A5037240320- Probiotics and Fermented Foods
- Gut microbiota and health
- Infant Nutrition and Health
- Infant Health and Development
- Diet and metabolism studies
- Digestive system and related health
- Fatty Acid Research and Health
- Pediatric health and respiratory diseases
- Microbial Metabolites in Food Biotechnology
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Diet, Metabolism, and Disease
- Eicosanoids and Hypertension Pharmacology
- Inflammatory Bowel Disease
- Antioxidant Activity and Oxidative Stress
- Protein Hydrolysis and Bioactive Peptides
- Cholesterol and Lipid Metabolism
- Immune Response and Inflammation
- SARS-CoV-2 and COVID-19 Research
- Ovarian function and disorders
- Food Allergy and Anaphylaxis Research
- Nanoparticle-Based Drug Delivery
- Liver Disease Diagnosis and Treatment
- Health and Lifestyle Studies
- Genomics and Phylogenetic Studies
Kerry Group (Ireland)
2025
Biosearch Life (Spain)
2014-2023
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2017
Biosearch Technologies (United States)
2015
Universidad de Alcalá
2014
Newbiotechnic (Spain)
2006-2009
The cardiovascular effects of probiotics Lactobacillus fermentum CECT5716 (LC40), or L. coryniformis CECT5711 (K8) plus gasseri CECT5714 (LC9) (1:1) in spontaneously hypertensive rats (SHR) were evaluated.Ten Wistar Kyoto (WKY) and 30 SHR randomly assigned to four groups (n = 10): a control WKY group, groups, an group treated with LC40, K8/LC9 for 5 weeks (at dose 3.3 × 10(10) colony-forming units/day drinking water). Long-term administration reduced systolic blood pressure. consumption...
Breast milk is an important factor in the initiation, development, and composition of neonatal gut microbiota. In a previous study, authors isolated lactic acid bacteria from healthy mothers. Since some identified isolates belonged to genus Lactobacillus, objective this work was evaluate probiotic potential 2 Lactobacillus gasseri 1 fermentum strains. Different assays, including survival conditions simulating those existing gastrointestinal tract, production antimicrobial compounds,...
ABSTRACT Objectives: The aim of the study was to examine effects a follow‐on formula containing Lactobacillus fermentum CECT5716 ( L ) on incidence infections in infants between ages 6 and 12 months. Patients Methods: A randomized double‐blinded controlled including at age months conducted. Infants were assigned randomly either supplemented with plus galactooligosaccharide (experimental group, EG), or same only (control CG). main outcome for 6‐month duration study. Results: EG showed...
The antimicrobial potential of four lactobacilli (Lactobacillus salivarius CECT5713, Lactobacillus gasseri CECT5714, L. CECT5715 and fermentum CECT5716), isolated from fresh human breast milk, was evaluated in this study compared with coryniformis CECT5711, a reuterin-producing strain an artisan goat's cheese.Agar diffusion tests, competitive adhesion assays mucin expression were carried out order to value the antibacterial properties strains. capability strains tested vivo by using murine...
In this study, 20 women with staphylococcal mastitis were randomly divided in two groups. Those the probiotic group daily ingested 10 log(10) CFU of Lactobacillus salivarius CECT5713 and same quantity gasseri CECT5714 for 4 weeks, while those control one only excipient. Both lactobacillus strains originally isolated from breast milk. On day 0, mean counts groups similar (4.74 4.81 CFU/ml, respectively), but lactobacilli could not be detected. 30, count (2.96 CFU/ml) was lower than that (4.79...
The ability of two different Lactobacillus strains (Lactobacillus salivarius CECT5713 and fermentum CECT5716), isolated from human breast milk, to modulate the immune response was examined.In rodent bone-marrow-derived macrophages (BMDM), presence Lact. CECT5716 induced pro-inflammatory cytokines, in contrast activation IL-10 by CECT5713. Although both reduced lipopolysaccharide (LPS)-induced inflammatory BMDM, effect more efficient, probably because production higher amounts cytokine. In...
To compare the intestinal anti-inflammatory effects of two probiotics Lactobacillus fermentum and salivarius in mouse colitis, focusing on their impact selected miRNAs microbiota composition.Male C57BL/6J mice were randomly assigned to four groups (n = 10): non-colitic, DSS colitic treated with (5 × 108 CFU/mouse/day). Both ameliorated macroscopic colonic damage. They improved expression markers involved immune response, miR-155 miR-223. L. also restored miR-150 miR-143 expression, linked...
The intestinal anti-inflammatory effects of two probiotics isolated from breast milk, Lactobacillus reuteri and L. fermentum, were evaluated compared in the trinitrobenzenesulfonic acid (TNBS) model rat colitis. Colitis was induced rats by intracolonic administration 10 mg TNBS dissolved 50% ethanol (0.25 ml). Either or fermentum daily administered orally (5 x 10(8) colony-forming units suspended 0.5 ml skimmed milk) to each group (n 10) for 3 weeks, starting 2 weeks before colitis...
Obesity is associated with intestine dysbiosis and characterized by a low-grade inflammatory status, which affects vascular function. In the present study, we evaluated effects of probiotic immunomodulatory properties, Lactobacillus coryniformis CECT5711, in obese mice fed on an HFD (high-fat diet). The treatment was given for 12 weeks, it did not affect weight evolution, although reduced basal glycaemia insulin resistance. L. administration to HFD-induced induced marked changes microbiota...
The aim is to analyze whether the probiotic Lactobacillus fermentum CECT5716 (LC40) can prevent endothelial dysfunction and hypertension induced by tacrolimus in mice.Tacrolimus increases systolic blood pressure (SBP) impairs endothelium-dependent relaxation acetylcholine these effects are partially prevented LC40. Endothelial related both increased nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX2) uncoupled nitric oxide synthase (eNOS)-driven superoxide production...
Previous studies have reported that probiotics may improve clinical and inflammatory parameters in patients with obesity metabolic syndrome (MetS). Lactobacillus (L.) reuteri V3401 has shown promising results on the components of MetS animal studies. We aimed to evaluate effects L. together healthy lifestyle recommendations adult MetS.We carried out a randomized, crossover, placebo-controlled, single-center trial which we included 53 newly diagnosed MetS. Patients were block randomly...
To investigate the intestinal anti-inflammatory effect and mechanism of a probiotic Lactobacillus salivarius ssp. CECT5713 in TNBS model rat colitis.Female Wistar rats (180-200 g) were used this study. A group administered orally L. (5x10(8) CFU suspended 0.5 mL skimmed milk) daily for 3 wk. Two additional groups reference, non-colitic control colitic without treatment, which received vehicle to administer probiotic. weeks after starting experiment, rendered by intracolonic administration 10...