A5012426500- Fault Detection and Control Systems
- interferon and immune responses
- Advanced Control Systems Optimization
- Sepsis Diagnosis and Treatment
- Control Systems and Identification
- Artificial Immune Systems Applications
- Transplantation: Methods and Outcomes
- Endoplasmic Reticulum Stress and Disease
- Neural Networks and Applications
- Immune Response and Inflammation
- Smart Agriculture and AI
- Metaheuristic Optimization Algorithms Research
- Remote Sensing and LiDAR Applications
- NF-κB Signaling Pathways
- Advanced Vision and Imaging
- Remote Sensing in Agriculture
- Receptor Mechanisms and Signaling
- Advanced Computational Techniques and Applications
- Fibroblast Growth Factor Research
- COVID-19 and Mental Health
- Folate and B Vitamins Research
- Inflammation biomarkers and pathways
- Elevator Systems and Control
- Time Series Analysis and Forecasting
- RNA regulation and disease
China Construction Bank
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
Chongqing Medical University
2025
Wuhan University
2017-2024
Renmin Hospital of Wuhan University
2017-2024
NARI Group (China)
2024
Donghua University
2016-2023
Memorial Sloan Kettering Cancer Center
2021-2023
Tibet Autonomous Region People's Hospital
2019-2022
Shanghai University
2022
Innate immune receptor signaling, united receptors such as RIG-I, cGAS, and Toll-like bind microbial fragments alert the system to an infection. Each type signals through a different adapter protein. These activate protein kinase TBK1 transcription factor IRF3, which tells cells secrete interferon proteins (IFNs) important for host defense. Liu et al. now report common signaling mechanism used by all three types of innate receptor-adaptor pairs IRF3 generate IFNs. This is because must...
RNA virus infections are detected by the RIG-I family of receptors, which induce type-I interferons through mitochondrial protein MAVS. MAVS forms large prion-like polymers that activate cytosolic kinases IKK and TBK1, in turn NF-κB IRF3, respectively, to interferons. Here we show recruit several TRAF proteins, including TRAF2, TRAF5, TRAF6, distinct TRAF-binding motifs. Mutations these motifs disrupted binding TRAFs abrogated its ability IRF3. IRF3 activation was also abolished cells...
ObjectiveTo examine the psychological distress and associated predictor factors of 2019 corona-virus disease (COVID-19) on survivors in early convalescence Shenzhen.MethodA survey questionnaire consisting post-traumatic stress disorder self-rating scale (PTSD-SS), depression (SDS), anxiety (SAS) was presented to COVID-19 still quarantine. Scores each subscale were dependent variables Mann-Whitney test stepwise regression analysis.ResultsA total 126 subjects included study, mean scores...
Pathogen infection and tissue injury are universal insults that disrupt homeostasis. Innate immunity senses microbial infections induces cytokines/chemokines to activate resistance mechanisms. Here, we show that, in contrast most pathogen-induced cytokines, interleukin-24 (IL-24) is predominately induced by barrier epithelial progenitors after independent of microbiome or adaptive immunity. Moreover, Il24 ablation mice impedes not only epidermal proliferation re-epithelialization but also...
Data-driven soft sensors, estimating the pivotal quality variables, have been widely employed in industrial process. This paper proposes a novel sensor modeling approach based on two-stream λ gated recurrent unit (T S - GRU) network. First, factors <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> and xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> are implemented to alter linear constraint existing original GRU unit, enriching...
Nowadays, 3D imaging of plants not only contributes to monitoring and managing plant growth, but is also becoming an essential part high-throughput phenotyping. In this paper, inexpensive (less than 70 USD) portable platform with binocular stereo vision established, which can be controlled by a laptop. the matching step, efficient cost calculating measure—AD-Census—is integrated adaptive support-weight (ASW) approach improve ASW’s performance on real images. quantitative assessment, our...
Automatic leaf segmentation, as well identification and classification methods that built upon it, are able to provide immediate monitoring for plant growth status guarantee the output. Although 3D point clouds contain abundant phenotypic features, leaves usually distributed in clusters sometimes seriously overlapped canopy. Therefore, it is still a big challenge automatically segment each individual from highly crowded canopy phenotyping purposes. In this work, we propose an...
The chronic rejection responses and side effects of the systematic administration immunosuppressants are main obstacles to heart allograft patient survival. development xenotransplantation also urgently requires more efficient immune regulation strategies. Herein, it is demonstrated that lymph-node (LN)-targeted drug delivery can realize LN-specific immunomodulation with attenuated suppression on distant peripheral organs effectively prolong long-term survival after transplantation in a...
Abstract- Computing power, integrating computation, network transport, and data storage, represents a new productivity paradigm. As AI models evolve, the demand for computing power intensifies, particularly within financial centers. However, traditional resources are often underutilized due to inadequate management, leading significant waste. This article proposes architecture optimization managing heterogeneous chip optimizing distributed algorithm training, enhancing resource utilization...
<title>Abstract</title> <bold>Purpose</bold>: The relationship between vitamin B12, methylmalonic acid (MMA, a marker of B12 deficiency), and mortality among stroke survivors remains unclear. This study investigates the association serum MMA levels with in survivors. <bold>Methods: </bold>This prospective cohort study, part NHANES, included adults who experienced 1999-2004 2011-2014, followed until December 31, 2019. We analyzed levels, dietary intake, supplement use. Three weighted Cox...
Leaves account for the largest proportion of all organ areas most kinds plants, and are comprise main part photosynthetically active material in a plant. Observation individual leaves can help to recognize their growth status measure complex phenotypic traits. Current image-based leaf segmentation methods have problems due highly restricted species vulnerability toward canopy occlusion. In this work, we propose an approach dense plant point clouds using facet over-segmentation region...
In recent years, with the development of machine learning, especially after rise deep time series clustering has been proven to effectively provide useful information in cloud computing and big data. However, many modern algorithms are difficult mine complex features series, which is important for further analysis. Convolutional neural network provides powerful feature extraction capabilities excellent performance classification tasks, but it hard be applied clustering. Therefore, a...
Relation extraction is an important task of information extraction. Most existing methods Chinese language relation are based on word input. They highly dependent the quality segmentation and suffer from ambiguity polysemic words. Therefore, a multi-feature fusion model presented basis character input, which integrates character-level features, word-level features entity sense into deep neural network models. Specifically, to alleviate polysemy, introduced as external knowledge provide...