A5047818899- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Head and Neck Cancer Studies
- Graphene and Nanomaterials Applications
- Autism Spectrum Disorder Research
- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Anatomy and Medical Technology
- Cleft Lip and Palate Research
- Tumors and Oncological Cases
- Surgical Simulation and Training
- Dysphagia Assessment and Management
- Nanoparticles: synthesis and applications
- Vascular Tumors and Angiosarcomas
- Nasal Surgery and Airway Studies
- Protease and Inhibitor Mechanisms
- Tracheal and airway disorders
- Congenital Ear and Nasal Anomalies
- Autophagy in Disease and Therapy
- RNA modifications and cancer
- Salivary Gland Tumors Diagnosis and Treatment
- Liver physiology and pathology
- Otitis Media and Relapsing Polychondritis
- Facial Trauma and Fracture Management
- Sarcoma Diagnosis and Treatment
Medical University of Silesia
2016-2025
University of Silesia in Katowice
2024-2025
AGH University of Krakow
2015
Górnośląskie Centrum Medyczne
2013
Cephalic index is a highly useful method for planning surgical procedures, as well assessing their effectiveness in correcting cranial deformations children. There are relatively very few studies measuring cephalic healthy Caucasian young The aim of our study was to develop classification current children up 3 years age with normal brain development, using axial slice computer tomography performed thin slices (0.5 mm) resulting more accurate measurements. 180 infants (83 females and 97...
Recent advances in 3D printing technology, and biomaterials are revolutionizing medicine. The beneficiaries of this technology primarily patients, but also students medical faculties. Taking into account that not all have full, direct access to the latest additive technologies, we surveyed their opinion on education area. research aimed determine what knowledge about use medicine, do faculties have.The was carried out form a questionnaire among 430 Medical University Silesia Katowice...
Autism Spectrum Disorder (ASD) is the most recognized neuropsychiatric disorder of childhood. Comorbid conditions (such as feeding disorders) are more common among people with autism than general population. The frequent somatic disorders in autistic children include gastrointestinal observed 46-91% patients. purpose this study was evaluation nutrition autism, particular emphasis placed on first year life, comparison to group healthy peers. Participants included 75 Caucasian (41 diagnosed...
Abstract Adjuvant chemotherapy with 5-fluorouracil (5-FU) does not improve survival of patients suffering from a form colorectal cancer (CRC) characterized by high level microsatellite instability (MSI-H). Given the importance autophagy and multi-drug-resistant (MDR) proteins in resistance, as well role casein kinase 1-alpha (CK1α) regulation autophagy, we tested combined effect 5-FU CK1α inhibitor (D4476) on HCT116 cells model MSI-H cancer. To achieve this goal, gene expression Beclin1 MDR...
The Conscious Body Donation Program conducted since 2003 by the Department of Human Anatomy, Medical University Silesia in Katowice was first innovative project aimed at obtaining informed donors' bodies for purpose teaching anatomy Poland. aim this prospective study to determine declared characteristics and establish possible motivation body donation. A total 244 application files were reviewed following information analyzed: donor's age, age which decision donate made, place residence...
Anthropometric analysis of the midface is essential, especially for rhinoplasty surgeons, medical aesthetics, jurisprudence, and anthropology. The aim this study was to provide data describe anthropometric dimensions nose face among Caucasian young adults in order establish reference values. conducted 289 Polish students (115 men 174 women). mean age group 20.44 ± 1.93 years. In 10 linear measurements were determined, 7 indices calculated, including Facial Index Nasal Index. prevalence...
The anticancer potential of quercetin (Q), a plant-derived flavonoid, and underlining molecular mechanisms are widely documented in cellular models vitro. However, biomedical applications Q limited due to its low bioavailability hydrophilicity. In the present study, electrospinning approach was used obtain polylactide (PLA) PLA polyethylene oxide (PEO)-based micro- nanofibers containing Q, namely PLA/Q PLA/PEO/Q, respectively, form non-woven fabrics. structure physico-chemical properties...
