A5101607844- Pain Mechanisms and Treatments
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Peripheral Nerve Disorders
- Diabetic Foot Ulcer Assessment and Management
- Alzheimer's disease research and treatments
- Botulinum Toxin and Related Neurological Disorders
- Neurological and metabolic disorders
- Peripheral Neuropathies and Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Eosinophilic Disorders and Syndromes
- Neurological Disease Mechanisms and Treatments
- Immunotherapy and Immune Responses
- Occupational Health and Safety Management
- Skin Diseases and Diabetes
- Methodologies in Health Research and Practice
- Cardiovascular Health and Disease Prevention
- Biosensors and Analytical Detection
- Economic and Financial Impacts of Cancer
- Long-Term Effects of COVID-19
- Neurology and Historical Studies
- Sleep and Work-Related Fatigue
- Immune cells in cancer
- Hereditary Neurological Disorders
Sparrow Hospital
2019-2024
Airlangga University
2018-2022
Hebrew University of Jerusalem
2020
Regional Cancer Center
2011
Bristol-Myers Squibb (United States)
2007
Memorial Sloan Kettering Cancer Center
2007
Michigan State University
2005
The University of Texas Southwestern Medical Center
2000
Background and objective:Previous studies have shown that long-term outcomes are more favorable for patients newly diagnosed with chronic myeloid leukemia (CML) if a complete cytogenetic response is achieved within ≤12 months of diagnosis. Because continuous adequate dosing important to achieve this outcome, it understand treatment adherence as part managing CML therapy. While regarding imatinib suggest varies widely, data addressing newer breakpoint cluster region–Abelson (BCR-ABL)...
<p><strong>Objective. </strong>This paper describes our experience and outcomes from 54 cases presented to the (Molecular tumor board) MTB.</p><p><strong>Methods. </strong>54 Cases between July 2017 April 2018 were included in this analysis. These patients had different types of cancers that either failed standard therapy or expected fail physicians looking for future options anticipated progression. Patients who obvious mutations candidates Targeted...
7045 Background: Imatinib mesylate induces response in most patients with chronic myelogenous leukemia (CML). Although recent evidence shows benefit from a starting dose of 800mg/day, the recommended is 400 mg/day for phase and 600 accelerated phase/blast crisis patients. This study describes trends imatinib dosing reasons changes CML Methods: Using medical pharmacy claims HealthCore Managed Care Database, we identified all 1/1/00–3/31/04. Chart review supplemented confirmed diagnosis,...
To determine the inhibition effect of epigallocatechin gallate (EGCG) and green tea extract on neuronal necroptosis based morphology.In vivo study was performed male Rattus norvegicus middle cerebral artery occlusion (MCAO) model divided into five groups, MCAO-control EGCG 10 mg/kg BW/day, 20 30 BW/day for 7 days treatment. MCAO made by modification method using Bulldog clamp. After treatment, all R. were sacrificed. that, examination Hematoxylin-Eosin stain conducted to look at morphology...
BackgroundThe population of elderly people in Indonesia is increasing, so decrease cognitive function will be more common to found therefore the implementation activity reading as a nonpharmacologically management needed maximize elderly. Objectives:To know existence relation between frequency and duration Al-Quran with at elderly.Methods : This study used case-control sampling design that conducted according incident cases.In subjects performed examination MoCa-Ina questionnaire, then...
Patients treated with L-asparaginase may present hemorrhagic and thrombotic cerebrovascular events. This syndrome generally occurs after a few weeks of therapy occur is completed. Compli cations appear to result from depletion plasma proteins in volved coagulation fibrinolysis. Seizures are uncommon symptoms, always caused by We report case seizure associated but no evidence or cerebro vascular
Background: Distal diabetic sensorimotor polyneuropathy is a common complication occurred in diabetes mellituspatients.Even though the number of mellitus patients has been increasing, prevalence still far from its actual numbers due to diagnostic and method criteria.Objectives:We aimed determine Toronto Clinical Neuropathy (TCN) modified clinical neuropathy (mTCN) scores distal patients.Methods: Cross-sectional study was carried out October 29 th , 2014-June 1 st 2015 77 who visited...
