A5018058878- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cervical and Thoracic Myelopathy
- Scoliosis diagnosis and treatment
- Nutrition and Health in Aging
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Musculoskeletal pain and rehabilitation
- Body Composition Measurement Techniques
- Renal Diseases and Glomerulopathies
- Diabetic Foot Ulcer Assessment and Management
- Spinal Hematomas and Complications
- Cerebral Palsy and Movement Disorders
- Anesthesia and Pain Management
- Stroke Rehabilitation and Recovery
- Balance, Gait, and Falls Prevention
- Pelvic and Acetabular Injuries
- Aortic Disease and Treatment Approaches
- Vascular Procedures and Complications
- Spinal Dysraphism and Malformations
- Botulinum Toxin and Related Neurological Disorders
- Advanced Radiotherapy Techniques
- Cardiac Valve Diseases and Treatments
- Frailty in Older Adults
Shizuoka General Hospital
2008-2025
Prefectural University of Hiroshima
2014-2025
Rikkyo University
2021-2024
Shinshu University
2024
Ogikubo Hospital
2024
Tokyo Women's Medical University
1996-2023
Gunma Prefectural Cardiovascular Center
2023
Nagano Red Cross Hospital
2023
Nagoya University
2014-2021
Saiseikai Fukuoka General Hospital
2021
Objectives To evaluate the efficacy of a municipality‐led walking program under Japanese public Long‐Term Care Insurance Act to prevent mental decline. Design Randomized controlled trial. Setting The city T akasaki. Participants One hundred fifty community members aged 72.0 ± 4.0 were randomly divided into intervention (n = 75) and control groups. Intervention A was conducted once week for 90 minutes 3 months. encouraged participants walk on regular basis increase their steps per day...
Human pluripotent stem cells (hPSCs) are being applied in regenerative medicine and for the vitro modeling of human intractable disorders. In particular, neural derived from disease-specific induced (hiPSCs) established patients with neurological disorders have been used as disease models to recapitulate vivo pathogenesis because cannot be usually obtained themselves. this study, we a rapid, efficient, simple method efficiently deriving motor neurons hPSCs that is useful pathophysiological...
Our aim of this study is to compare the thigh muscle thickness measurements obtained using ultrasound and bioelectrical impedance analysis (BIA) methods, investigate validity cutoff value ultrasonography. We analyzed a total 201 participants (99 male 102 female participants, mean age, 66.2 years) participated in annual health checkup Yakumo Study, 2014. Thigh (TMT, sum rectus femoris vastus intermedius thickness) was measured at mid-thigh sitting position. Appendicular skeletal mass (aSMI)...
The phase angle, which is measured via bioelectrical impedance analysis (BIA), a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases, such as locomotive syndrome (LS). It remains unclear if angle associated with frailty (fragile state physical mental health). We therefore examined this association in large prospective sample. Of 1081 individuals receiving health checkups, 550 (male; 235, female; 365) were enrolled study....
Abstract Background Despite recent advances in immunosuppressive therapy for patients with primary nephrotic syndrome, its effectiveness and safety have not been fully studied nationwide real-world clinical data Japan. Methods A 5-year cohort study, the Japan Nephrotic Syndrome Cohort Study, enrolled 374 syndrome 55 hospitals Japan, including 155, 148, 38, 33 minimal change disease (MCD), membranous nephropathy (MN), focal segmental glomerulosclerosis (FSGS), other glomerulonephritides,...
✓The response of nonfluorescing infiltrating tumors that had been exposed to 5–aminolevulinic acid and irradiated using a laser at wavelength 405 nm was analyzed intraoperatively spectroscopy. Histological analyses demonstrated neoplastic cells were present in the tissue region displayed peak 636 nm, whereas no exhibited only excitation light peak. The authors conclude intraoperative use spectroscopy can allow diagnosis tumor detection boundaries infiltrate when standard fluorescence techniques fail.
Objectives: To investigate the severity and effect on quality of life (QOL) various types pain in healthy volunteers.Methods: A total 384 subjects (male: 158, female: 226, average age: 63 years) were included a prospective cohort study (Yakumo study). Shoulder pain, low back (LBP), sciatica, knee American Elbow Surgeons (ASES) shoulder score evaluated with SF-36.Results: The prevalence LBP, was 42%, 44%, 16%, 48%, respectively, similar severities pain. visual analogue scale (VAS) ASES scores...
