Hanqing Li

ORCID: 0000-0002-8837-532X
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About
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Research Areas
  • Photonic and Optical Devices
  • Advanced Sensor and Energy Harvesting Materials
  • Advanced MEMS and NEMS Technologies
  • Adhesion, Friction, and Surface Interactions
  • Innovative Energy Harvesting Technologies
  • Optical Network Technologies
  • Conducting polymers and applications
  • Advanced MIMO Systems Optimization
  • Electrohydrodynamics and Fluid Dynamics
  • Supercapacitor Materials and Fabrication
  • Microfluidic and Capillary Electrophoresis Applications
  • Force Microscopy Techniques and Applications
  • Plant-based Medicinal Research
  • Cooperative Communication and Network Coding
  • Multimodal Machine Learning Applications
  • HER2/EGFR in Cancer Research
  • Pharmacological Effects of Natural Compounds
  • Advanced Photonic Communication Systems
  • Cognitive Radio Networks and Spectrum Sensing
  • Photonic Crystals and Applications
  • Metabolism, Diabetes, and Cancer
  • Thermochemical Biomass Conversion Processes
  • Drug Transport and Resistance Mechanisms
  • Orbital Angular Momentum in Optics
  • Domain Adaptation and Few-Shot Learning

Kunming University of Science and Technology
2024-2025

Shandong Agricultural University
2020-2025

Beijing University of Chemical Technology
2023-2025

Materials Science & Engineering
2025

Faculty (United Kingdom)
2025

Shanxi University
2016-2024

Dongfeng Motor (China)
2024

Inner Mongolia International Mongolian Hospital
2014-2024

National University of Defense Technology
2023-2024

Marine Design & Research Institute of China
2024

This paper presents photonic devices with 3 dB/cm waveguide loss fabricated in an existing commercial electronic 45 nm SOI-CMOS foundry process. By utilizing front-end fabrication processes the are monolithically integrated electronics same physical device layer as transistors achieving 4 ps logic stage delay, without degradation transistor performance. We demonstrate 8-channel optical microring-resonator filter bank and modulators, both controlled by digital circuits. developing a design...

10.1364/oe.20.012222 article EN cc-by Optics Express 2012-05-15

Resistance to 5-Fluorouracil (5-Fu) chemotherapy is the main cause of treatment failure in cure colon cancer. Therefore, there an urgent need explore a safe and effective multidrug resistance reversal agent for colorectal cancer, which would be great significance improving clinical efficacy. The dietary flavonoid kaempferol plays key role progression cancer 5-Fu resistance. However, molecular mechanism reversing human cells still unclear. We found that could reverse drug HCT8-R 5-Fu,...

10.3390/ijms23073544 article EN International Journal of Molecular Sciences 2022-03-24

We present a new monolithic silicon photonics technology suited for integration with standard bulk CMOS processes, which reduces costs and improves opto-electrical coupling compared to previous approaches. Our supports dense wavelength-division multiplexing dozens of wavelengths per waveguide. Simulation experimental results reveal an order magnitude better energy-efficiency than electrical links in the same generation. Exploiting key features our technology, we have developed...

10.1109/hoti.2008.11 article EN 2008-01-01

Silicon photonics is a promising technology for addressing memory bandwidth limitations in future many-core processors. This article first introduces new monolithic silicon-photonic technology, which uses standard bulk CMOS process to reduce costs and improve energy efficiency, then explores the logical physical implications of leveraging this processor-to-memory networks.

10.1109/mm.2009.60 article EN IEEE Micro 2009-07-01

We demonstrate a monolithic photonic integration platform that leverages the existing state-of-the-art CMOS foundry infrastructure.In our approach, proven XeF 2 post-processing technology and compliance with electronic process flows eliminate need for specialized substrates or wafer bonding.This approach enables intimate of large numbers nanophotonic devices alongside high-density, highperformance transistors at low initial incremental cost.We this by presenting grating-coupled,...

10.1364/oe.19.002335 article EN cc-by Optics Express 2011-01-24

Colon cancer is an aggressive malignancy with very limited therapeutic approaches. The available agents for colon show strong adverse effects and poor effectiveness, indicating the urgent need to identify new drugs this malignancy. Kaempferol, a flavonoid found in variety of natural foods, exhibits significant inhibitory on cancer. Here, it was that kaempferol inhibited proliferation human cells HCT116 DLD1 dose-dependent manner, IC50 values were 63.0 ± 12.9 98.3 15.9 μM, respectively. Also,...

10.1021/acs.jafc.0c07640 article EN Journal of Agricultural and Food Chemistry 2021-03-05

Cross domain object detection is a realistic and challenging task in the wild. It suffers from performance degradation due to large shift of data distributions lack instance-level annotations target domain. Existing approaches mainly focus on either these two difficulties, even though they are closely coupled cross detection. To solve this problem, we propose novel Target-perceived Dual-branch Distillation (TDD) framework. By integrating branches both source domains unified teacher-student...

