Chizuo Iwai
A5023481166- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Management of metastatic bone disease
- Pelvic and Acetabular Injuries
- Spinal Dysraphism and Malformations
- Scoliosis diagnosis and treatment
- Infectious Diseases and Tuberculosis
- Nerve Injury and Rehabilitation
- Spinal Cord Injury Research
- Spinal Hematomas and Complications
- Neurofibromatosis and Schwannoma Cases
- Bone Tumor Diagnosis and Treatments
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Medical Imaging and Analysis
- Pneumothorax, Barotrauma, Emphysema
- Neuroblastoma Research and Treatments
- Anorectal Disease Treatments and Outcomes
- Fetal and Pediatric Neurological Disorders
- Surgical site infection prevention
- Cerebrospinal fluid and hydrocephalus
- Musculoskeletal pain and rehabilitation
- Hip disorders and treatments
- Dysphagia Assessment and Management
Gifu University Hospital
2024-2025
Gifu University
2010-2025
Institute for Conflict Research
2024
Weatherford College
2022
Gifu Prefectural General Medical Center
2021
Dokkyo Medical University
2012
Abstract Attenuation of the secondary injury spinal cord (SCI) can suppress spread tissue damage, possibly resulting in sparing that improve functional prognoses. Granulocyte colony-stimulating factor (G-CSF) is a haematological cytokine commonly used to treat neutropenia. Previous reports have shown G-CSF promotes recovery rodent models SCI. Based on preclinical results, we conducted early phase clinical trials, showing safety/feasibility and suggestive efficacy. These lines evidence...
A prospective study on the clinical outcomes in patients with tuberculous spondylitis treated by a 2-stage operation (posterior and anterior) using posterior spinal instrumentation.To evaluate of surgical treatment (first stage: placement instrumentation second anterior debridement bone grafting) for spondylitis.There have been few reports describing effects spondylitis.Ten (5 men 5 women) were operations. Age at initial was 64.6+/-14.8 years (average+/-SD) (range: 47 to 83 y). The evaluated...
Study Design. Retrospective analysis of data collected across multiple centers. Objective. To develop machine learning models for predicting neurological outcomes one month postoperatively in patients with metastatic spinal tumors undergoing surgery, and to identify key factors influencing recovery. Summary Background Data. The increasing prevalence metastases has led a growing need surgical intervention address mechanical instability deficits. Predicting postoperative status, as assessed by...
Study Design. Prospective multicenter study. Objective. To investigate risk factors for 3-month postoperative mortality in metastatic spinal tumor surgery, focusing on nutritional biomarkers and prognostic scores alongside clinical indicators. Summary of Background Data. Metastatic tumors affect patient morbidity mortality. Although tools exist, they have limitations, particularly emergency situations requiring rapid assessment. Nutritional may influence outcomes, but their role predicting...
This study aimed to determine the index of sacral vertebrae fusion period in children and adolescents diagnose lesion around spine accurately. Patients aged 0-40 years who underwent computed tomography (CT), including normal sacrum for screening abdominal disorders pan-scan trauma between 2019 2022 were retrospectively examined. There 402 eligible sacra (385 patients: 206 women 179 men). We evaluated bony at six parts (anterior or posterior each intervertebral both side lateral masses). The...
Granulocyte colony-stimulating factor (G-CSF) is generally used for neutropaenia. Previous experimental studies revealed that G-CSF promoted neurological recovery after spinal cord injury (SCI). Next, we moved to early phase of clinical trials. In a I/IIa trial, no adverse events were observed. conducted non-randomised, non-blinded, comparative which suggested the efficacy promoting recovery. Based on those results, are now performing III trial.The objective this study evaluate acute SCI....
Retrospective study.To analyze the clinical outcomes of anterior and posterior spinal fusion (APSF) using a fibular strut autograft (FSAG) to investigate morphological changes in reconstructed column dystrophic deformities neurofibromatosis (NF)-1.APSF is desirable for NF-1 with more than 50° kyphosis. There are few reports regarding APSF which over time graft have been investigated.The radiographic FSAG were investigated 10 consecutive patients deformity NF-1. For qualitative quantitative...
