A5001196512- Cancer, Lipids, and Metabolism
- Gastric Cancer Management and Outcomes
- Traditional Chinese Medicine Analysis
- Helicobacter pylori-related gastroenterology studies
- Plant-based Medicinal Research
- Pharmacological Effects of Natural Compounds
- Botanical Studies and Applications
- Child Nutrition and Feeding Issues
- Cancer Cells and Metastasis
- Reproductive Health and Contraception
- Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Otolaryngology and Infectious Diseases
- Multiple and Secondary Primary Cancers
- Diverticular Disease and Complications
- Sinusitis and nasal conditions
- Drug-Induced Hepatotoxicity and Protection
- Anorectal Disease Treatments and Outcomes
- Ovarian function and disorders
- Trauma Management and Diagnosis
- Head and Neck Anomalies
- Dysphagia Assessment and Management
- Bone Metabolism and Diseases
- Pharmacological Effects of Medicinal Plants
- Fungal Biology and Applications
Chiayi Chang Gung Memorial Hospital
2020-2025
Chang Gung University
2021-2024
Chang Gung Memorial Hospital
2012-2023
National Taiwan University
2015
Memorial Hospital of South Bend
2015
Rutgers Cancer Institute of New Jersey
2011
Rutgers, The State University of New Jersey
2011
Robert Wood Johnson University Hospital
2009
University of Connecticut
2009
Background. Traditional Chinese medicine (TCM) includes herbal products (CHPs), acupuncture, and traumatology manipulative therapies. TCM physicians often prescribe CHP to treat patients with osteoporosis; however, the drugs used their patterns of prescriptions have yet be characterized. This study, therefore, aimed evaluate for treatment osteoporosis in Taiwan prescription patterns. Methods. A cohort one million randomly sampled cases from National Health Insurance Research Database (NHIRD)...
Prostate cancer remains a significant global health challenge, necessitating the development of novel therapeutic approaches. This study investigated potential Antrodia cinnamomea formula (XIANZHIFANG formula, XZF), comprising cinnamomea, Sanghuangporus sanghuang, Ganoderma lucidum, sinense, and Inonotus obliquus, in prostate treatment. HPLC analysis confirmed presence key triterpenoids, including Antcin A, B, C, K, Zhankuic acid 4,7-dimethoxy-5-methyl-1,3-benzodioxole. Cytotoxicity assays...
Chinese herbal products (CHPs) have been frequently used among patients with chronic diseases including hypertension; however, the co-prescription pattern of formulae and single herbs remain uncharacterized. Thus, this large-scale pharmacoepidemiological study evaluated frequency CHPs for treating hypertension in Taiwan from 2003 to 2009.The database traditional medicine (TCM) outpatient claims was obtained National Health Insurance Taiwan. Patients during period were defined according...
Background: Numerous studies have revealed that statins antitumor effects in vivo and vitro. However, few explored the relationship between statin use mortality of gastric cancer (GC) patients after treatments. This study examines overall survival (OS) GC surgery adjuvant chemotherapy, using data from nationwide cohort database Taiwan. Methods: All newly diagnosed with 1999 to 2008 Taiwan were identified Registry Catastrophic Illness Patients Database. Through propensity score matching,...
Background. Gastric cancer remains a major globally. More than half of patients with gastric undergo surgery in Taiwan; however, few large nationwide studies have investigated the effects traditional Chinese medicine (TCM) on management after surgery. This study aimed to evaluate effect TCM following and adjuvant chemotherapy Taiwan its prescription trends. Methods Materials. The cohort sampling data set was obtained from Registry Catastrophic Illness Patient Database, research database...
Background: Mastitis is a common disorder among postpartum women. The discomfort and pain caused by mastitis may lead to the discontinuation of breastfeeding. Large-scale epidemiological studies examining are limited. Accordingly, present study used nationwide population-based database collect information about all women in Taiwan determine incidence related factors for mastitis. Materials Methods: This retrospective National Health Insurance Research Database records patients with during...
At the time of writing, more than 440 million confirmed coronavirus disease 2019 (COVID-19) cases and 5.97 COVID-19 deaths worldwide have been reported by World Health Organization since start outbreak pandemic in Wuhan, China. During pandemic, many variants SARS-CoV-2 arisen because high mutation rates. N501Y, E484K, K417N, K417T, L452R T478K receptor binding domain (RBD) region may increase infectivity several SARS-CoV-2. In this study, we discovered that GB-1, developed from Chiehyuan...
