A5062178877- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Catalytic C–H Functionalization Methods
- Catalytic Cross-Coupling Reactions
- Metal-Organic Frameworks: Synthesis and Applications
- Sulfur-Based Synthesis Techniques
- Synthesis and Catalytic Reactions
- Radical Photochemical Reactions
- Crystallography and molecular interactions
- Magnetism in coordination complexes
- Asymmetric Hydrogenation and Catalysis
- Cyclopropane Reaction Mechanisms
- Covalent Organic Framework Applications
- Catalytic Alkyne Reactions
- Metal complexes synthesis and properties
- Crystal structures of chemical compounds
- Oxidative Organic Chemistry Reactions
- Carbon dioxide utilization in catalysis
- Lanthanide and Transition Metal Complexes
- Advanced Photocatalysis Techniques
- Molecular Sensors and Ion Detection
- Electrochemical Analysis and Applications
- Advanced Nanomaterials in Catalysis
- Organoboron and organosilicon chemistry
- Dental materials and restorations
Collaborative Innovation Center of Advanced Microstructures
2016-2025
Nanjing University
2016-2025
Jinhua Polytechnic
2024
First People's Hospital of Nanning
2024
Qilu University of Technology
2021-2023
Shandong Academy of Sciences
2021-2023
Weihai Chest Hospital
2021
Oregon State University
2014-2021
Institute of Chemistry
2016-2020
Scripps Research Institute
2010-2020
A novel Pd(II)-catalyzed ortho-C−H olefination protocol has been developed using spatially remote, unprotected tertiary, secondary, and primary alcohols as the directing groups. Mono-N-protected amino acid ligands were found to promote reaction, an array of olefin coupling partners could be used. When electron-deficient alkenes used, resulting olefinated intermediates underwent subsequent oxidative intramolecular cyclization give corresponding pyran products, which converted into...
Cd(<sc>ii</sc>) frameworks with amino functionalized sites show high sensitivity for the detection of Fe(<sc>iii</sc>) and antibiotics such as nitrofurazone.
A Pd(II)-catalyzed C-H activation/C-O cyclization reaction directed by a proximate hydroxyl group has been developed. This provides new method for constructing dihydrobenzofurans, including spirocyclic analogues, process that is potentially applicable to natural product synthesis.
This review focuses on the recent development of luminescent MOFs with synthetic approaches and their application in sensing biomolecules.
A Pd(II)-catalyzed C–H carbonylation protocol of phenethyl alcohols has been developed using amino acid ligands to promote the reaction. This transformation provides an expedient route 1-isochromanone motifs, which are common structural elements in natural products and other biologically active compounds. concise synthesis a histamine release inhibitor showcases utility this transformation.
A range of Rh(III)-catalyzed ortho-C-H functionalizations have been developed; however, extension this reactivity to remote C-H through large-ring rhodacyclic intermediates has yet be demonstrated. Herein we report the first example use a U-shaped nitrile template direct meta-C-H activation via postulated 12-membered macrocyclic intermediate. Because ligands used for Rh(III) catalysts are significantly different from those Pd(II) catalysts, offers new opportunities future development...
Five new metal complexes, [Zn3(L1)2(BTC)2]·6H2O (1), [Zn3(L1)(BTC)2] (2), [Cd3(L1)(BTC)2] (3), [Cd3(L2)(BTC)2]·4H2O (4), and [Cd3(L2)(BTC)2(H2O)2] (5), have been successfully synthesized by solvothermal reactions of corresponding salts with 1,3,5-benzenetricarboxylic acid (H3BTC) imidazole-containing ligands 1,3,5-tris(imidazol-1-ylmethyl)benzene (L1) 3,3′,5,5′-tetra(imidazol-1-yl)-1,1′-biphenyl (L2). The structures the complexes were determined single crystal X-ray diffraction analysis....
Rhodium(<sc>iii</sc>)-catalyzed C–H olefination reaction using air as the sole oxidant.
Zinc(<sc>ii</sc>) MOFs show selective adsorption of CO<sub>2</sub> over N<sub>2</sub> and good selectivity for the detection acetone <italic>via</italic> fluorescence quenching.
Rh(III)-catalyzed meta-C–H functionalization reactions are still rare. Herein, we report the first example of alkenylation with disubstituted alkynes directed by a U-shaped nitrile template. Exclusive regio-selectivity has been achieved using unsymmetrical aryl and alkyl-disubstituted to afford synthetically valuable trisubstituted olefins. Propargyl alcohols also compatible, affording complex allylic alcohols. Notably, transition metal-catalyzed meta-alkenylation not successful Pd catalysts.
