- Maternal and Perinatal Health Interventions
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Maternal and fetal healthcare
- Airway Management and Intubation Techniques
- Anesthesia and Sedative Agents
- Cardiovascular Issues in Pregnancy
- Maternal Mental Health During Pregnancy and Postpartum
- Respiratory Support and Mechanisms
- Emergency and Acute Care Studies
- Healthcare Policy and Management
- Hemodynamic Monitoring and Therapy
- Pediatric Pain Management Techniques
- Anesthesia and Neurotoxicity Research
- Global Maternal and Child Health
- Nausea and vomiting management
- Respiratory and Cough-Related Research
- Pregnancy-related medical research
- Cardiac Structural Anomalies and Repair
- Intensive Care Unit Cognitive Disorders
- Tracheal and airway disorders
- Connective tissue disorders research
- Electrolyte and hormonal disorders
- Sepsis Diagnosis and Treatment
- Pregnancy and Medication Impact
Columbia University
2016-2025
Columbia University Irving Medical Center
2021-2024
Inserm
2003-2020
Agency for Healthcare Research and Quality
2019-2020
Assistance Publique – Hôpitaux de Paris
2007-2019
Hôpital Bichat-Claude-Bernard
2009-2019
Université Claude Bernard Lyon 1
2008-2019
Université Paris Cité
2011-2019
Infection, Anti-microbiens, Modélisation, Evolution
2019
Sorbonne Paris Cité
2013-2017
Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background Compared with neuraxial anesthesia, general anesthesia for cesarean delivery is associated increased risk of maternal adverse events. Reducing avoidable anesthetics may improve safety obstetric care. study examined events, trends, and factors potentially delivery. Methods retrospective analyzed cases without a recorded indication or contraindication to in York State hospitals, 2003...
Increased risks of cerebral venous thrombosis or subdural hematoma, bacterial meningitis, persistent headache, and low back pain are suggested in obstetric patients with postdural puncture headache (PDPH). Acute postpartum such as PDPH may also lead to depression. This study tested the hypothesis that is associated significantly increased major neurologic other maternal complications.This retrospective cohort consisted 1,003,803 women who received neuraxial anesthesia for childbirth New York...
OBJECTIVE: To analyze racial and ethnic disparities in failure to rescue (ie, death) associated with severe maternal morbidity describe temporal trends. METHODS: This was a retrospective cohort study using administrative data. Data for delivery hospitalizations morbidity, as defined by the Centers Disease Control Prevention, were abstracted from 1999–2017 National Inpatient Sample. Race ethnicity categorized into non-Hispanic White (reference), Black, Hispanic, other, missing. The outcome...
Addressing severe maternal morbidity (SMM) is a public health priority in the US. Use of labor neuraxial analgesia for vaginal delivery suggested to reduce risk postpartum hemorrhage (PPH), leading cause preventable morbidity.
We evaluated ultrasonic examination as a diagnostic tool for catheter misplacement and pneumothorax after central venous insertion. Physicians in the intensive care unit (ICU) performed examinations, results were compared with those of chest radiography. Eighty-five catheters (70 subclavian 15 internal jugular) inserted into 81 patients; 10 misplacements one occurred. Ultrasonic feasibility was 99.6%. The only all except diagnosed by ultrasound. Taking consideration research, did not give...
The aims of this study were, first, to identify risk factors for microbiology-proven postoperative pneumonia after cardiac surgery and, second, develop and validate a preoperative scoring system the pneumonia. A single-center cohort study. All consecutive patients undergoing between January 2006 July 2011. None. Multivariate analysis was performed on data from operated December 2008 (training set). External temporal validation 2009 2011 (validation Preoperative variables identified in...
To assess the association between structural racism and labor neuraxial analgesia use.
Identification of risk factors for adverse obstetrical outcomes after appendectomy and cholecystectomy during pregnancy is necessary evidence-based reduction adequate patient counseling.
De-escalation is strongly recommended for antibiotic stewardship. No studies have addressed this issue in the context of health care-associated intra-abdominal infections (HCIAI). We analyzed factors that could interfere with process and their clinical consequences intensive care unit (ICU) patients HCIAI.All consecutive admitted management HCIAI who survived more than 3 days following diagnosis, remained ICU days, did not undergo early reoperation during first were prospectively an...