10.1109/cvpr52688.2022.00935 article EN 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) 2022-06-01

Abstract Wound healing and infection remain significant challenges due to the ineffectiveness against multidrug‐resistant (MDR) bacteria complex oxidative wound microenvironments. To address these issues, thymoquinone‐reinforced injectable thermosensitive TQ@PEG‐PAF‐Cur hydrogels with dual functions of microenvironment reshaping photodynamic therapy are developed. The hydrogel comprises natural compound thymoquinone (TQ) poly (ethylene glycol)‐block‐poly (alanine‐co‐phenyl alanine)...

10.1002/adhm.202400049 article EN Advanced Healthcare Materials 2024-02-28

A piezoelectrically driven hydraulic amplification microvalve for use in compact high-performance pumping systems was designed, fabricated, and experimentally characterized. High-frequency, high-force actuation capabilities were enabled through the incorporation of bulk piezoelectric material elements beneath a micromachined annular tethered-piston structure. Large valve stroke at microscale achieved with an mechanism that amplified (40×-50×) limited into significantly larger motion membrane...

10.1109/jmems.2002.807471 article EN Journal of Microelectromechanical Systems 2003-02-01

// Jiangying Shi 1, * , Shuhua Shan Hanqing Li 2 Guisheng Song 3 and Zhuoyu 1,2 1 Institute of Biotechnology, Key Laboratory Chemical Biology Molecular Engineering National Ministry Education, Shanxi University, Taiyuan 030006, China College Life Science, Department Medicine, Division Gastroenterology, University Minnesota Medical School, Minneapolis, MN 55455, USA These authors have contributed equally to this work Correspondence to: Li, email: lzy@sxu.edu.cn Keywords: foxtail millet bran,...

10.18632/oncotarget.20216 article EN Oncotarget 2017-08-12

Colorectal cancer (CRC) is a common malignant tumor occurring in the colon. It has been known that gut microbiota complex ecosystem and plays an important role pathogenesis of colorectal cancer. Our previous study showed bound polyphenol inner shell (BPIS) from foxtail millet bran exhibited significant antitumor activities cells nude mice models. In present study, anticancer potential BPIS evaluated azoxymethane (AOM) dextran sodium sulfate (DSS)-induced mouse CRC model. Results could...

10.1021/acs.jafc.0c00370 article EN Journal of Agricultural and Food Chemistry 2020-02-26

A novel post-processing fabrication technique, based on XeF <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> etching, has been developed to locally remove the silicon substrate beneath polysilicon waveguides, enabling integration of low-loss strong-confinement microphotonics into standard bulk-silicon CMOS process flows.

10.1109/cleo.2008.4551466 article EN Conference on Lasers and Electro-Optics 2008-05-01

This study empirically investigates the influences of several parameters on surface morphology and etch rate in a high-aspect-ratio silicon etching process. Two function formulas were obtained, revealing relationship between controlled results. All experiments conducted an inductively coupled plasma system, using Bosch The tested trenches' width ranged from 15 to 1500 µm their depth 50 500 µm, which covers nearly all typical sizes micromechanical devices practical applications. are chamber...

10.1177/1687814017738152 article EN cc-by Advances in Mechanical Engineering 2017-12-01

Foxtail millet is the second-most widely planted species of and most important cereal food in China. Our previous study showed that bound polyphenol inner shell (BPIS) from foxtail bran displayed effective antitumor activities vitro vivo. The present research further implied BPIS has ability to reverse multidrug resistance colorectal cancer human HCT-8/Fu cells, IC50 values 5-fluorouracil (5-Fu), oxaliplatin (L–OHP), vincristine (VCR) were decreased form 6593 ± 53.8, 799 48.9, 247 10.3 μM...

10.1021/acs.jafc.8b01659 article EN Journal of Agricultural and Food Chemistry 2018-05-06

We demonstrate the first photonic chip designed in a commercial bulk CMOS process (65 nm node) using standard layers combined with scalable post-processing, enabling dense integration high-performance microprocessor electronics.

10.1109/cleo.2008.4551588 article EN Conference on Lasers and Electro-Optics 2008-05-01

We measure end-of-line polysilicon waveguide propagation losses of ~6-15 dB/cm across the telecommunication O-, E-, S-, C- and L-bands in a process representative high-volume product integration. The lowest loss 6.2 is measured at 1550 nm with 120 x 350 core geometry. reported characteristics are after thermal cycling full CMOS electronics that results 32% increase extracted material relative to as-crystallized samples. spectra fit an absorption model using defect state parameters identify...

10.1364/oe.20.007243 article EN cc-by Optics Express 2012-03-14

Abnormal glycerophospholipid (GPL) metabolism represented by phosphatidylcholine (PC) and phosphatidylethanolamine (PE) has been as a universal metabolic hallmark of cancer, which is involved in tumor progression. Our previous finding showed that peroxidase from foxtail millet bran (FMBP) exhibited significant anticolorectal cancer (CRC) activity vitro nude mice. Presently, the potential FMBP clinical application was further evaluated an azoxymethane (AOM)/dextran sodium sulfate...

10.1021/acs.jafc.0c03257 article EN Journal of Agricultural and Food Chemistry 2020-07-13
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