A5103051441- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Viral Infections and Vectors
- Influenza Virus Research Studies
- HIV Research and Treatment
- Animal Disease Management and Epidemiology
- Adolescent Sexual and Reproductive Health
- Tuberculosis Research and Epidemiology
- HIV/AIDS drug development and treatment
- Viral gastroenteritis research and epidemiology
- Fire effects on ecosystems
- Vector-borne infectious diseases
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Vector-Borne Animal Diseases
- Pediatric health and respiratory diseases
- Mosquito-borne diseases and control
- Pneumocystis jirovecii pneumonia detection and treatment
- Sex work and related issues
- COVID-19 epidemiological studies
- Infectious Diseases and Tuberculosis
- Bartonella species infections research
- Syphilis Diagnosis and Treatment
- HIV-related health complications and treatments
- SARS-CoV-2 and COVID-19 Research
Zhejiang Center for Disease Control and Prevention
2015-2025
Beijing Institute of Technology
2024
Fudan University
2022
Academia Sinica
2016
Chinese Academy of Medical Sciences & Peking Union Medical College
2016
University of Chinese Academy of Sciences
2016
BGI Group (China)
2016
University of Hong Kong
2014-2016
Wenzhou Medical University
2016
Hangzhou Center for Disease Control and Prevention
2014-2016
The first identified cases of avian influenza A(H7N9) virus infection in humans occurred China during February and March 2013. We analyzed data obtained from field investigations to describe the epidemiologic characteristics H7N9 as December 1, 2013.Field were conducted for each confirmed case infection. A patient was considered have a if presence verified by means real-time reverse-transcriptase-polymerase-chain-reaction assay (RT-PCR), viral isolation, or serologic testing. Information on...
Abstract Closure of live poultry markets was implemented in areas affected by the influenza virus A(H7N9) outbreak China during winter, 2013–14. Our analysis showed that closing most cities Guangdong and Zhejiang provinces highly effective reducing risk for H7N9 infection humans.
Background Continuously growing of HIV incidence among men who have sex with (MSM), as well the low rate testing MSM in China, demonstrates a need for innovative strategies to improve implementation prevention. The use machine learning algorithms is an increasing tendency disease diagnosis prediction. We aimed develop and validate models predicting infection that can identify individuals at increased risk acquisition transmission-reduction interventions. Methods extracted data from sentinel...
Abstract Background/objective People living with HIV (PLWH) are prone to mental health problems and evidence indicates that HIV-related stigma can negatively impact health-related quality of life. This study explored potential mechanisms between life, specifically whether anxiety or depression mediates, social support moderates, the relationship. Method A total 1197 Chinese PLWH participated in study. The Berger Stigma Scale, Hospital Anxiety Depression Scale (HADS), 12-item Brief Health...
ObjectivesTo summarize the epidemiological characteristics of severe fever with thrombocytopenia syndrome (SFTS) in Zhejiang Province, China.MethodsA standardized questionnaire was used to collect information on demographic features, exposure history, clinical symptoms, and timelines medical visits. Descriptive statistics were analyze SFTS.ResultsA total 65 cases SFTS identified Province from 2011 2013, whom 34 male 31 female. The median age 66 years 60 occurred persons aged ≥50 years....
Tick species distribution and prevalence of spotted fever group Rickettsiae (SFGR) in ticks were investigated Zhejiang Province, China 2010 2011. PCR was used to detect SFGR positive amplicons sequenced, compared published sequences phylogenic analysis performed using MEGA 4.0. A total 292 adult ten captured 7.5 % (22/292) the PCR-positive for SFG Rickettsia. The rates 5.5 (6/110) Haemaphysalis longicornis, 3.6 (1/28) Amblyomma testudinarium 16 (15/94) Ixodes sinensis, respectively....
Background Men who have sex with men (MSM) constitute a significant population of patients infected HIV. In recent years, several efforts been made to promote HIV testing among MSM in China. Objective This study aimed assess coverage and factors associated first-time provide scientific basis for achieving the goal diagnosing 95% by 2030. Methods cross-sectional was conducted between July 2023 December 2023. were recruited from “Sunshine Test,” an internet platform that uses location-based...
A novel influenza virus infection was identified on March 31, 2013 in China and a total of 134 cases were 12 provinces between 25 September 2013. Of these, 46 occurred Zhejiang Province the number patients is largest China. Field investigations conducted for each confirmed H7N9 case. standardized questionnaire used to collect information about demographics, exposure history, clinical signs symptoms, timelines medical visits care after onset illness, close contacts. Descriptive statistics...
Post-translational modifications of histones are significant regulators replication, transcription, and DNA repair. Particularly, newly synthesized histone H4 in H3/H4 heterodimers becomes acetylated on N-terminal lysine residues prior to its incorporation into chromatin. Previous studies have established that the acetyltransferase (HAT) complex Hat1p/Hat2p medicates this modification. However, mechanism how recognizes facilitates enzymatic activities assembled heterodimer remains unknown....
Abstract Tuberculosis, a severe infectious disease caused by the Mycobacterium tuberculosis, arouses huge concerns globally. In this study, total of 331,594 TB cases in Zhejiang Province were notified during period 2009–2018 with gender ratio male to female 2.16:1. The incidences demonstrated continuously declining trend from 75.38/100,000 52.25/100,000. Seasonally, presented as low January and February closely followed an apparent rise March April. Further stratification analysis both...
In this study, we conducted a detailed molecular epidemiological analysis of HIV-1 epidemic strains in various sexual risk behaviour groups developed area eastern China based on phylogenetic inference, transmission networks, and Bayesian analyses. A total 1083 pol sequences (91.23%, 1083/1187) from newly diagnosed HIV-1-positive patients 2017 to 2020 were successfully obtained involved thirteen subtypes, which the major subtypes CRF07_BC (36.10%, 391/1083) CRF01_AE (34.63%, 375/1083). 485...
Objective: To understand the prevalence of psychoactive substance use and related factors in men who have unprotected sex with Zhejiang Province. Methods: Men were recruited by snowball sampling through (MSM) social organization to conduct a cross-sectional investigation from January 2022 December 2023. The sample size was estimated be 1 169 individuals. information about their socio-demographic information, sexual behaviors, use, HIV testing collected on-site questionnaire survey. Logistic...
Effective management of people living with HIV (PLWH) can block the sexual transmission as there is a zero risk (by U=U campaign); however, few studies have aimed to addressed among PLWH in China. We conducted cross-sectional survey 2022. were categorized into four groups: on antiretroviral therapy (ART) and viral load (VL) < 50 copies/mL minimum risk; ART ≤ VL 1,000 low-risk; ≥ copies/mL, or but without testing medium-risk; not high-risk. Multivariable logistic regression was used identify...
This study aimed to establish a collaborative approach quantify local HIV transmission, which is an issue of great concern public health.We linked HIV-1 pol gene sequences demographic information and epidemiological investigations in Hangzhou (a central city East China). We estimated acquisition rates from collaboration molecular network analysis (with distance-based approach) investigations.Among 1064 newly diagnosed patients with HIV, 857 were acquired subsequently analyzed. Multiple...
Background China has recently implemented a strategy to promote and facilitate community organization involvement in HIV prevention among men who have sex with (MSM). Although community-based strategies been shown increase testing uptake, the relative effectiveness of mobile social media promotion compared volunteer-driven recruitment remains underexplored. Limited research investigated how these differentially affect MSM not undergone previous testing. Objective This study aimed compare...
Transition metal nitrides are highly valued for their unique properties and diverse applications in coatings, lighting, energy storage. However, achieving two-dimensional (2D) presents a significant challenge due...