Background and Objectives: Cytokines other immune regulatory molecules are critical for mounting an effective response against cancer. The gastrointestinal (GI) microbiome plays a significant role in the pathogenesis of cancer to immunotherapy. central hypothesis guiding this project was that specific biomarkers profiles will serve as predictors vs. ineffective immunotherapy patients with malignant diseases. This pilot feasibility study aims establish baseline markers subjects newly...
Introduction: Work fatigue is common in air and ground crew since they have prolonged working hours. excessive tiredness decreased function during or after work. Fatigue can also affect sleep quality. Despite work causing disproportionately significant psychosocial dangers, limited studies developed an intervention program. Thus, this study will develop a Intervention Program (FIP) evaluate its effectiveness reducing fatigue. Methods: The FIP was literature review expert’s evaluation. This...
Background: HIV infection leads to neurological damage that results in cognitive and behavioural impairment called HIV-associated neurocognitive disorder (HAND). There are several factors associated with HAND which include the CD4 count. Patients who present level lower than 200 cells/mm 3 considered very vulnerable of experiencing complications such as HAND. Objective: To investigate association between evaluated using MoCA-INA among patients. Materials Method: This cross-sectional study...
Background: The increased serum uric acid (SUA) levels have been linked to macro vascular disease in Type 2 Diabetes Melitus. correlation between and diabetic peripheral neuropathy has not addressed properly.
 Objective: aim of this study was determine the high neuropathy.
 Methods: This a case-control design sampling done consecutively by following inclusion exclusion criteria. evaluated using Electroneuromyography (EMNG) were taken for level examination. Chi square test used...
Guillain-Barre syndrome (GBS) is a common cause of inflammation-related acute flaccid paralysis, and characterized by onset, rapid progression, symmetrical weakness. GBS an emergency with high morbidity long-term disability rates. It important to determine the prognostic factors for in order improve disease outcomes. This study aimed identify correlation between neutrophil-to-lymphocyte ratio (NLR) on day 1 hospitalization (D1) motor deterioration patients.This observational analytical...
Background and Objective. The poor control of blood glucose levels in patients with diabetes mellitus is a major risk factor from various complications mellitus, such as polyneuropathy. One the nerves that are often affected case diabetic neuropathy peroneal nerve. This study aimed to determine association between level measured serum hemoglobin A1c (HBA1c) motor nerve conduction velocity type 2 Methods. was conducted on who fulfilled inclusion exclusion criteria neurology unit Dr. Soetomo...
Background: Diabetic Peripheral Neuropathy is a chronic microvascular complication of type 2 diabetes mellitus (T2DM) leads to increased risk foot ulceration and morbidity.The serum uric acid (SUA) levels have been linked macro vascular disease in T2DM. We found that the correlation between SUA diabetic peripheral neuropathy has not investigated. Objective: To determine high neuropathy. Method: The case-control design was used this study sampling done consecutively by following inclusion...
Background: High levels of fibrinogen will increase the blood viscosity. Pulsatility index parameter intranscranial doppler can measure vessel resistance which influence by cerebral flow velocityand This study has aim to find correlation between with PI in acute thromboticstroke patient.Method: A cross sectional design was used this study. The samples were patient ischemic strokein neurological ward Dr. Soetomo Hospital Surabaya from January 2019 December 2020. Fibrinogenlevel measured using...
Abstract Cytokines and other immune regulatory molecules are critical players in the response against cancer. There is growing interest testing potential utility of systemic biomarkers to track cancer progression use them as predictors effective responses therapy. The central hypothesis guiding this project that specific will serve vs. ineffective immunotherapy patients with malignant diseases. objective study was establish baseline markers already started treatment (n=10) (T), starting, but...