Head and neck cancer (HNC) shows a "diverging scissors" pattern, with incidence mortality linked to regional economic status. We aim investigate whether socioeconomic disparities between regions correlate widening gaps in HNC rates, particular emphasis on age-related patterns among elderly populations. Cross-sectional study. Data from the National Cancer Registry for females 2003 2019. 76 649 patients, 49 858 males, 26 791 2019 age cohorts: 60-69, 70-79, 80+, covering all voivodeships...
To analyze potential associations between three polymorphisms (rs3818188, rs941793, rs2403015) of the DYNC1H1 gene and occurrence autism spectrum disorder as well clinical phenotype affected individuals. This family-based study included 206 children diagnosed with ASD 364 their biological parents. examine association occurrence, a transmission disequilibrium test was performed. Additionally, studied individuals were analyzed using χ2 test. None showed an in overall patient group. However,...
Drug-resistant epilepsies still remain one of the most profound problems contemporary epileptology. Several mechanisms drug resistance are possible; among them, genetic factors have a prominent place. Much importance is attached to genes, which encode enzymes that metabolize antiepileptic drugs CYP 3A, belong family cytochromes P450 and genome multidrug resistance, such as 1 (MDR1) expresses P-glycoprotein (P-gp), transporter protein. The aim study was assess relation between polymorphism...
Human body is the most perfect atlas of human anatomy. Body donation after death is, next to organs for purpose transplantation, another altruistic act, which significantly influences future medicine, as regards teaching anatomy and clinical disciplines. Because students are mainly beneficiaries corpse donations, it appears important learn about their attitudes this act. The was assess awareness nursing physiotherapy towards educational scientific purposes.A total 128 Polish (110 women 18...
Silver nanoparticles (NPs) have at least one dimension of a particle smaller than 100 nm and contain 20-15,000 silver atoms. Due to its antibacterial activity nanosilver (NS) is used for medical purposes. NS particles can be obtained by various methods. Potentially, the best method synthesis purposes based on brief flow electric current between two electrodes placed in deionized water. It accepted that major effect partial oxidation releasing ions, which interact with thiol groups...
Atresias of nasal cavity, especially in young children, pose an essential problem children’s otolaryngology. Only a few morphometric studies cavity concerning healthy neonates and infants without stenosis are available. Multislice computed tomography is perfect tool enabling precise evaluation anatomic structures. The aim this study was complex clinically important bone mucosal structures examination their dependence on age sex children up to 3 years age. 180 range 0–3 years, were divided...
Polycaprolactone (PCL) is a biodegradable polyester that might be used in tissue engineering to obtain scaffolds for bone reconstruction using 3D-printing technologies. New material compositions based on PCL, with improved physicochemical properties and excellent biocompatibility, would improve its applicability regeneration. The aim of this study was assess the potential toxic effects PCL-based composite materials containing 5% hydroxyapatite (PCL/SHAP), bioglass (PCL/BIO), or chitosan...
With the rapid advancement of regenerative medicine technologies, there is an urgent need for development new, cell-friendly techniques obtaining nanofibers-the raw material artificial extracellular matrix production. We investigated structure and properties PCL10 nanofibers, PCL5/PCL10 core-shell type as well PCL5/PCLAg nanofibres prepared by electrospinning. For production fiber variants, a 5-10% solution polycaprolactone (PCL) (Mw = 70,000-90,000), dissolved in mixture formic acid acetic...
Micro-RNAs (miRs) represent an innovative class of genes that act as regulators gene expression. Recently, the aberrant expression several miRs has been associated with different types cancers. In this study, we show miR301 inhibition influences PI3K-Akt pathway activity. Akt overexpression in MCF7 and MDAMB468 cells caused downregulation This effect was confirmed by co-transfection miR301-modulators presence Akt. Cells overexpressing miR301-inhibitor Akt, exhibited increased migration...