To explore the effects of 8-week polarized training (POL), high-intensity interval (HIIT), and threshold (THR) interventions on cardiorespiratory fitness (CRF) untrained healthy young adults. This study recruited 36 adults randomly assigned them to POL, HIIT, THR, or control (CG) groups undergo an intervention. The impulse applied all three intervention was identical. intensity divided into Zone 1, 2, 3 (Z1, Z2 Z3) basis ventilatory thresholds (VT). weekly distribution for POL 75% Z1 25% Z3;...

Abstract Background The prevalence of esophageal neoplasia in head and neck (H&N) cancer patients is not low; however, routine surveillance included staging newly-diagnosed H&N cancers. We aimed to investigate the risk factors for synchronous impact endoscopy on management patients. Methods A total 129 newly diagnosed who underwent with white-light imaging, narrow-band imaging (NBI) magnifying (ME), chromoendoscopy 1.5% Lugol’s solution, before definite treatment were enrolled...

Abstract Activation and expansion of dengue virus‐specific T cells abnormal liver functions in patients have been documented. However, it remains to be determined whether are involved the pathogenic mechanism virus infection. In this study, immunocompetent C57BL/6 mice were employed study virus‐induced cell activation. Mice inoculated with 10 8 PFU serotype 2 strain 16681 by intravenous route. Dengue viral core RNA was detected RT‐PCR mouse serum, liver, spleen, brain at different time...

To investigate the differences in body composition and metabolic syndrome (MS) under a daily 12,000-step strategy with or without moderate-intensity walking exercise college students obesity. Thirty-two adults obesity (mean (s.d.) age: 19.72 (0.80) years; height: 165.38 (3.99) cm; wt: 83.31 (4.66) kg; mass index: 30.38 (0.83) kg m− 2) were recruited randomly assigned to step goal group (WSG; achieving 12,000 steps per day), (WEG; day, including 3 days week on which at rate of over 103 min− 1...

To investigate the mechanism by which resveratrol (Res) ameliorates cognitive impairment (CI) in chronic kidney disease (CKD) rats through modulation of gut microbiota and suppression inflammation. A CKD model was established via two intravenous injections doxorubicin (4 mg/kg, 2 weeks apart). After 8 weeks, renal function histopathological assessments were performed to confirm establishment model.Rats divided into control, CKD, CKD+Res groups. The group received intragastric Res for 6...

To evaluate the experience of induction chemotherapy followed by concurrent chemoradiationwith helical tomotherapy (HT) for nasopharyngeal carcinoma (NPC).Between August 2006 and December 2009, 28 patients with pathological proven nonmetastatic NPC were enrolled. All staged as IIB-IVB. Patients first treated 2 to 3 cycles EP-HDFL (Epirubicin, Cisplatin, 5-FU, Leucovorin). After chemotherapy, weekly based PFL was administered HT. Radiation consisted 70 Gy planning target volumes primary tumor...

Objectives Nasopharyngeal cancer ( NPC ) is an endemic disease in Taiwan. Prognostic factors the anatomical TNM stage are important for its prognostic stratification. An elevated neutrophil‐to‐lymphocyte ratio NLR has been reported to be associated with poor prognosis various solid tumours. In this study, we analysed impact of Design Single‐institution retrospective study. Setting Medical centre. Participants One hundred and eighty patients treated at Far Eastern Memorial Hospital, Taiwan,...

Because hydrogen sulfide (H2S) is classified as a gaseous signaling molecule, protein S-sulfhydration known to be one of the mechanisms by which H2S signals are conducted. PTP1B, negative regulator in insulin signaling, has been found S-sulfhydrated at Cys215-SH form Cys215-SSH response endoplasmic reticulum (ER) stress. Therefore, we aimed understand change PTP1B and cellular redox homeostasis stimulation. We demonstrated feasible PEG-switch method determine levels S-sulfhydration....

