A5024941898- Drug Solubulity and Delivery Systems
- Granular flow and fluidized beds
- Cyclone Separators and Fluid Dynamics
- Microencapsulation and Drying Processes
- Advanced Drug Delivery Systems
- Protein purification and stability
- Material Properties and Processing
- 3D Printing in Biomedical Research
- Aerosol Filtration and Electrostatic Precipitation
- Analytical Methods in Pharmaceuticals
- Additive Manufacturing and 3D Printing Technologies
- Particle Dynamics in Fluid Flows
- Pharmaceutical studies and practices
- Crystallization and Solubility Studies
- Powder Metallurgy Techniques and Materials
- Inhalation and Respiratory Drug Delivery
- Injection Molding Process and Properties
- Analytical Chemistry and Chromatography
- Advancements in Transdermal Drug Delivery
- Mineral Processing and Grinding
- Fluid Dynamics and Heat Transfer
- Tribology and Lubrication Engineering
- Image Processing Techniques and Applications
- Electrohydrodynamics and Fluid Dynamics
- Spectroscopy and Chemometric Analyses
University of Ljubljana
2015-2025
Ljubljana Passenger Transport
2023
Heinrich Heine University Düsseldorf
2016-2017
Graduate School Experimental Plant Sciences
1984-1985
Objective: The purpose of this study was to investigate and quantify flow properties, compressibility, compactibility various pharmaceutical lactose powders found on the market today (DCL-11, DCL-21, M‐200, Flowlac-100, Tablettose 70, 80, 100). Methods: Flow properties were estimated by measuring time, angle repose, Hausner ratio. Particle rearrangement studied using Kawakita's linear model. Compressibility two 'out-of-die' methods: (i) Heckel model (ii) a modified Walker Compactibility...
Binder jetting has the potential to revolutionize way we produce medicine. However, tablets produced by binder technology can be quite fragile and hard handle. In this study, printing process ink composition were examined optimize mechanical properties of tablets. A model formulation containing ketoprofen drug was developed used as a base for optimization. Firstly, important parameters identified with fractional factorial design. Saturation layer height critically influenced selected tablet...
In this study, different modifications of bottom spray fluid-bed coater with draft tube inserted were characterized and evaluated.After coating the neutral pellets polymeric solution comprising coloring agent pellet batches for variation, yield degree agglomeration.Funnel-shaped distribution plate was found to improve process decrease agglomeration at selected values parameters, whereas uniformity worse in all cases when compared conventional Wurster chamber. Results chamber swirl airflow...
This study evaluated the performance of two bottom-spray coaters and effect pellet-size variability on coating uniformity. A conventional Wurster chamber was used for first group trials, a with novel swirl-flow generator design second. The results confirmed that when using chamber, pellets smaller diameter receive significantly less material compared to those larger diameters. swirl generator-equipped achieved close uniform thickness regardless pellet size. ratio (MS) mass dye deposited in...
The aim of this work is to use an experimental design approach identify and study influential formulation delivery device properties, which can be controlled by final product manufacturer, establish space, within desired in vitro performance reached.Combining three factors, viscosity suspension, nozzle orifice diameter (OD), shot weight (SW), at levels resulted D-optimal with 20 runs. Responses were droplet size distribution (DSD) spray pattern (SP) tests. In addition, the amount mechanical...