Individual assessment of the amplitude a physiologic reflex evoked by standardized noxious test (SNT) before surgical stimulation has been suggested to predict movement upon forthcoming stimulation. This study aimed compare ability pupillary dilatation (PDRA) an SNT and estimated remifentanil effect-site concentration (Ce) stimulation.Eighty female patients were anesthetized for vacuum aspiration with propofol (Ce 4 μg/ml) remifentanil. Remifentanil Ce was randomized 0, 1, 3, or 5 ng/ml....
Persistent peritonitis is a frequent complication of secondary requiring additional reoperations and antibiotic therapy. This situation raises specific concerns due to microbiological changes in peritoneal samples, especially the emergence multidrug-resistant (MDR) strains. Although this has been extensively studied, rate dynamics MDR strains have rarely analysed.We compared clinical, therapeutic data consecutive ICU patients admitted for postoperative either without subsequent reoperation...
BACKGROUND: Previous research suggests that, compared with regional anesthesia, general anesthesia is associated increased odds of postoperative depressive disorders. No study has specifically evaluated the possible protective effect neuraxial for cesarean delivery on maternal mental health anesthesia. This exploratory was designed to test hypothesis that severe postpartum depression (PPD) requiring hospitalization METHODS: retrospective cohort included cases performed in New York State...
Racial and ethnic concordance between patients health care providers increases patient satisfaction but has not been examined in obstetric anesthesia care. This study evaluated the association racial with management of pain during cesarean delivery (PDCD).
Abstract Background Cesarean delivery (CD) is associated with significantly increased risks of anesthesia-related adverse events (ARAEs) and nonanesthetic perioperative morbidity compared vaginal delivery. Temporal trends in these outcomes remain unknown despite efforts to improve maternal safety. This study examines temporal ARAEs complications CDs New York hospitals. Methods Data are from the State Inpatient Database for York, 2003–2012. ARAEs, including minor major were identified through...
BACKGROUND: Compared to neuraxial anesthesia, general anesthesia (GA) for cesarean delivery is associated with an increased risk of postpartum depression (PPD) requiring hospitalization. However, obstetric complications occurring during childbirth (eg, stillbirth) are both use GA and PPD, may account the reported association between PPD. This study assessed PPD hospitalization, outpatient visit, or emergency department (ED) accounting complications. METHODS: retrospective cohort included...
Conflicting results have been reported on the effect of anxiety propofol dose required for inducing loss consciousness (LOC). The hemodynamic effects anxiety, increased heart rate (HR), and cardiac output may account these discrepancies. We therefore designed this study to address, first, perioperative HR LOC and, second, HR.Forty-five ASA physical status I-II female patients undergoing gynecological surgery were studied. Anxiety was assessed in operating room with State-Trait Inventory...
In Brief BACKGROUND: Pain intensity is usually self-rated by patients with a numeric rating scale (NRS) but this cannot be used for noncommunicating patients. anesthetized patients, experimental noxious stimulus increases pupillary diameter (PD) and light reflex amplitude (PLRA), the difference between PD before after stimulation. Labor pain an intense acute nonexperimental stimulus, effectively relieved epidural analgesia. prospective observational study, we therefore describe effects of...
Patients assess their own pain with a numerical rating scale (NRS). In the postanaesthesia care unit (PACU), NRS helps to determine and monitor analgesic administration, but is useless in patients who are unable communicate. non-PACU patients, acute increases pupillary diameter light reflex amplitude (PLRA), difference between before after stimulation.To study association postoperative (NRS) or PLRA PACU routine anaesthetic care.Cross-sectional cohort study.Bichat-Claude Bernard Hospital,...
BACKGROUND: Medicaid expansions under the Affordable Care Act have increased insurance coverage and prenatal care utilization in low-income women. However, it is not clear whether they are associated with any measurable improvement maternal health outcomes. In this study, we compared changes incidence of severe morbidity (SMM) during delivery hospitalizations between low- high-income women 2014 expansion New York State. METHODS: Data for retrospective cohort study came from 2006–2016 State...