Objectives To evaluate the efficacy of a municipality‐led walking program under Japanese public Long‐Term Care Insurance Act to prevent mental decline. Design Randomized controlled trial. Setting The city T akasaki. Participants One hundred fifty community members aged 72.0 ± 4.0 were randomly divided into intervention (n = 75) and control groups. Intervention A was conducted once week for 90 minutes 3 months. encouraged participants walk on regular basis increase their steps per day...

To investigate factors associated with caregiver burden (CB) in persons caring for older adults various cognitive stages of Alzheimer's disease (AD).Participants were 1127 outpatients and their caregivers. Participants comprised 120 normal cognition (NC), 126 amnestic mild impairment (aMCI) 881 AD. AD patients subclassified into four groups by Mini-Mental State Examination (MMSE) score: AD29-24 (n = 117), AD23-18 423), AD17-12 254) AD11-0 87). caregivers underwent comprehensive geriatric...

Abstract Purpose The aim of this study was to evaluate the impact memory complaints on quality life ( QOL ) in elderly community dwellers with or without mild cognitive impairment MCI ). Methods Participants included 120 normal controls NC and 37 aged 65 over. measured using Japanese version Satisfaction Daily Life, were a questionnaire consisting four items. relevance evaluated psychological factors personality traits, sense self‐efficacy, depressive mood, self‐evaluation daily functioning,...

The purpose of this study was to evaluate the deficits metaphor and sarcasm comprehension in Alzheimer’s disease (AD), as pragmatic interpretation such is required social communication. A total 31 young normal controls, 104 aged controls (ANC), 42 patients with amnesic mild cognitive impairment (aMCI), 30 AD were evaluated by Metaphoric Sarcastic Scenario Test, which consists 5 metaphoric sarcastic questions answer choices. Scores analyzed using repeated measures analysis variance...

We aimed to study how patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) suffer from awareness of their deficits. Self-awareness was assessed using the Anosognosia Questionnaire for Dementia in 12 pairs MCI outpatients caregivers, 23 AD, 18 moderate AD. The discrepancy between patient’s caregiver’s evaluation (anosognosia) became greater as AD progressed. predictors patients’ distress, shown by multiple linear regression analyses, were decline intellectual or social...

Aim To examine the efficacy of rehabilitation for elderly individuals with dementia at intermediate facilities between hospitals and home, based on policies to promote community‐based care home dehospitalization. Methods Participants were older adults newly admitted facilities. A total 158 in intervention group who claimed L ong‐ T erm C are I nsurance three consecutive months, 54 control included analysis. The interventions carried out a tailor‐made manner meet individual needs. personal...

ABSTRACT Background: Positivity recognition bias has been reported for facial expression as well memory and visual stimuli in aged individuals, whereas emotional Alzheimer disease (AD) patients is controversial, with possible involvement of confounding factors such deficits spatial processing non-emotional features verbal to express emotions. Thus, we examined whether positive expressions was preserved AD patients, by adapting a new method that eliminated the influences these factors....

Although affective and/or attention modulation of somatosensory processing has been well studied, the biological bases somatic symptoms in patients with major depressive disorder (MDD) have rarely examined. To elucidate changes underlying MDD, we conducted a magnetoencephalography study MDD and healthy controls.After median nerve stimulation, evoked fields (SEF) were recorded 10 sex-, age-, height-matched volunteers under attending, visually non-attending conditions. The latencies magnitudes...

<b><i>Background/Aims:</i></b> We aimed to prove the effectiveness of brain-activating rehabilitation for dementia, which consisted 5 principles: pleasant atmosphere, communication, praising, social role, and supportive care. <b><i>Methods:</i></b> The design was a randomized controlled trial that not blinded. Fifty-four elderly participants with dementia (mean age: 85.2 years) were selected. Intervention based on principles conducted 1 h,...

Aim: Japan is one of the most rapidly aging societies in world. Measures to prevent dementia are urgently required Japan, although such strategies have not yet been established. This study investigated effectiveness a pleasant physical exercise intervention on prevention cognitive decline community‐dwelling elderly participants with subjective memory complaints. In this intervention, atmosphere was emphasized enhance participants' motivation. Method: We administered 12‐week program...

