A5032824292- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Renal Transplantation Outcomes and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Nutrition and Health in Aging
- Tuberculosis Research and Epidemiology
- Diet and metabolism studies
- Transplantation: Methods and Outcomes
- Biliary and Gastrointestinal Fistulas
- Cardiovascular Function and Risk Factors
- Cardiac Ischemia and Reperfusion
- Bariatric Surgery and Outcomes
- Trauma Management and Diagnosis
- Mechanical Circulatory Support Devices
- Nanoparticle-Based Drug Delivery
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- Organ Donation and Transplantation
- Cardiac and Coronary Surgery Techniques
- Pleural and Pulmonary Diseases
- Pneumothorax, Barotrauma, Emphysema
Hospital Beatriz Ângelo
2024
Hospital das Clínicas da Universidade Federal de Minas Gerais
2008-2022
Pitié-Salpêtrière Hospital
2021
Universidade Federal de Minas Gerais
2009-2021
Assistance Publique – Hôpitaux de Paris
2021
Hôpitaux Universitaires Henri-Mondor
2021
Sorbonne Université
2021
Harvard University
2019
Roche (Portugal)
2011-2012
Cartilage tissue has poor capability of self-repair, especially in the case severe cartilage damage due to trauma or age-related degeneration. Cell-based engineering using scaffolds provided an option for repair defects adult tissue. Mesenchymal stem cells (MSC) and chondrocytes are two major cell sources engineering. The present study combined culture conditions MSC a chitosan-gelatin matrix chondrogenic media evaluate their effects on viability chondrogenesis were harvested from rabbit...
Tuberculosis (TB) is an important opportunistic infection in transplant recipients worldwide. The frequency of Mycobacterium tuberculosis disease varies among different regions, but the incidence TB adult liver (LT) largely unknown. estimated ranges from 0.7% to 2.3%, with mortality rate up 30%. However, these data are based on individual case reports or series small samples. In LT recipients, therapy generally associated significant hepatotoxicity and interactions immunosuppressive...
Pancreas transplantation involves a set of procedures that, in some cases, lead to different complications and outcomes. The aim this study was analyze the long-term effects pancreas regarding carbohydrate lipid metabolism parameters determine differences between simultaneous pancreas-kidney (SPK) alone (PTA).Sixty-four patients (46 SPK 18 PTA), with an immunosuppression protocol based on tacrolimus plus mycophenolate mofetil prednisone, were evaluated for at least 1 year after...
PURPOSE: To evaluate the effects of hyperbaric oxygen (HO) therapy in protection against liver ischemia/reperfusion injury. METHODS: Thirty-two male Wistar rats were divided into four groups eight animals each: group A - laparotomy and manipulation, B ischemia reperfusion, C HO pretreatment for 60 min followed by D with ambient air at 2.5 absolute atmospheres reperfusion. Plasma was assayed aspartate aminotransferase (AST), alanine (ALT) lactate dehydrogenase (LDH). Intra-arterial blood...
Patients with end stage liver disease (ESLD) referred for transplantation (LT) are forwarded to pulmonary evaluation before being operated. ESLD is associated muscle wasting, reduced exercise tolerance and aerobic capacity.We assessed the association between capacity (AC), severity postoperative LT outcomes in a series of candidates university affiliated hospital Brazil.Pre-LT oxygen uptake at peak (pre-VO2peak), severity, early pos-LT such as length intensive care unit (ICU) stay, <5 ≥5...
Primary graft dysfunction is a major cause of mortality after heart transplantation.To evaluate correlations between donor-related clinical/biochemical markers and the occurrence primary dysfunction/clinical outcomes recipients within 30 days transplant.The prospective study involved 43 donor/recipient pairs. Data collected from donors included demographic echocardiographic information, noradrenaline administration rates concentrations soluble tumor necrosis factor receptors (sTNFR1 sTNFR2),...