Peritonsillar abscess (PTA) is an infectious emergency in the head and neck, patients with end-stage renal disease (ESRD) have immunocompromised status. However, no relevant research has focused on ESRD-PTA relationship. This study explored PTA ESRD their prognosis.We identified 157,026 diagnosed as having over January 1997 to December 2013 from Taiwan's National Health Insurance Research Database (NHIRD). Each patient (hereafter, patients) was matched one control without chronic kidney...
Intussusception is frequently observed pediatric emergency that often followed by recurrent intussusception after initial treatment. This study investigated the risk factors associated with in children aged ≤ 3 years. Between January 2007 and December 2015, a cohort was conducted linking Taiwan Maternal Child Health Database to Birth Certificate Application database National Insurance Research Taiwan. Patients years diagnosis related treatment were included our study. Multivariable logistic...
The Chiehyuan herbal oral protection solution (GB-2) is a mixture commonly utilized in Taiwan for combating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as per traditional Chinese medicine practices. This study assessed the clinical impact of GB-2 through prospective trials. With twice-daily use week, was shown to diminish expression angiotensin-converting enzyme (ACE2) mucosal cells. Moreover, after two weeks use, it could reduce transmembrane protease, serine (TMRPSS2)...
Background: Hemorrhoids, a gastrointestinal tract disorder, are common during pregnancy. However, large-scale epidemiological studies on hemorrhoids pregnancy limited. Therefore, this study used analyzed data from nationwide population-based database to investigate the prevalence, characteristics, and treatment of in Taiwan. Materials Methods: This retrospective National Health Insurance Research Database Taiwan Birth Certificate Application collect medical records women who were pregnant at...
Abstract Objective The association between gastroesophageal reflux disease (GERD) and laryngeal disorders remains debatable, although it has been the focus of extensive clinical laboratory research. We conducted this study to obtain evidence on association. Study Design Population‐based cohort study. Setting Taiwan National Health Insurance Research Database (NHIRD). Methods Using data from Taiwan's NHIRD (January 2000 December 2018), we performed a population‐based analysis estimate risk in...
<title>Abstract</title> Background Traditional Chinese medicine (TCM) is widely applied in assisted reproductive technology (ART). However, TCM drug utilization and prescription patterns reproduction remain unclear. This study was conducted to analyze these patterns. Methods Using data from Taiwan’s Artificial Reproductive Database National Health Insurance Research Database, we analyzed the frequency of prescriptions proportions which different herbal formulae individual herbs were...
Chronic rhinosinusitis (CRS) affects the quality of life many people worldwide and can cause comorbidities. Our previous research proved that Sjogren's syndrome (SS) is a predisposing factor for CRS, with 2.5-fold associated risk. Antibiotics are important in CRS treatment; however, there paucity on pathogenic bacteria SS-CRS past. We conducted this study to investigate difference non-SS-CRS aimed give clinicians references when selecting antibiotics treat SS-CRS.A total 14,678 patients...
To determine whether exposure to antidepressants (ATDs) results in improved overall survival (OS) of patients with gastric cancer (GC) after surgery, we conducted a large cohort study and considered confounding factors that might affect the research outcomes.Patients who received new diagnosis GC surgery chemotherapy between 1999 2008 were recruited classified into different groups based on ATD level used. The association OS levels use, hazard ratio comorbidities at use compared.According...
64 Background: Radiation therapy (RAD) is commonly employed to treat localized prostate cancer; however, representative data regarding treatment related toxicities compared conservative management (CM) sparse. Methods: We performed a population-based cohort study, using Medicare claims linked the Surveillance, Epidemiology, and End Results data, evaluate gastrointestinal (GI) in men aged 65-85 years treated with either primary RAD or CM for T1-T2 cancer diagnosed 1992-2005. In this only GI...
5010 Background: The natural history of screen-detected prostate cancer has not been well described. Methods: Cancer-specific and overall mortality, assessed through competing risk analyses, were determined for 14,516 men aged 65 years or older diagnosed between 1992–2002 did receive surgery radiation within 6 months diagnosis. population-based cohort was identified from US registries, which had 98% completeness in case ascertainment. Results: Compared to earlier era studies, survival...