A combination of carbon dioxide (CO2) capture and chemical fixation in a one-step process is attractive for chemists environmentalists. In this work, by incorporating chelating multiamine sites to enhance the binding affinity toward CO2, two novel metal–organic frameworks (MOFs) [Zn2(L)(2,6-NDC)2(H2O)]·1.5DMF·2H2O (1) [Cd2(L)(2,6-NDC)2]·1.5DMF·2H2O (2) (L = N1-(4-(1H-1,2,4-triazole-1-yl)benzyl)-N1-(2-aminoethyl)ethane-1,2-diamine, 2,6-H2NDC 2,6-naphthalenedicarboxylic acid, DMF...
Multidimensional supramolecular assemblies based on cucurbit[n]uril (n = 6 or 7) were constructed via the outer-surface interactions of cucurbit[n]urils with polyaromatic compound 4,4',4″-benzene-1,3,5-triyl-tribenzoate as a structure-directing agent. Most impressively, cucurbit[6]uril-based assembly exhibits high selectivity for capture cesium cations among common alkali metal ions in basic medium and releases under acidic conditions. This reversible process enables possible applications...
Abstract Ligand development for rhodium(III)‐catalyzed C−H activation reactions has largely been limited to cyclopentadienyl (Cp) based scaffolds. 2‐Methylquinoline now identified as a feasible ligand that can coordinate the metal center of Cp*RhCl accelerate cleavage bond N ‐pentafluorophenylbenzamides, providing new structural lead design. The compatibility this reaction with secondary free amines and anilines also overcomes limitations palladium(II)‐catalyzed amination reactions.
Abstract Ubiquitous tyrosinase catalyses the aerobic oxidation of phenols to catechols through binuclear copper centres. Here, inspired by Fischer indole synthesis, we report an iridium-catalysed tyrosinase-like approach catechols, employing oxyacetamide-directed C–H hydroxylation on phenols. This method achieves one-step, redox-neutral synthesis with diverse substituent groups under mild conditions. Mechanistic studies confirm that directing group (DG) oxyacetamide acts as oxygen source....
A ligand-promoted RhIII -catalyzed C(sp2 )-H activation/thiolation of benzamides has been developed. Using bidentate mono-N-protected amino acid ligands led to the first example aryl thiolation reactions directed by weakly coordinating directing amide groups. The reaction tolerates a broad range amides and disulfide reagents.
Abstract Synthetic methods inspired by Nature often offer unique advantages including mild conditions and biocompatibility with aqueous media. Inspired an ergothioneine biosynthesis protein EgtB, a mononuclear non-haem iron enzyme capable of catalysing the C–S bond formation sulfoxidation, herein, we discovered metal-free C–H sulfenylation/intramolecular rearrangement cascade reaction employing internally oxidizing O–N as directing group. Our strategy accommodates variety oxyamines good site...
Abstract Carbon dioxide (CO 2 ) capture and transformation are important for decreasing the concentration of atmospheric CO . To effectively further fix it into valuable chemical products, functionalized dynamic metal–organic frameworks (MOFs) have been utilized not only because their inherent cavity accommodating but also owing to reversible structural transformations in response external stimuli regulating reaction. Herein, we report a functional MOF [Cd 3 (L) (BDC) ] ⋅ 16 DMF ( MOF‐1 ;...
Six new coordination polymers [Zn(L)0.5(CO3)]·H2O (1), [Zn(L)0.5(DC)]·H2O (2), [Cd(L)0.5(DC)] (3), [Cd(L)0.5(PBEA)]·H2O (4), [Cd2(L)(MBEA)2]·4H2O (5), and [Zn(L)0.5(MBEA)]·2H2O (6) with different structures topologies were successfully synthesized by hydrothermal reactions of zinc(II)/cadmium(II) salts rigid ligand 3,3′,5,5′-tetra(1H-imidazol-1-yl)-1,1′-biphenyl (L) auxiliary multicarboxylic acids 1,3,5-tri(4-carboxyphenyl)benzene (H3BTB), 1,4-benzenediacrylic acid (H2DC),...
2,6-Bis-arylated phenols are rarely reported and synthetically challenging. We report that switching between internal external oxidation could be a general strategy to realize these bis-functionalized products.