We herein propose a hand-gesture imitation test, consisting of simple one-handed sign 'fox' and complex two-handed 'pigeon', as rapid, game-like test for detecting dementia/Alzheimer disease (AD) with low psychological burden. The measures the visuomotor function, which deteriorates in early stages AD.We examined 88 demented subjects, 19 mild cognitive impairment (MCI), 53 normal controls aged 65 years or over. subjects were classified according to Clinical Dementia Rating (CDR).The...

Abstract Background: To prepare for a super‐aging society, effective dementia screening tests are required. The most salient deficit appearing from the early stages of dementia/Alzheimer's disease (AD) is deterioration in memory. Hasegawa Dementia Scale‐revised (HDS‐R) and Mini‐Mental State Examination (MMSE) widely used Japan to screen dementia. Both place an emphasis on memory function, but neither examines visuo‐spatial (VSM) even though VSM deficits sensitive marker detection conversion...

The aim of this study was to develop a brief informant-based questionnaire, namely the Symptoms Early Dementia-11 Questionnaire (SED-11Q), for screening early dementia. 459 elderly individuals participated, including 39 with mild cognitive impairment in Clinical Dementia Rating scale (CDR) 0.5, 233 dementia CDR 1, 106 moderate 2, and 81 normal controls 0. Informants were required fill out 13-item questionnaire. Two items excluded after analyzing sensitivities specificities. final version...

ABSTRACT Background: In Alzheimer's disease (AD) patients, deficits in contextual understanding and intentions/beliefs of other people (theory mind; ToM) cause communication problems between patients caregivers. To evaluate understanding/ToM, we developed the Pitfall Intention Explanation Task with Clue Questions (Pitfall task). Methods: We recruited 26 healthy older adults clinical dementia rating (CDR) 0, 62 outpatients: 12 amnestic mild cognitive impairment (aMCI) CDR 0.5; 36 AD 1; 14...

The objective is to propose a brief method evaluate anosognosia in Alzheimer's disease (AD) using the Symptoms of Early Dementia-11 Questionnaire (SED-11Q), short informant-based screening questionnaire for identifying dementia.The participants were 107 elderly individuals: 13 with Clinical Dementia Rating (CDR) 0.5, 73 mild AD CDR 1, and 21 moderate 2. patients caregivers answered SED-11Q independently, degree discrepancy indicated severity anosognosia.THE SCORES WERE AS FOLLOWS: caregiver...

Abstract Background: In out‐patient clinics, having simple procedures to check for signs of dementia is invaluable. the present study, we evaluated imitation hand gestures detect visuomotor deficits in clinical practice. Methods: all, 1219 subjects were enrolled including 497 with Alzheimer's disease (AD), 98 Lewy bodies (DLB), 71 other types diseases, 175 a Clinical Dementia Rating (CDR) 0.5, and 378 normal controls. All aged 65 years or older. Subjects recruited from 10 clinics two...

Communicative disability is regarded as a prominent symptom of demented patients, and many studies have been devoted to analyze deficits lexical-semantic operations in patients. However, it often observed that even patients with preserved skills might fail interactive social communication. Whereas interaction requires pragmatic language skills, competencies subjects not well understood. We propose here brief stress-free test detect deficits, focusing on non-literal understanding figurative...

ABSTRACT Background: Theory of Mind reasoning, which plays a pivotal role in social interaction, is required to detect deception. Empirically, those with cognitive decline are vulnerable Methods: Participants were 45 healthy elderly adults clinical dementia rating (CDR) 0, and 76 outpatients: 25 amnestic mild impairment (aMCI, CDR 0.5), 34 Alzheimer's disease (ADD, 1), 17 moderate ADD (CDR 2). The task consisted two single-frame cartoons that depicted character an intention deceive another...

Ikigai is a Japanese concept, meaning "a reason for being," and having ikigai, or purpose in life, has been shown to contribute dementia prevention healthy longevity. Primary efforts stop the occurrence of have focused on multimodal lifestyle interventions, including nutritional guidance, exercise, cognitive training, control vascular risk factors, with little research psychological interventions. Conversely, rehabilitation programs prevent progression involved various interventions as focus...