descriptive cross-sectional examine correlation NSQIP complications (p < .05). Results Of 1643 flaps, 906 occurred, such as blood transfusion, return operating room, extended...

Unplanned hospital readmission is costly and in recent years has become a focus of health care legislation intended to reduce expenditures. Greater understanding which perioperative complications are associated with after surgery for head neck cancer needed unplanned readmissions.To determine clinical risk factors 30-day malignant neoplasms the neck.This retrospective longitudinal claims analysis included data from American College Surgeons National Surgical Quality Improvement Program...

Objective Undergoing surgery and adjuvant radiotherapy (aRT) at the same facility has been associated with higher overall survival (OS) in head neck squamous cell carcinoma. Our study investigates whether undergoing aRT academic is OS major salivary gland cancer (MSGC). Methods The 2006–2018 National Cancer Database was queried for patients MSGC an then aRT. Multivariable binary logistic Cox proportional hazards regression models were implemented. Results Of 2801 satisfying inclusion...

Objectives/Hypothesis To identify relevant patient and surgical risk factors associated with prolonged length of stay, return to the operating room, readmission within 30 days following total laryngectomy using American College Surgeons National Quality Improvement Program (ACS-NSQIP) Study Design Retrospective database study. Patients undergoing alone for laryngeal cancer were identified from ACS-NSQIP 2005 2014. Methods Multivariate logistic regression was used independent predictors...

<h3>Importance</h3> Patients with head and neck cancer receive care at academic comprehensive programs (ACCPs), integrated network (INCPs), community (CCCPs), (CCPs). The type of treatment facility may be associated overall survival. <h3>Objective</h3> To examine whether is survival after a diagnosis cancer. <h3>Design, Setting, Participants</h3> This population-based retrospective cohort study included patients from the National Cancer Database, prospectively maintained, hospital-based...

Abstract Objective To investigate the survival benefit of elective neck dissection (END) over observation in surgically resected cT1‐4 N0M0 head and basaloid carcinoma (HNBC). Study Design Retrospective cohort study. Setting The 2006 to 2017 hospital‐based National Cancer Database. Methods Patients with HNBC were selected. Linear, binary logistic, Kaplan‐Meier, Cox proportional hazards regression models implemented. Results Of 857 patients satisfying inclusion criteria, majority male (77.0%)...

Esthesioneuroblastomas (ENB) are uncommon and data regarding outcomes often limited to single-institution series. The National Cancer Database (NCDB), which contains information from treatment centers across the United States, represents an opportunity evaluate for rare diseases such as ENB multiple institutions.The NCDB was queried location codes corresponding nasal cavity paranasal sinuses histology code ENB. Multivariate analyses were performed contributing factors overall survival.A...

Prolonged hospitalization and reoperation after free tissue transfer may be associated with certain clinical factors.To determine patient surgical factors length of stay (LOS) following procedures for malignant neoplasm the head neck involving microvascular reconstruction.This was a retrospective review American College Surgeons National Surgical Quality Improvement Program data from 2012 to 2014 using International Classification Diseases, Ninth Revision (ICD-9), codes neoplasms neck....

Abstract Background To develop machine learning (ML) models predicting unplanned readmission and reoperation among patients undergoing free flap reconstruction for head neck (HN) surgery. Methods Data were extracted from the 2012–2019 NSQIP database. eXtreme Gradient Boosting (XGBoost) was used to ML 30‐day based on demographic perioperative factors. Models validated using 2019 data evaluated. Results Four‐hundred sixty‐six (10.7%) of 4333 included readmitted within 30 days initial The model...

To investigate primary site surgical resection and overall survival (OS) in clinically distantly metastatic (cM1) oral cavity squamous cell carcinoma (OCSCC).

Objective To survey patients following sinonasal surgery regarding postoperative pain and opioid use. Study Design Patients were surveyed for 4 days sinus and/or nasal their level use of prescribed opioids. Setting Four academic medical centers 1 private practice institution. Subjects Consecutive adult undergoing surgery. Results A total 219 subjects met criteria included analysis; 134 (61%) took 5 or fewer combination oxycodone (5‐mg) acetaminophen (325‐mg) tablets in the first 3 days, 196...

To investigate national trends in admission status after thyroidectomy the United States and to evaluate factors associated with 30-day unplanned readmission reoperation.Retrospective review of American College Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) METHODS: The ACS-NSQIP database was queried for patients who underwent a partial or total between 2005 2014. Outpatient surgery defined as discharge on day surgery. Patient demographic information, hospital...

A better understanding of the natural history vestibular schwannoma (VS) has resulted in a change treatment paradigms. It also been proposed that increased use high-resolution magnetic resonance imaging allowed for an identification small tumors. The aim this study was to evaluate recent trends presentation and primary management VS United States.Retrospective analysis National Cancer Database (NCDB).NCDB database.All patients with diagnosis between 2004 2014 were included. Data analyzed...

Abstract Vestibular schwannomas (VS) are the most common tumor of skull base with available treatment options that carry a risk iatrogenic injury to facial nerve, which can significantly impact patients’ quality life. As nerve outcomes remain challenging prognosticate, we endeavored utilize machine learning decipher predictive factors relevant following microsurgical resection VS. A database patient-, tumor- and surgery-specific features was constructed via retrospective chart review 242...

ABSTRACT Objective Hypoalbuminemia (HA) is a proxy for malnutrition that has been associated with postoperative complications in several surgical subspecialties. This study investigates the association between pre‐operative HA and following major salivary gland (MSG) resection. Methods Patients undergoing outpatient, elective MSG resection were extracted from 2005 to 2020 National Surgical Quality Improvement Program database. Demographics comorbidities compared (preoperative serum albumin...

<title>Abstract</title> Objectives Tumor factors such as subsite and stage impact the risk of lymph node metastasis (LNM) overall in sinonasal squamous cell carcinoma (SNSCC). We sought to identify rates patients presenting with or without clinical LNM for different tumor subsites stages surgically-treated SNSCC, determine concordance between pathologic after neck dissection (ND), predictors occult LNM. Methods The National Cancer Database was queried SNSCC from 2004–2016. For LNM,...

Abstract Objective To investigate the survival benefit of elective neck dissection (END) over observation in surgically resected cT1‐4 N0M0 head and spindle cell carcinoma (HNSpCC). Study Design Retrospective cohort study. Setting The 2006 to 2018 hospital‐based National Cancer Database (NCDB). Methods Patients with HNSpCC were selected. Linear, binary logistic, Kaplan‐Meier, Cox proportional hazards regression models implemented. Results Of 815 patients satisfying inclusion criteria, a high...

The transfemoral approach has traditionally been the primary access site for catheter-guided venography. Recently, upper extremity transvenous (UETV) emerged as a promising alternative neurointerventional procedures, offering potential advantages such reduced bleeding risk, improved ergonomics, faster recovery, shorter procedure and fluoroscopy times, lower likelihood of inadvertent arterial puncture. This study reports on single-center experience UETV venous therapy. A total 158 diagnostic...