A5078565981- Cardiac, Anesthesia and Surgical Outcomes
- Total Knee Arthroplasty Outcomes
- Hip and Femur Fractures
- Health Systems, Economic Evaluations, Quality of Life
- Shoulder and Clavicle Injuries
- Central Venous Catheters and Hemodialysis
- Shoulder Injury and Treatment
- Cardiac and Coronary Surgery Techniques
- Orthopaedic implants and arthroplasty
- Enhanced Recovery After Surgery
- Trauma and Emergency Care Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Economic and Financial Impacts of Cancer
- Hip disorders and treatments
- Infection Control in Healthcare
- Meta-analysis and systematic reviews
- Prostate Cancer Treatment and Research
- HIV-related health complications and treatments
- Acute Lymphoblastic Leukemia research
- Aortic aneurysm repair treatments
- Antimicrobial Resistance in Staphylococcus
- Primary Care and Health Outcomes
- Musculoskeletal Disorders and Rehabilitation
- Urologic and reproductive health conditions
- Gastrointestinal disorders and treatments
University of Oxford
2015-2024
Trinity Laban Conservatoire of Music and Dance
2018-2020
New York University Press
2018-2020
Cambridge University Press
2018-2020
Advisory Board Company (United States)
2018-2020
Queen Mary University of London
2019-2020
Rex Hospital
2019-2020
Independent Dance
2019-2020
Ohio University
2020
University of Roehampton
2020
Uncertainty exists regarding the best management of patients with degenerative tears rotator cuff.To evaluate clinical effectiveness and cost-effectiveness arthroscopic open cuff repair in aged ≥ 50 years tendon tears.Two parallel-group randomised controlled trial.Nineteen teaching district general hospitals UK.Patients (n = 273) tears.Arthroscopic surgery repair, surgeons using their usual preferred method or repair. Follow-up was by telephone questionnaire at 2 8 weeks after postal 8, 12...
Contemporary trauma resuscitation prioritizes control of bleeding and uses major haemorrhage protocols (MHPs) to prevent treat coagulopathy. We aimed determine whether augmenting MHPs with Viscoelastic Haemostatic Assays (VHA) would improve outcomes compared Conventional Coagulation Tests (CCTs).This was a multi-centre, randomized controlled trial comparing in patients who received empiric MHPs, augmented by either VHA or CCT-guided interventions. Primary outcome the proportion subjects who,...
The appropriate management for patients with a degenerative tear of the rotator cuff remains controversial, but operative treatment, particularly arthroscopic surgery, is increasingly being used. Our aim in this paper was to compare effectiveness open repair cuff.A total 273 were recruited randomised comparison trial (136 surgery and 137 surgery) from 19 teaching general hospitals United Kingdom. surgeons used their usual preferred method repair. Oxford Shoulder Score (OSS), two years...
Objectives Through the National Health Service (NHS) Bowel Cancer Screening Programme (BCSP), men and women in England aged between 60 74 years are invited for colorectal cancer (CRC) screening every 2 using guaiac faecal occult blood test (gFOBT). The aim of this analysis was to estimate cost–utility immunochemical haemoglobin (FIT) compared with gFOBT a cohort beginning at range FIT positivity thresholds. Design We constructed cohort-based Markov state transition model CRC disease...
A trial-based comparison of the use resources, costs and quality life outcomes arthroscopic open surgical management for rotator cuff tears in United Kingdom NHS was performed using data from Rotator Cuff Study (UKUFF) randomised controlled trial.Using 273 patients, healthcare-related quality-adjusted years (QALYs) were estimated at 12 months 24 after surgery on an intention-to-treat basis with adjustment covariates. Uncertainty about incremental cost-effectiveness ratio versus follow-up...
Preventing CLABSI events in the dialysis inpatient population represents significant challenges. Bacteremia associated with lines or grafts are common health-associated infections that lead to adverse patient outcomes. Dialysis patients represent a much higher infection risk due health frequency needs, more frequent hospitalizations, multiple comorbidity issues, fistula functionality, and attempts for line access leading additional complications, costs, morbidity, mortality.An observational...
Background There is limited evidence concerning the effectiveness of enhanced recovery programmes in hip and knee replacement surgery, particularly when applied nationwide across a health-care system. Objectives To determine effect hospital organisation, surgical factors after surgery pathway on patient outcomes NHS costs replacement. Design (1) Statistical analysis national linked data to explore geographical variations surgery. (2) A natural experimental study clinical (3) qualitative...
Coronary artery bypass grafting (CABG) using bilateral internal mammary arteries (BIMA) may improve survival over CABG single (SIMA), but be surgically more complex (and therefore costly) and associated with impaired sternal wound healing. We report, for the first time, a detailed comparison of healthcare resource use costs 12 months, as part Arterial Revascularisation (ART) Trial. 3102 patients in 28 hospitals seven countries were randomised to surgery BIMA (n=1548) or SIMA (n=1554)....
To estimate the costs of primary hip and knee replacement in individuals with osteoarthritis up to 2 years postsurgery, compare before after surgery, identify predictors hospital costs.Patients age ≥18 planned or replacements England between 2008 2016 were identified from National Joint Registry linked Hospital Episode Statistics data containing inpatient episodes. Primary care outpatient records also used patients 2016. All health resource use was valued using 2016/2017 costs, nonparametric...
Aims It has been recommended that the percentage of high‐grade (HG) Gleason patterns 4 and 5 should be quantified in prostate cancer. However, this not assessed a cohort using cancer death as an outcome, there is debate to whether biopsy with ‘worst’ HG disease or ‘overall’ reported. Such data may assist active surveillance decisions. Methods results Men clinically localised diagnosed by needle from 1990 2003 were included. The endpoint was death. Clinical variables included score (GS),...
Objectives Effects of the UK Department Health’s national Enhanced Recovery After Surgery (ERAS) Programme on outcomes after primary hip replacement. Design Natural experimental study using interrupted time series to assess changes in trends before, during and ERAS implementation (April 2009 March 2011). Setting Surgeries National Joint Registry were linked with Hospital Episode Statistics containing inpatient episodes from Health Service trusts England patient reported outcome measures....
Abstract Aims Using bilateral internal thoracic arteries (BITAs) for coronary artery bypass grafting (CABG) has been suggested to improve survival compared CABG using single (SITAs) patients with advanced disease. We used data from the Arterial Revascularization Trial (ART) assess long-term cost-effectiveness of BITA SITA an English health system perspective. Methods and results Resource use, healthcare costs, quality-adjusted life years (QALYs) were assessed across 10 follow-up...
Background The use of bilateral internal thoracic arteries (BITA) for coronary artery bypass grafting (CABG) may improve survival compared with CABG using single (SITA). We assessed the long-term costs BITA SITA. Methods Between June 2004 and December 2007, 3102 patients from 28 hospitals in seven countries were randomised to surgery (n=1548) or SITA (n=1554). Detailed resource data collected initial hospital episode annually up 5 years. associated this a UK perspective year totals...
Highlights Using alcohol with CHG before accessing central line hubs helps reduce CLABSI events. vascular grafts A statistically significant reduction (65%) in events occurred after use. Statistically lower rates are sustainable use of CHG.