- Advanced battery technologies research
- Supercapacitor Materials and Fabrication
- Intracerebral and Subarachnoid Hemorrhage Research
- Viral gastroenteritis research and epidemiology
- Advancements in Battery Materials
- Acute Ischemic Stroke Management
- Animal Virus Infections Studies
- Dementia and Cognitive Impairment Research
- Animal Disease Management and Epidemiology
- Plant Virus Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Covalent Organic Framework Applications
- Gut microbiota and health
- Hydrogen's biological and therapeutic effects
- Virus-based gene therapy research
- Electrochemical sensors and biosensors
- Electrocatalysts for Energy Conversion
- Vector-Borne Animal Diseases
- Advanced Battery Materials and Technologies
- Virology and Viral Diseases
- Cerebrospinal fluid and hydrocephalus
- Viral Infections and Immunology Research
- Advanced biosensing and bioanalysis techniques
- Industrial Vision Systems and Defect Detection
- Electrospun Nanofibers in Biomedical Applications
Kunming University of Science and Technology
2022-2025
Weifang Medical University
2024
Northeast Forestry University
2023-2024
Shanghai University of Medicine and Health Sciences
2024
Yangzhou University
2022-2024
Ministry of Agriculture and Rural Affairs
2022-2024
Jilin University
2023-2024
Fujian Medical University
2024
University of Illinois Urbana-Champaign
2024
China University of Mining and Technology
2023
Ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury, which serious clinical condition with no effective pharmacological treatment. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) significantly alleviate IRI; however, the underlying mechanisms and key molecules conferring renoprotection remain elusive. In this study, we characterized protein composition MSC-EVs using proteomics approach found that mitochondrial superoxide dismutase 2 (SOD2) was enriched in...
Chronic kidney disease (CKD) is characterized by persistent damage to function or structure. Progression end-stage leads adverse effects on multiple systems. However, owing its complex etiology and long-term cause, the molecular basis of CKD not completely known. To dissect potential important molecules during progression, based databases from Gene Expression Omnibus, we used weighted gene co-expression network analysis (WGCNA) identify key genes in tissues peripheral blood mononuclear cells...
Abstract Background Astroviruses (AstVs) are single-stranded RNA viruses that have been detected in a wide range of mammals and birds. They associated with numerous interspecies transmissions viral recombination events, posing threat to human animal health. Methods We collected 1,333 samples from wild animals, including bats, rodents, boars, birds, various states cities the Yunnan Province, China, between 2020 2023 investigate presence AstVs. AstVs were using polymerase chain reaction...
Rotavirus A (RVA) is the primary enteric pathogen of humans and many other species. However, RVA interspecies transmission remains poorly understood. In this study, we conducted a comprehensive screening genotyping analysis in 1706 wild animal samples collected from various regions within Yunnan Province, China. total 24 samples, originating boars, rodents, bats, birds tested positive for RVA. Next generation sequencing phylogenetic analyses revealed high degree genetic diversity...
Abstract Electrically conductive carbide ceramics with high hardness and fracture toughness are promising for advanced applications. However, enhancing both electrical conductivity simultaneous is challenging. This study reports the synthesis of (Ti 0.2 W Ta Hf Mo )C-diamond composites varying densities using high-pressure high-temperature (HPHT) method. The carbides uniformly dispersed in a titanium matrix, forming channels that reduce resistivity to 4.6×10 -7 Ω·m. These composite materials...
Background and Purpose: Cerebral small vessel disease (cSVD)—including white matter hyperintensities (WMHs), cerebral microbleeds (CMBs), lacunes, enlarged perivascular spaces (EPVS)—is related to gait impairment. However, the association between total magnetic resonance imaging (MRI) cSVD burden upper extremity function remains insufficiently investigated. This study aimed assess correlation MRI score impairment as well Method: A of 224 participants underwent scans, presence WMHs, CMBs,...
ABSTRACT Pseudorabies virus (PRV) is the causative agent of Aujeszky’s disease, which responsible for enormous economic losses to global pig industry. Although vaccination has been used prevent PRV infection, effectiveness vaccines greatly diminished with emergence variants. Therefore, there an urgent need develop anti-PRV drugs. Polyethylenimine (PEI) a cationic polymer and wide range antibacterial antiviral activities. This study found that low dose 1 µg/mL 25-kDa linear PEI had...
Introduction The Asian elephant ( Elephas maximus ) is a giant herbivore classified as an endangered wildlife species by the International Union for Conservation of Threatened Species.This study aims to investigate and compare core gut microbiota captive elephants from three different locations in Yunnan Province, China, explore impact environmental husbandry factors on microbial diversity. Methods We collected fecal samples 29 performed full-length 16S rRNA gene sequencing. Microbial...
A novel method termed cell surface engineering coupling biomembrane fusion based on metal organic layers was developed for dynamic membrane proteome profiling.
White matter hyperintensites (WMHs) , lacunes and brain atrophy have been demonstrated to be positively related gait disorder. However, cerebral microbleeds (CMBs) as a manifestation of small vessel disease (CSVD) is still under-investigated. Therefore, correlations between CMBs upper extremity, balance performance were investigated in this study.A cross-sectional study middle-aged older adults was conducted. CSVD burden measured with magnetic resonance imaging (MRI) the location number...
The pathogenesis of cerebral microbleeds (CMBs) is incompletely understood, but blood-brain barrier (BBB) leakage may play a key role. This study aimed to investigate the relationship between compromised BBB integrity and CMBs as well cognitive function.
Astroviruses (AstVs) are single-stranded RNA viruses, including two main genera: Mamastroviruses (MAstVs) and Avastroviruses (AAstVs). AstVs have been detected in more than 80 different mammals birds, with the characteristics of multiple cross-species transmission gene recombination. All these accelerated process virus mutation posed a potential threat to human beings animal husbandry. Yunnan province is global hotspot rich biodiversity abundant resources an important area significance for...