A5020526656- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Hematological disorders and diagnostics
- Virology and Viral Diseases
- Viral Infections and Vectors
- Salmonella and Campylobacter epidemiology
- Amoebic Infections and Treatments
- Mosquito-borne diseases and control
- COVID-19 and healthcare impacts
- Antibiotic Resistance in Bacteria
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- Viral Infections and Outbreaks Research
- Immune responses and vaccinations
- Gout, Hyperuricemia, Uric Acid
- Biosensors and Analytical Detection
- Parasite Biology and Host Interactions
- Malaria Research and Control
- Inflammasome and immune disorders
- Liver Disease and Transplantation
- Syphilis Diagnosis and Treatment
- Phagocytosis and Immune Regulation
- Respiratory viral infections research
- Vibrio bacteria research studies
- Travel-related health issues
Japanese Red Cross Narita Hospital
2018-2025
A 35-year-old woman presented with fever and mild diarrhoea without any respiratory symptoms 9 days after travelling to Japan from Wuhan, China. Her computed tomography scan revealed pneumonia. The first polymerase chain reaction (PCR) test on throat swab for the novel corona virus upon admission was negative. Therefore, she treated community-acquired pneumonia, but persisted. On hospital day 5, PCR induced sputum positive, a second remained She discharged, fully recovered, 12. lower tract...
The mortality of coronavirus disease 2019 (COVID-19) is strongly correlated with pulmonary vascular pathology accompanied by severe acute respiratory syndrome 2 (SARS-CoV-2) infection–triggered immune dysregulation and aberrant activation platelets. We combined histological analyses using field emission scanning electron microscopy energy-dispersive X-ray spectroscopy the lungs from autopsy samples single-cell RNA sequencing peripheral blood mononuclear cells to investigate pathogenesis...
Abstract Purpose Auto-antibodies (auto-abs) to type I interferons (IFNs) have been identified in patients with life-threatening coronavirus disease 2019 (COVID-19), suggesting that the presence of auto-abs may be a risk factor for severity. We therefore investigated mechanism underlying COVID-19 exacerbation induced by IFNs. Methods evaluated plasma from 123 measure performed single-cell RNA sequencing (scRNA-seq) peripheral blood mononuclear cells and conducted epitope mapping auto-abs....
Carbapenem-resistant Gram-negative bacilli (CRGNB), especially Enterobacterales, Pseudomonas aeruginosa and Acinetobacter baumannii, are critical pathogens associated with excess morbidity mortality. To elucidate their molecular epidemiology clinical outcomes in Japan, patients CRGNB were enrolled the MDR organisms research network (MDRnet) consisting of eight tertiary care facilities. Between 2019 2022, 246 unique carbapenem-resistant Enterobacterales (CRE), P. (CRPA) A. baumannii (CRAB)...
A 42-year-old man exhibiting hypoxia was diagnosed with coronavirus disease 2019. He had medical histories of type 2 diabetes, hyperlipidemia, hyperuricemia, and gout attack. received favipiravir for compassionate use 14 days. Subsequently, he showed increased uric acid levels developed acute gouty arthritis. Favipiravir may induce not only hyperuricemia but also It should therefore be used caution in patients a history those especially when at higher dose longer duration than is typical.
We herein report the first case of a fever induced by favipiravir, potential coronavirus disease 2019 therapeutic drug. An 82-year-old man diagnosed with bilateral pneumonia was transferred to our hospital following positive severe acute respiratory syndrome 2 polymerase chain reaction test. He treated compassionate use favipiravir. Both his oxygen demand and gradually improved after admission; however, relapsed, C-reactive protein (CRP) levels increased on day 7. as being...
A 33-year-old hospitalized patient felt itching around his anus. Tiny white thread-like worms were observed perinatal region. Microscopic examination revealed the presence of elongated, one-sided, flattened eggs inside worm.
The Japanese Government has implemented quarantine measures in response to the COVID-19 pandemic. Individuals testing positive at airport's office were lodged either a designated hotel or hospital under Quarantine Act. aim of this study is describe management patients with admitted Act and evaluate its impact on medical resources. Data retrospectively collected, including demographics, comorbidities, status admission, clinical condition, treatment, outcomes, discharge, duration...
The quantitative antigen test based on the chemiluminescent enzyme immunoassay for SARS-CoV-2 has been used in international airports quarantine Japan. While cases of false-positive rapid tests were reported, with clinical information are rare. Here, we report a case acute respiratory infection whose was suspected to be false positive. A 9-month-old boy who presented fever and rhinorrhea admitted our hospital under Quarantine Act. He diagnosed COVID-19 performed at station. None accompanying...
Campylobacter fetus has rarely been reported as a pathogen of spontaneous bacterial peritonitis (SBP). A 60-year-old man with cirrhosis and diabetic nephropathy developed diarrhea, abdominal pain, fever. Abdominal paracentesis revealed significantly increased neutrophil count in the ascites. He was diagnosed having SBP treated empirically ceftriaxone. Five days later, blood culture performed on day admission yielded spiral-shaped gram negative bacilli. Both ascites stool cultures were...
Japan has maintained measles elimination status since 2015. However, sporadic outbreaks of have been continuously reported. Here, we report a case measles-infected postpartum mother and infant in Japan. A 28-year-old Japanese woman, who had previously received dose the vaccination, experienced fever 5 days postpartum. Subsequently, maculopapular rash appeared, she was diagnosed with measles. Moreover, her baby developed on 13th day life, 2 after postexposure prophylaxis intravenous...