Aims Dilated cardiomyopathy is partly caused by a mutation of some cytoskeletal or nuclear envelope proteins. It has been confirmed recently that missense the gene encoding desmin, protein, can cause dilated cardiomyopathy. This study was aimed at elucidating frequency and clinical characteristics desmin mutation.
Clinical and basic study.
Study Design Prospective multicenter study. Objectives Palliative surgery is crucial for maintaining the quality of life (QOL) in patients with spinal metastases. This study aimed to compare short-term outcomes QOL after palliative between metastatic tumors at different segments. Methods We prospectively compared data 203 metastases 2-3 consecutive segments who were divided into following three groups: cervical, cervical spine lesions; thoracic, upper–middle thoracic and TL/L/S, lesions...
Abstract Background Meningioma is the second most common intradural extramedullary tumor, following schwannoma. primarily categorized as benign World Health Organization grade 1, but clear cell meningioma 2 of intermediate malignant category. Clear meningiomas are rare, accounting for less than 1% all tumors. There no previous report multiple intraspinal without dural attachment. Case presentation A 27-year-old Asian male patient presented with lower right extremity pain, and had undergone...
Case: A 30-year-old man had cervical radiculomyelopathy and neck pain caused by a massive intraosseous neurofibroma (IONF) originating from the C6 vertebrae. We performed posterior tumor resection with spinal instrumentation fusion C3 to T2 follow-up procedure of remaining anterior tumor, sacrificing affected vertebral artery (VA), which accordingly required bypass surgery at 2 months recovery. Reconstruction using titanium mesh cage was successfully performed. There were no local...
<title>Abstract</title> Background This study aimed to determine the index of sacral vertebrae fusion period in children and adolescents diagnose lesion around spine accurately. Methods Patients aged 0–40 years who underwent computed tomography (CT), including sacrum, for abdominal disorders, trauma, etc., between 2019 2022 were retrospectively examined. There 402 eligible sacra (385 patients: 206 women 179 men). We evaluated bony at six parts (anterior or posterior each intervertebral both...
Multicenter, prospective registry study.
Instrumentation surgery in combination with radiotherapy (RT) is one of the key management strategies for patients spinal metastases. However, use materials can affect RT dose delivered to tumor site and surrounding tissues, as well hinder optimal postoperative evaluation. The association preoperative Spine Instability Neoplastic Score (SINS) need stabilization life expectancy are unclear. This multicenter prospective study aimed investigate current situation make recommendations regarding...
Neurogenic acute respiratory failure is usually caused by either infection or vascular insufficiency. We report the case of a patient who developed secondary to spinal tumor.A 32-year-old man, presenting with numbness and muscle weakness in his legs for 2 weeks, was transferred our hospital worsening quadriplegia development symptoms. carried out emergent decompression initiated steroid pulse therapy, no resolution symptoms; tumor incision biopsy after contrast cervical magnetic resonance...
Spinal cord injury in elderly populations has increased recent years. This study aimed to investigate the pathology, severity, efficacy of surgery, and complications cervical spinal extremely patients aged >80 Sixty-three who underwent surgical treatment for were enrolled this retrospective multicenter study. Forty <80 years (Group 1), 23 ≥80 2). The etiology injury, American Injury Association impairment scale (AIS) grade, procedure, neurological improvement, evaluated. Most causes...
We report a rare case of rigid spinal deformity with severe pelvic obliquity (PO) resulting from hip ankylosis caused by childhood tuberculosis (TB). A 66-year-old woman presented left knee pain, chronic low back and fatigability during walking. She leg length discrepancy (LLD) due to an ankylosed right joint, PO, secondary lumbar scoliosis. Total arthroplasty (THA) adductor tendonectomy were performed prior spine surgery, posterior correction fusion T10 the pelvis. Prior we predicted that...