Objective To investigate the roles of nitric oxide and adenosine triphosphate (ATP)-sensitive potassium channels (KATP) in shortening cardiac action potential endotoxic shock. Design Prospective animal study with concurrent controls. Setting University research laboratory. Subjects Adult Hartley guinea pigs, weighing 300–400 g. Interventions Guinea pigs were anesthetized mechanically ventilated for 6 hrs. Lipopolysaccharide (LPS) or saline (sham group) given intravenously. Drug effects...

Abstract Background The aim of this study was to assess the treatment results and toxicity profiles helical tomotherapy (HT) for postoperative high-risk oral cavity cancer. Methods From December 6, 2006 through October 9, 2009, 19 cancer patients were enrolled. All received HT with (84%) or without (16%) chemotherapy. Results median follow-up time 17 months. 2-year overall survival, disease-free locoregional control, distant metastasis-free rates 94%, 84%, 92%, respectively. package > 13...

Multiple intracardiac catheters are often necessary for electrophysiological study (EPS) and radiofrequency (RF) ablation therapy. Therefore, multiple venous sheath placement in one femoral vein is always required catheter insertion. The vascular complications incurred by of sheaths have not been fully studied. We utilized duplex ultrasonography to assess the veins before after procedure. This consisted 52 patients (68 veins) who underwent EPS RF Up three were inserted into a single vein....

Synchronous second primary tumors (SPTs), especially esophageal squamous cell neoplasia (ESCN), in patients with head and neck carcinoma (HNSCC) are not uncommon. Image-enhanced endoscopy (IEE) screening may identify SPTs while there is no evidence to support its benefit. We prospectively recruited an adult cohort newly-diagnosed HNSCC for IEE of upper gastrointestinal (UGI) tract neoplasia. 145 were recruited. 22 (15.2%) had synchronous UGI neoplasia, including 20 ESCNs 2 gastric...

The initiation of focal atrial tachycardia (AT) from the superior vena cava (SVC) remains unclear. In 3 patients (2 females, 1 male; aged 57, 66 and 50 years, respectively) with AT arising different parts SVC, occurred spontaneously, rather than being induced by electrical stimulation. cycle length was highly variable, ranging between 190 300 ms in patient 1, 180 320ms 2, 200 300ms 3. clinical or associated arrhythmias were fibrillation (AF) (patients 3) flutter (AFL) 3). A presumed SVC...

In this paper, we exploit the technique of data mining to mine frequent access patterns from user browsing behavior. light patterns, develop a solution procedure automatically extract interests. Furthermore, in accordance with interests mined and feedbacks users, propose new algorithm idea dynamically adjusting ranking scores Web pages. Specifically, PPR (standing for personalized PageRank), is divided into four phases. The first phase assigns initial weights based on second phase, virtual...

We compared the outcome of patients who received non-image-guided intensity-modulated radiotherapy (IMRT) with those helical tomotherapy (HT), a daily image-guided (IGRT), after surgery for oral cavity cancer (OCC).During period November 2006 to December 2013, total 152 postoperative OCC underwent either IMRT (n = 79) or IGRT 73) 4 6 weeks surgery. Patients in group MV photon beams 7 fields and fractions 1.8 2 Gy on five consecutive days.Patients had higher 5-year overall survival than (87%...

Parkinson's disease (PD) is a prevalent movement disorder characterized by mitochondrial dysfunction and dopaminergic neuronal loss in the substantia nigra of midbrain. Currently, there are no effective treatments to cure or slow progression PD, highlighting an urgent need for new therapeutic strategies. Emerging evidence suggests that mesenchymal stem cells (MSCs) fibroblast growth factor 21 (FGF21) potential candidates PD treatment. This study investigates strategy involving FGF21...

In this work, we develop an ultrathin epitaxial h-AlN as interfacial layer (IL) between HfO2 and monolayer WS2 channel by atomic deposition (ALD). The growth of dielectrics using ALD has been challenging due to the dangling-bond-free surface 2D materials. By utilizing sub-1 nm IL depositing high-k dielectric, were able form a uniform atomically flat gate dielectric without voids. resulting structure exhibits equivalent oxide thickness low 1 ultra-low leakage currents ∼10−6 A/cm2. fabricated...