A5000244410- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Acute Ischemic Stroke Management
- Vascular Malformations Diagnosis and Treatment
- Meningioma and schwannoma management
- Artificial Intelligence in Healthcare and Education
- Cerebrovascular and Carotid Artery Diseases
- Machine Learning in Healthcare
- Inflammatory Biomarkers in Disease Prognosis
- Neurofibromatosis and Schwannoma Cases
- Brain Metastases and Treatment
- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
- S100 Proteins and Annexins
- Cardiovascular and Diving-Related Complications
- Obstructive Sleep Apnea Research
- Glioma Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Palliative Care and End-of-Life Issues
- Facial Nerve Paralysis Treatment and Research
Unfallkrankenhaus Berlin
2022-2025
University Hospital Bonn
2020-2022
University of Bonn
2015-2022
Given the ongoing global SARS-CoV-2-vaccination efforts, clinical awareness needs to be raised regarding possibility of an increased incidence SARS-CoV-2-vaccine-related immune-mediated thrombocytopenia in patients with intracerebral hemorrhage (ICH) secondary cerebral sinus and vein thrombosis (CVT) requiring (emergency) neurosurgical treatment context vaccine-induced immune thrombotic (VITT). Only recently, association vaccinations has been described. In a number cases, is warranted for...
OBJECTIVE Cavernoma-related epilepsy (CRE) is a frequent symptom in patients with cerebral cavernous malformations (CCMs). Reports on surgical management and seizure outcome of epileptogenic CCM often focus intracranial cavernoma general. Therefore, data CCMs within the temporal lobe are scarce. The authors therefore analyzed their institutional data. METHODS From 2003 to 2018, 52 suffering from located underwent surgery for CRE at University Hospital Bonn. Information patient...
In aneurysmal subarachnoid hemorrhage (SAH) and multiple intracranial aneurysms (MIAs) identification of the bleeding source cannot always be assessed according to pattern. Therefore, we developed a statistical model for prediction ruptured aneurysm in patients with SAH potential sources at time ictus.Between 2012 2015, 252 harboring 619 were admitted authors' institution. Patients followed prospectively. Aneurysm patient characteristics, as well radiological findings entered into...
Object: Inflammatory response is an important determinant of subsequent brain injury after deep-seated intracerebral hemorrhage (ICH). The ratio red blood cell (RBC) distribution width to platelet count (RPR) has been established as a new index reflect the severity inflammation. To best our knowledge, no association between RPR and prognosis spontaneous ICH yet reported. Methods: In all patients with treated at Neurovascular Center from 2014 2020, initial laboratory values were obtained...
While management of patients with deep-seated intracerebral hemorrhage (ICH) is well established, there are scarce data on ICH who require prolonged mechanical ventilation (PMV) during the course their acute disease. Therefore, we aimed to determine influence PMV mortality in and identify associated risk factors. From 2014 May 2020, all were admitted intensive care for >3 days included further analyses. defined as receiving more than 7 days. A total 42 out 94 (45%) suffered from...
Objective: Tumor-associated proptosis comprises a frequent phenomenon that negatively impacts quality of life in patients suffering from spheno-orbital meningioma (SOM). Therefore, outcome represents an important measure surgery. In the current study, we analyzed our institutional database order to evaluate recovery tumor-associated with SOM. Methods: Between 2009 and 2019, 32 SOM underwent surgical treatment at authors' institution. The exophthalmos index (EI) was calculated by means...
Background/Aim: Older patients are considered to bear a higher perioperative risk. Since idiopathic normal pressure hydrocephalus (NPH) predominantly concerns older patients, identifying risk factors for early shunt failure preoperative risk/benefit assessment is indispensable indication and/or consultation of ventriculoperitoneal shunting (VPS). Methods: We performed retrospective study design, including data acquired from two university hospital neurosurgical institutions between 2012 and...
Intracerebral hemorrhage (ICH) is a frequently disabling or fatal disease. The localization of ICH often allows an etiological association. However, in atypical/lobar ICH, the cause bleeding less obvious. Therefore, we present prospective histopathological and radiological studies which were conducted within diagnostic workup to identify causes for lobar other than hypertension. From 2016 2018, 198 patients with spontaneous, non-traumatic requiring neurosurgical monitoring enrolled...
Acute kidney injury (AKI) is a known predictor of unfavorable outcome in patients treated at the ICU, irrespective disease. However, data on potential influence serum creatinine (sCr) hospital admission suffering from aneurysmal subarachnoid hemorrhage (SAH) scarce. A total 369 consecutive SAH were included this retrospective cohort study. Patients divided into good-grade (WFNS I−III) versus poor-grade IV−V). Outcome was assessed according to modified Rankin Scale (mRS) after 6 months and...
(1) Background: As elements of the standard admission blood panel, lactate and glucose represent potential biomarkers for outcome prediction. In patients with intracranial hemorrhage (ICH), data on predictive value these values is exceedingly sparse. (2) Methods: Between 2014 August 2020, all deep-seated ICH referred to neurovascular center at authors’ institution were included in subsequent study. Serum levels time compared mortality 90 days. addition, a multivariate analysis was performed...
Objective: There remains a significant risk of chronic subdural hematoma (CSDH) recurring after treatment. Patient-related predictors and surgical procedures have been investigated in many studies. In contrast, the literature scant on reports potential impact dehydration admission affected patients CSDH recurrence rate. Methods: All consecutively admitted with treatment at authors’ institution between 2015 2019 were retrospectively identified. Dehydration was assessed as blood...
Obstructive sleep apnea is a risk factor for hypertension. Hypertension associated with aneurysm formation, growth, and rupture of intracranial (IA). Retrospectively, symptoms obstructive are more prevalent in patients IAs. Studies investigating the prevalence effect objectively measured these sparse. We report on baseline data an ongoing prospective study. cross-sectionally analyzed whether was larger IAs increased need antihypertensive medications population unruptured IA.130 adult (≥ 18...
The impact of dehydration at admission patients with spontaneous intracerebral hemorrhage (ICH) on short-term mortality remains ambiguous due to scarce data. All the consecutive ICH, who were referred our neurovascular center in 2018/19, assessed for hydration status admission. Dehydration was defined by a blood urea-to-creatinine ratio > 80. In cohort 249 patients, 76 (31%) dehydrated time following factors significantly and independently associated increased 30-day multivariate...
The aim was to evaluate hospitalization rates for aneurysmal subarachnoid hemorrhage (SAH) within an interdisciplinary multicenter neurovascular network (NVN) during the shutdown COVID-19 pandemic along with its modifiable risk factors. In this study, admission SAH were compared period of in Germany (calendar weeks (cw) 12 16, 2020), periods before (cw 6-11) and after 17-21 22-26, as well corresponding cw years 2015-2019. Data on all-cause pre-hospital mortality area NVN retrieved from...