A5070999349- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Immune Cell Function and Interaction
- MicroRNA in disease regulation
- Climate change and permafrost
- Electrocatalysts for Energy Conversion
- Chronic Lymphocytic Leukemia Research
- X-ray Diffraction in Crystallography
- CNS Lymphoma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Crystallization and Solubility Studies
- Advanced Battery Materials and Technologies
- Autoimmune and Inflammatory Disorders Research
- Cancer Immunotherapy and Biomarkers
- T-cell and Retrovirus Studies
- Advanced battery technologies research
- Neuroinflammation and Neurodegeneration Mechanisms
- Chalcogenide Semiconductor Thin Films
- Pain Mechanisms and Treatments
- Cryospheric studies and observations
- RNA modifications and cancer
- Immune cells in cancer
- Histiocytic Disorders and Treatments
Second Affiliated Hospital of Zhejiang University
2022-2025
Central South University
2025
Sichuan University
2015-2024
West China Hospital of Sichuan University
2017-2024
University of Science and Technology of China
2022-2024
Chinese Academy of Sciences
2021-2024
University of Hong Kong
2024
First Affiliated Hospital of Jinan University
2024
Zhejiang Sci-Tech University
2022-2024
Chinese University of Hong Kong
2024
The construction and understanding of synergy in well-defined dual-atom active sites is an available avenue to promote multistep tandem catalytic reactions. Herein, we construct a dual-hetero-atom catalyst that comprises adjacent Cu-N4 Se-C3 for efficient oxygen reduction reaction (ORR) activity. Operando X-ray absorption spectroscopy coupled with theoretical calculations provide in-depth insights into this mechanism ORR under realistic device operation conditions. heteroatom Se modulator...
Lead-free double perovskites have been considered as a potential environmentally friendly photovoltaic material for substituting the hybrid lead halide due to their high stability and nontoxicity. Here, lead-free perovskite Cs
<h3>Importance</h3> Married patients with cancer have better cancer-specific survival than unmarried patients. Increasing the early diagnosis and definitive treatment of among may reduce gap. <h3>Objectives</h3> To evaluate extent to which marriage is associated survival, stage at diagnosis, 9 common solid cancers recommend methods for reducing <h3>Design, Setting, Participants</h3> This retrospective, population-based cohort study included older 18 years who were diagnosed 1 between January...
The additive manufacturing of hardmetals has attracted great attention recently but faces significant challenges in low printing resolution and mechanical strength. Herein, the fabrication hardmetal parts with complex structures high surface quality by vat photopolymerization assisted a sintering process been achieved. This was enabled situ polymerization-induced microencapsulation WC powder, which simultaneously enhances photocuring ability sedimentation stability WC-Co slurry. powder is...
Background Glioblastoma (GBM), one of the most aggressive tumors brain, has no effective or sufficient therapies. Identifying robust biomarkers for response to immune checkpoint blockade (ICB) therapy, a promising treatment option GBM patients, is urgently needed. Methods We comprehensively evaluated lncRNA m 6 A modification patterns in A-sequencing (m A-seq) data tissues and systematically investigated stromal regulators these A-regulated lncRNAs. used single-sample gene-set enrichment...
Computational, thin-film deposition, and characterization approaches have been used to investigate the all-inorganic lead-free CsBi3I10 as a candidate act photovoltaic absorber. In this paper, was firstly predicted with layer crystal structure of stable hexagonal phase-like Cs3Bi2I9 then prepared by one-step coating also showing high purity phase crystallinity, very consistent theoretical calculation. After solvent annealing, absorption coefficient approximately 105 cm–1 in visible light...
Abstract Hypoxia is a critical factor in the malignant progression of glioma, especially for highly-invasive mesenchymal (MES) subtype. But detailed mechanisms hypoxia-induced glioma MES transition remain elusive. Pseudogenes, once considered to be non-functional relics evolution, are emerging as human tumorigenesis and progression. Here, we investigated clinical significance, biological function, protein disulfide isomerase family A member 3 pseudogene 1 (PDIA3P1) transition. In this study,...
Skull defect repair is a complex and critical medical challenge, there an urgent need to develop multifunctional tissue engineering scaffolds for skull regeneration. The success of bone depends on the construction that can regulate immune microenvironment regeneration mimic liquid crystal viscoelastic properties natural extracellular matrix. Hence, smart hydrogel (PEGDA5/AM15/CLC-BMP-4@MBG) with good biocompatibility ability modulate wound has been developed defects. consists chitin...
Abstract The malignant interaction between tumor cells and immune is one of the important reasons for rapid progression refractoriness glioblastoma (GBM). As an essential metabolic center M2 macrophages, inhibition protein kinase RNA‐like endoplasmic reticulum (PERK) leads to reduction macrophages. Nevertheless, restriction blood‐brain barrier (BBB) non‐specific cell targeting hinder application PERK inhibitors in GBM. Herein, optimal NP‐M‐M2pep developed successfully, which has shown...
Depth-to-bedrock (DTB) determines soil thickness in land surface models and controls the active depth of hydrological biogeochemical processes, particularly important permafrost regions where affects both hydrologic heat transfer. In this study, we evaluate sensitivity hydrothermal regime to DTB parameterization Community Land Model version 5.0 (CLM5.0) by comparing two datasets: DTB_P (default CLM5.0, developed Pelletier) DTB_SG (Shangguan-derived DTB) over three sites (BLH, TGL, XDT)...
Exhaustion of CD8+ tumor-infiltrating lymphocytes (TILs), characterized by the overexpression immune checkpoints (IC), is a major impediment to anti-tumor immunity. However, exhaustion status CD8+TILs in angioimmunoblastic T cell lymphoma (AITL) remains unclear. Therefore, we aimed elucidate AITL and its influence on prognosis.The correlation between IC expression was analyzed using single-cell RNA sequencing (n = 2), flow cytometry 20), 20). Biological changes related at different cytotoxic...
Rationale: Intracerebral hemorrhage (ICH) is a devastating cerebrovascular disease resulting from blood extravasating into the brain parenchyma.Escalation of erythrophagocytosis (a form efferocytosis), avoiding consequent release detrimental erythrocyte lysates, may be promising target ICH management.The ADAM17 inhibitor and liver X receptor (LXR) agonist could promote efficient efferocytosis injury repair.Nevertheless, poor bioavailability restriction blood-brain barrier (BBB) hinder their...
Magnetron sputtering has become an effective method in Sb2Se3 thin film photovoltaic. Research found that post-selenization treatments are essential to produce stoichiometric films with desired crystallinity and orientation for the sputtered Sb2Se3. However, influence of process on device performance rarely been explored. In this work, working pressure effect was thoroughly studied solar cells. High-quality obtained when a bilayer structure applied by at high (1.5 Pa) low (1.0 subsequently....
Abstract Background Programmed cell death protein-1 (PD-1) blockade therapies have demonstrated efficacy in nasopharyngeal carcinoma (NPC). Thyroid dysfunction is among the most common immune-related adverse events. This study aimed to explore clinical pattern of thyroid and its relationship with survival marker nonmetastatic NPC after immunotherapy. Methods From January 1, 2019, December 31, 2021, 165 pairs patients (165 without anti-PD-1 immunotherapy) matched by propensity score matching...