A5044658880- Diet, Metabolism, and Disease
- Cholesterol and Lipid Metabolism
- Diet and metabolism studies
- Nutritional Studies and Diet
- Genetic Associations and Epidemiology
- DNA Repair Mechanisms
- Biochemical Analysis and Sensing Techniques
- Food Security and Health in Diverse Populations
- Dietetics, Nutrition, and Education
- Nuclear Structure and Function
- Nutrition and Health in Aging
- Telomeres, Telomerase, and Senescence
- Obesity and Health Practices
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
Angiogenesis Foundation
2025
Tufts University
2020-2024
University of St. Thomas - Texas
2016
The Dietary Approaches to Stop Hypertension (DASH) diet score lowers blood pressure (BP). We examined interactions between genotype and the DASH in relation systolic BP. analyzed up 9 420 585 single nucleotide polymorphisms 127 282 individuals of 6 population groups (91% European population) from Cohorts for Heart Aging Research Genomic Epidemiology consortium (n=35 660) UK Biobank (n=91 622) performed population-specific cross-population meta-analyses. identified 3 loci European-specific...
12117 Background: Addressing nutritional issues in patients with cancer can reduce symptoms, shorten hospitalizations, enhance treatment adherence, and improve quality of life. However, most never receive nutrition counseling due to dietitian workforce shortages healthcare access disparities. Advances artificial intelligence (AI) high rates mobile device utilization among all demographics provide opportunities expand reach. This study assessed if guidance from an expert-designed AI platform,...
ChREBP (carbohydrate responsive element binding protein) is a transcription factor that responds to sugar consumption. Sugar-sweetened beverage (SSB) consumption and genetic variants in the CHREBP locus have separately been linked HDL-C (high-density lipoprotein cholesterol) triglyceride concentrations. We hypothesized SSB would modify association between dyslipidemia.Data from 11 cohorts Cohorts for Heart Aging Research Genomic Epidemiology consortium (N=63 599) UK Biobank (N=59 220) were...
Objectives: The physiological impact of dietary fiber (DF) consumption is difficult to ascertain given its wide range sources and properties. This review aims identify emerging candidate metabolite biomarkers capturing different DF intake. Methods: We searched four electronic databases (PubMed, Web Science, BIOSIS, CINAHL) using a combination keywords related (79), (9), intake biofluid (urine, blood, fecal). Search criteria included 2+ arm parallel studies, crossovers, observational studies....
We examined interactions between genotype and a Dietary Approaches to Stop Hypertension (DASH) diet score in relation systolic blood pressure (SBP).
Non‐homologous end‐joining (NHEJ) is the main repair pathway for processing double‐strand DNA breaks in Eukarya. In mammalian cells, NHEJ mediated by a complex of proteins comprised Ku subunits (Ku70 and Ku86), Ligase IV, XRCC4, Artemis, DNA‐PKcs XLF. Paradoxically, several these are also found at telomeres, despite fact that one functions structure telomeres to prevent from recognizing natural ends chromosomes as DSBs. For instance, present through interactions with resident telomeric like...
A meta-analysis of 11 CHARGE cohorts (N = 63,599) suggested that genetic variants within or near the CHREBP locus may modify associations between sugar sweetened beverage (SSB) consumption and high-density lipoprotein cholesterol (HDL-C) triglyceride (TG) concentrations. The study objective was to replicate these findings in a large independent cohort. Blood lipids 24-hour recalls were available for 57,794 adults European ancestry UK Biobank (2006-'10). SSBs included "squash" "fizzy" drinks...