A5058729122- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Plant Gene Expression Analysis
- Plant and Fungal Species Descriptions
- GNSS positioning and interference
- Chronic Lymphocytic Leukemia Research
- Landslides and related hazards
- Plant biochemistry and biosynthesis
- Ionosphere and magnetosphere dynamics
- Acute Myeloid Leukemia Research
- RNA modifications and cancer
- FOXO transcription factor regulation
- Geophysics and Gravity Measurements
- Microtubule and mitosis dynamics
- Nuts composition and effects
- Phytochemicals and Antioxidant Activities
- Geophysical Methods and Applications
- Rock Mechanics and Modeling
- Photosynthetic Processes and Mechanisms
- Dam Engineering and Safety
- Plant Stress Responses and Tolerance
- Plant Taxonomy and Phylogenetics
- PI3K/AKT/mTOR signaling in cancer
- Geophysics and Sensor Technology
- Plant Molecular Biology Research
Jiangxi Academy of Forestry
2013-2025
University of Chinese Academy of Sciences
2021-2024
Chinese Academy of Sciences
2023-2024
Shandong First Medical University
2024
Southwest Petroleum University
2024
Institute of Geodesy and Geophysics
2024
Shandong Provincial Hospital
2024
Collaborative Innovation Center of Chemistry for Energy Materials
2024
Xiamen University
2024
Zhejiang Cancer Hospital
2023-2024
DYRK1A is a serine/threonine kinase encoded on human chromosome 21 (HSA21) that has been implicated in several pathologies of Down syndrome (DS), including cognitive deficits and Alzheimer's disease. Although children with DS are predisposed to developing leukemia, especially B cell acute lymphoblastic leukemia (B-ALL), the HSA21 genes contribute malignancies remain largely undefined. Here, we report overexpressed required for B-ALL. Genetic pharmacologic inhibition decreased leukemic...
Abstract An unwritten rule to resolve GNSS ambiguities in precise point positioning (PPP-AR) is that users should follow faithfully the frequency choices and observable combinations mandated by satellite clock phase bias providers. Switching other frequencies of measurements requires clocks be converted, albeit a roundabout way, agree with new code biases. Satellite biases, on hand, are prescribed conventionally as wide-lane narrow-lane combinations, which prevents from resolving case...
Abstract Camellia oil extracted from seeds is rich in unsaturated fatty acids and secondary metabolites beneficial to human health. However, no oil-tea tree genome has yet been published, which a major obstacle investigating the heredity improvement of trees. Here, using both Illumina PicBio sequencing technologies, we present first chromosome-level sequence species chekiangoleosa Hu. (CCH). The assembled consists 15 pseudochromosomes with size 2.73 Gb scaffold N50 185.30 Mb. At least 2.16...
Acute megakaryoblastic leukemia (AMKL) is a heterogeneous disease generally associated with poor prognosis. Gene expression profiles indicate the existence of distinct molecular subgroups, and several genetic alterations have been characterized in past years, including t(1;22)(p13;q13) trisomy 21 GATA1 mutations. However, majority patients do not present known mutations, limited access to primary patient leukemic cells impedes efficient development novel therapeutic strategies. In this...
Primary myelofibrosis (PMF) is a clonal hematologic malignancy characterized by BM fibrosis, extramedullary hematopoiesis, circulating CD34+ cells, splenomegaly, and propensity to evolve acute myeloid leukemia. Moreover, the spleen of patients harbor atypical, clustered megakaryocytes, which contribute disease secreting profibrotic cytokines. Here, we have revealed that megakaryocytes in PMF show impaired maturation associated with reduced GATA1 protein. In investigating cause...
Abstract Prediction of the height a water-flowing fracture zone (WFFZ) is foundation for evaluating water bursting conditions on roof coal. By taking Binchang mining area as study and conducting an in-depth influence coal seam thickness, burial depth, working face length, category WFFZ, we proposed that proportion hard rock in different ranges should be used to characterise WFFZ height. Based data its index obtained from field observations, prediction model established using combination...
Abstract Background Recently, many studies have been conducted to examine immune response modification at epigenetic level, but the candidate effect of RNA 5‐methylcytosine (m 5 C) on tumor microenvironment (TME) acute myeloid leukemia (AML) is still unknown present. Methods We assessed patterns m C among 417 AML cases by using nine regulators. Thereafter, we associated those identified with TME cell infiltration features. Additionally, stepwise regression and LASSO Cox analyses were for...
MADS-box genes encode transcription factors that affect plant growth and development. Camellia chekiangoleosa is an oil tree species with ornamental value, but there have been few molecular biological studies on the developmental regulation of this species. To explore their possible role in C. lay a foundation for subsequent research, 89 were identified across whole genome first time. These present all chromosomes found to expanded by tandem duplication fragment duplication. Based results...
Abstract Polyploids are common in Camellia sect. Paracamellia , which contain many important oil crop species. However, their complex evolutionary history is largely unclear. In this study, 22 transcriptomes and 19 plastomes of related species were sequenced assembled, providing the most completed taxa sampling Oleifera C . Phylogenetic trees reconstructed with predicted single‐copy nuclear genes plastomes. demonstrated that should be merged into Cytonuclear discordance network analyses...
The WRKY gene family is essential for controlling a variety of plant physiological functions, yet the involvement specific members in pigment biosynthesis and accumulation Camellia chekiangoleosa remains unexplored, particularly anthocyanins carotenoids, which play crucial roles pigmentation C. chekiangoleosa. This study systematically identified 87 genes across 15 chromosomes through bioinformatic approaches. Further structural phylogenetic analyses these TFs enabled their classification...
We used large samples of expressed sequence tags to characterize the patterns codon usage bias (CUB) in seven different Citrus species and analyze their evolutionary effect on selection base composition. found that A- T-ending codons are predominant species. Next, we identified 21 for 18 amino acids were considered preferred all then performed correspondence analysis constructed plots effective number (ENCs) synonymous usage. Multiple regression showed gene expression each had a constant...
Quercus variabilis is a tree species of ecological and economic value that widely distributed in China. To effectively evaluate, use, conserve resources, we applied 25 pairs simple sequence repeat (SSR) primers to study its genetic diversity structure 19 natural forest or secondary populations Q. (a total 879 samples). A 277 alleles were detected. Overall, the average expected heterozygosity (He) was 0.707 allelic richness (AR) 7.79. manifested loss heterozygosity, mean inbreeding...