Thoracic ossification of the posterior longitudinal ligament (T-OPLL) is treated surgically with instrumented decompression and fusion. However, factors determining outcome this approach efficacy additional resection T-OPLL are unknown.To identify these in a prospective study at single institution.The subjects were 70 consecutive patients beak-type who underwent dekyphotic fusion had an average 4.8 years follow-up (minimum 2 years). Of patients, 4 (6%; group R) no improvement or aggravation,...
This study was designed to evaluate whether changes in lifestyle behaviors are correlated with the incidence of chronic kidney disease (CKD).The subjects consisted 316 men without a history cardiovascular disease, stroke, or renal dysfunction dialysis treatment. The following were evaluated using standardized self-administered questionnaire: habitual moderate exercise, daily physical activity, walking speed, eating late-night dinner, bedtime snacking, skipping breakfast, and drinking smoking...
Study Design. A prospective cohort study. Objective. This study aimed to investigate the relationship between preoperative cervical sagittal alignment and postoperative kyphosis in patients with spondylotic myelopathy (CSM) determine cut-off angle for predicting postlaminoplasty kyphosis. Summary of Background Data. There have been several reports describing a after laminoplasty. However, there has no on large series CSM. Methods. total 1025 consecutive CSM (642 men 383 women; mean age, 64.4...
Abstract Purpose Sodium-glucose cotransporter 2 inhibitors (SGLT2is) are commonly prescribed anti-diabetic medications with various beneficial effects; however, they have also been associated ketoacidosis. The aim of this study was to determine the incidence SGLT2i-associated perioperative ketoacidosis (SAPKA) in surgical patients. Methods We conducted a multicenter, prospective cohort across 16 centers Japan, enrolling patients diabetes who were SGLT2is between January 2021 and August 2022....
Study Design. Retrospective multicenter study. Objective. The goal of this study is to determine the characteristic imaging features spinal ependymoma in a review magnetic resonance (MRI) data for large series surgically proven cases. Summary Background Data. Common intramedullary neoplasms are mostly ependymomas and comprise 50% 60% neuroepithelial tumors adults. Preoperative prediction pathological diagnosis could enhance surgical planning explanation procedure patients. However, these...
Study Design Prospective clinical study. Objective Posterior decompression and fusion surgery for beak-type thoracic ossification of the posterior longitudinal ligament (T-OPLL) generally has a favorable outcome. However, some patients require additional postoperative severe paralysis, condition that is inadequately discussed in literature. The objective this study was to describe efficacy procedure we refer as "resection at an anterior site spinal cord from approach" (RASPA) severely...
Spinal fusion and bone defect after injuries, removal of tumors, infections need to be repaired by implantation. In an aging society, recovery from these procedures is often difficult. this study, we found that injection SPG-178 leads expression several marker genes mineralization in vitro, revealed a significantly higher degree newly formed matrix with use vivo. MC3T3-E1 cells were used evaluate osteoblast differentiation promoted SPG-178. To analyze gene expression, total RNA was isolated...
Purpose: To identify differences between locomotive syndrome (LS) and frailty.Methods: A total of 1016 subjects (males 427, females 589, mean age 64 years) were prospectively examined in the Yakumo study. LS was defined as ≥16 on GLFS-25 questionnaire. Frailty diagnosed ≥3 unintentional weight loss, grip strength weakness, low walking speed, exhaustion, physical activity.Results: (14.4%) frailty (10.8%) more significant older, female with weaker muscle strength, lower gait severer pain,...
Prospective study.Investigate factors associated with preoperative motor paresis, recovery, ambulatory status, and intraoperative neurophysiological monitoring (IONM) among patients no paresis (N group), complete recovery (CR (NCR group) in intramedullary spinal cavernous hemangioma to determine the optimal timing of surgery.The study evaluated 41 surgical cases our institute. Disease duration, tumor lesion, manual muscle testing (MMT), gait at onset, just before surgery, final follow-up...
Locomotive syndrome (LS) is a condition requiring nursing care for musculoskeletal disorders. Our aim was to evaluate the correlation between body composition, measured by bioelectrical impedance analysis (BIA), and LS, using 25-question Geriatric Functional Scale (GLFS-25).We enrolled 286 individuals who were undergoing regular health follow-up. All completed GLFS-25, composition BIA, five physical performance tests related LS: timed up-and-go test, 10-m gait time, maximum stride length,...