Liver transplant (LT) surgery is associated with significant bleeding in 20% of cases, and several authors have demonstrated the risks related to blood components. The objective present study was evaluate impact using components during hospitalization five-year survival patients undergoing LT.One hundred thirteen were evaluated retrospectively. Several variables, including use intraoperatively throughout hospitalization, categorized by univariate analysis Fisher's test. A level significance...
We have observed different clinical responses to botulinum toxin A (BTX-A) in patients who had similar urodynamic parameters before the procedure. Furthermore, some bladders evaluated by cystography and cystoscopy during procedure characteristics that could influence outcome of treatment. The aim this study was assess whether help predict which with neurogenic detrusor overactivity (NDO) refractory anticholinergics respond better treatment injection BTX-A. In total, 34 spinal cord injury...
OBJETIVO: Este estudo analisa de forma retrospectiva o perfil lipídico pacientes submetidos à derivação gástrica a Fobi-Capella, na Santa Casa Belo Horizonte setembro 1999 2003. MÉTODO: Foram avaliados os protocolos acompanhamento 143 pacientes, analisando valores colesterol total (CT), associado lipoproteína alta densidade (HDL), baixa (LDL), triglicérides (TG) e índice massa corporal (IMC) no pré-operatório um ano após operação. A presença dislipidemia foi definida como alteração em pelo...
To compare the lipid profile (total cholesterol - TC, triglycerides TG, high density lipoprotein HDL-c, low LDL-c and non-HDL NHDL-c) of patients with functioning pancreas-kidney transplantation (PKT) or pancreas alone (PTA) after one (T1) two yr (T2) following their pre-transplantation data (T0).Fifty-three type 1 diabetic underwent (42 PKT 11 PTA) remaining euglycemic were evaluated before procedures. They using predominantly tacrolimus-mycophenolate mofetil-based immunosuppression...
Donor-derived tuberculosis (DD-TB) accounts for less than 5% of TB cases and is considered a rare event. In the transplant setting, frequency active estimated to be 20 74 times higher that in general population, it associated with high mortality. this context, main strategy minimize risk DD transmission identify high-risk donors. Despite screening recommendations, failures may result breakdown safety ends potentially fatal diseases. This report describes case DD-TB emphasizes communication...
Cholangiocarcinoma (CCA) is the second most malignant neoplasm in liver that arises from biliary tree. CCA associated with a poor prognosis, and key players involved its pathogenesis are still not well understood. Receptor tyrosine kinases (RTKs), such as epidermal growth factor receptor (EGFR), can mediate intracellular calcium (Ca2+) signaling pathways via inositol 1,4,5-trisphosphate (InsP3), activating receptors (ITPRs) regulating tumor growth. ITPR isoform 3 (ITPR3) main Ca2+ release...
to investigate the effect of standardized interventions in management tube thoracostomy patients and assess independent each intervention.A chest protocol was assessed a retrospective cohort study. The (TTP) implemented August 2012, consisted of: antimicrobial prophylaxis, insertion operating room (OR), admission post (CTT) hospital floor separate from emergency department (ED), daily respiratory therapy (RT) sessions post-CTT. inclusion criteria were, hemodynamic stability, between ages 15...
Solid pseudopapillary neoplasm (SPPN) was first characterized by Virginia Frantz in 1959. The duodenum-preserving pancreatic head resection (DPPHR) has been described as treatment for low-grade malignant tumors of the pancreas including eight cases SPPN.A 16-year-old white female patient presented with abdominal pain and dyspepsia. Computed tomography scan abdomen showed a 10×9×10cm(3) lesion on head. After radiological diagnosis SPPN submitted to DPPHR. Resection achieved clear margins....
Surface functionalization of nanoparticles (NPs) may alter their biological interactions such as uptake by alveolar macrophages (AMs).Pulmonary delivery gold NPs (Au NPs) has theranostic potential due to optoelectronic properties, minimal alveoli blood translocation, and possibility specific cell targeting.Here, we examined whether coating Au with transferrin alters protein corona, macrophages, pulmonary translocation.Methods: Rats were intratracheally instilled transferrin-coated (Tf-Au or...