A5006553768- Antibiotic Resistance in Bacteria
- Bacteriophages and microbial interactions
- Pharmaceutical and Antibiotic Environmental Impacts
- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Genomics and Phylogenetic Studies
- Mycobacterium research and diagnosis
- Supercapacitor Materials and Fabrication
- Enterobacteriaceae and Cronobacter Research
- Microbial Natural Products and Biosynthesis
- Vibrio bacteria research studies
- Aquaculture disease management and microbiota
- Antimicrobial Resistance in Staphylococcus
- Bacterial Genetics and Biotechnology
- Clostridium difficile and Clostridium perfringens research
- Cancer Research and Treatments
- Gut microbiota and health
- Listeria monocytogenes in Food Safety
- Probiotics and Fermented Foods
- CRISPR and Genetic Engineering
- Advanced battery technologies research
- Microbial Metabolism and Applications
- Viral gastroenteritis research and epidemiology
- Veterinary medicine and infectious diseases
- Mycotoxins in Agriculture and Food
Fudan University
2014-2025
ZheJiang Academy of Agricultural Sciences
2016-2025
Chinese Academy of Sciences
2011-2025
University of Chinese Academy of Sciences
2013-2025
First Affiliated Hospital of Wannan Medical College
2015-2025
China University of Mining and Technology
2023-2024
Southwest University
2024
Jiamusi University
2024
Lanzhou Jiaotong University
2024
Wuhan Polytechnic University
2024
Antimicrobial-resistant Salmonella enterica poses a significant public health concern worldwide. However, the dissemination of among food animals in eastern China has not been fully addressed. Here, we demonstrated antimicrobial resistance (AMR) patterns and whole-genome characterization 105 S. isolates from 1,480 fecal samples anal swabs collected 22 different farms (chickens, ducks, pigs) two live animal markets located Zhejiang Fujian Provinces 2019. The prevalence duck (19.17%, 23/120)...
Non-pharmaceutical interventions (NPIs) have been proven effective in reducing the spread of coronavirus disease 2019 (COVID-19), but their broader impact on gastrointestinal disorders remains poorly studied. Here, we report an observational analysis and retrospective study that compares incidence acute diarrheal diseases Hangzhou, Zhejiang, China, between 2020, with examination antimicrobial resistance genetic spectrum non-typhoidal Salmonella (NTS) from 2015 to 2022, before during COVID-19...
Antibiotics are widely used in the treatment of bacterial infections and as food additives livestock industry. The wide usage antibiotics causes residues animal products, like milk, eggs meat. A number studies have reported that antibiotic exist at high concentrations watercourses around world. Doxycycline (DH), oxytetracycline (OTCC) florfenicol (FF) three most commonly veterinary China. However, toxic effects DH, OTCC FF limited. In this study, six-moth-old healthy male adult zebrafish...
A total of 1,400 samples food animals (pigs, chickens, and ducks) were collected between July September 2019 in China to uncover the prevalence E. fergusonii its potential role evolution antimicrobial resistance (AMR). An isolation was performed pulsed-field gel electrophoresis (PFGE) used genetic relationship. The AMR isolates comprehensively characterized using broth microdilution-based susceptibility testing, S1-PFGE, southern hybridization, whole-genome sequencing, in-depth...
Pigs and chickens are the most common food animals that important vectors for spreading antimicrobial-resistant pathogens among humans. Limited systematic AMR monitoring of these animal origin bacteria had been reported, especially in developed areas China.
Antimicrobial resistance (AMR) has become a significant global challenge, with an estimated 10 million deaths annually by 2050. The emergence of AMR is mainly attributed to mobile genetic elements (MGEs or mobilomes), which accelerate wide dissemination among pathogens. interaction between mobilomes and genes (or resistomes) in Salmonella, primary cause diarrheal diseases that results over 90 cases annually, remains poorly understood. available fragmented incomplete genomes remain limitation...
(
Three Merino ewes, adapted for about 3 weeks to their environment, were bled at 10 min intervals through a jugular venous cannula. Radioimmunoassay of plasma samples cortisol revealed marked diurnal variations with peak levels just after midnight and lowest values in the afternoon. This rhythm appeared result from changing amplitude associated distinct ultradian (frequency 0·8–1·2 cycles/h) level cortisol. Calculation daily rate secretion hormone profiles gave mean value 8·49 mg. Arguments...
Cutaneous melanoma is very aggressive and results in high mortality rates for cancer patients. Determining molecular targets important developing novel therapies cutaneous melanoma. Cell division cycle associated 8 (CDCA8) a putative oncogene that upregulated multiple types of cancer. The present study aimed to examine the role CDCA8 melanoma, with focus on association its expression prognosis metastasis. First, mRNA tissues was investigated using ONCOMINE Gene Expression Omnibus (GEO)...
Amycolatopsis orientalis is the type species of genus and its industrial strain HCCB10007, derived from ATCC 43491, has been used for large-scale production vital antibiotic vancomycin. However, to date, neither complete genomic sequence this nor a systemic characterization vancomycin biosynthesis cluster (vcm) reported. With only whole genome mediterranei available, additional genomes other may facilitate intra-generic comparative analysis genus. The A. HCCB10007 comprises an 8,948,591-bp...
The wide spread of plasmid-borne mobilized colistin resistance (mcr) genes from animals to humans broadly challenges the clinical use polymyxins. Here, we evaluated incidence a recently reported mcr variant, mcr-10, in and same area. Our results revealed presence novel mcr-10-carrying plasmids two Klebsiella pneumoniae isolates chickens, one Escherichia coli isolate slaughterhouse workers, chromosome-borne mcr-10 gene Enterobacter kobei healthy resident region. It is worth mentioning that...
The worrying emergence of multiple resistance genes to last-resort antibiotics in food animals and human populations throughout the chain relevant environments has been increasingly reported worldwide. Enterobacteriaceae pathogens are considered most common reservoirs such antibiotic (ARGs). Thus, a rapid, efficient accurate detection method simultaneously screen monitor ARGs become an urgent need. Our study developed recombinase polymerase amplification (RPA) assay combined with lateral...
Strains of extraintestinal pathogenic Escherichia coli (ExPEC) can invade and colonize sites cause a wide range infections. Genomic analysis ExPEC has mainly focused on isolates human avian origins, with porcine yet to be sequenced. To better understand the genomic attributes underlying pathogenicity ExPEC, we isolated two E. strains PCN033 PCN061 from pigs, assessed their in vivo virulence, completed compared genomes. Animal experiments demonstrated that strain PCN033, but not PCN061, was...