A5054296099- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Pancreatitis Pathology and Treatment
- Hepatitis C virus research
- Gallbladder and Bile Duct Disorders
- Appendicitis Diagnosis and Management
- Foreign Body Medical Cases
- Viral gastroenteritis research and epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Streptococcal Infections and Treatments
- Tracheal and airway disorders
- Pancreatic and Hepatic Oncology Research
- Amoebic Infections and Treatments
- Gut microbiota and health
- Congenital Anomalies and Fetal Surgery
- Eosinophilic Esophagitis
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Intestinal and Peritoneal Adhesions
Linkou Chang Gung Memorial Hospital
2025
State University of New York
2025
Columbia University Irving Medical Center
2025
SUNY Downstate Health Sciences University
2025
New York Stem Cell Foundation
2025
Chang Gung Memorial Hospital
2009-2023
American Institute of Ultrasound in Medicine
2023
Chang Gung University
2008-2019
Chang Gung Children's Hospital
2000-2018
Memorial Hospital of South Bend
1995-2014
A nationwide hepatitis B vaccination program was implemented in Taiwan July 1984. To assess the effect of on development hepatocellular carcinoma, we studied incidence this cancer children from 1981 to 1994.
We hypothesized that food sensitization (FS) in children could be linked to specific gut microbiota. The aim of our study is quantify and evaluate differences microbiota composition between with FS healthy controls.A case-control 23 22 was performed. Individual microbial diversity were analyzed via parallel barcoded 454 pyrosequencing targeting the 16S rRNA gene hypervariable V3-V5 regions.The exhibited lower both total (p = 0.01) bacterial phylum Bacteroidetes 0.02). In these children,...
Modulation of the cellular response by administration probiotic bacteria may be an effective strategy for preventing or inhibiting tumour growth. We orally pre-inoculated mice with probiotics Lactobacillus acidophilus NCFM (La) 14 d. Subcutaneous dorsal-flank tumours and segmental orthotopic colon cancers were implanted into using CT-26 murine adenocarcinoma cells. On day 28 after initiation, lamina propria colon, mesenteric lymph nodes (MLN) spleen harvested purified flow cytometry mRNA...
ABSTRACT Background: Calprotectin is a marker associated with intestinal inflammation. The aim of this study to explore the diagnostic value fecal calprotectin in predicting bacterial/viral diarrhea and application clinical course infectious diarrhea. Methods: Patients ages from 3 months 10 years were enrolled, each patient, 2 stool samples collected. Fecal levels determined by enzyme‐linked immunosorbent assay compared pathogen disease activity. A univariate linear regression was used...
Background: Acute diarrhea is a major cause of childhood morbidity and an economic burden for families. The aim this study to explore the effect probiotics on clinical symptoms, intestinal microbiota, inflammatory markers during diarrhea. Methods: Children (n = 81) aged six months years (mean age 2.31 years) hospitalized acute were randomized receive (Lactobacillus casei variety rhamnosus; n 42) or no 39) orally twice daily seven days. Feces samples also collected evaluate microbial content...
Abstract Purpose: In spite of the success hepatitis B immunization, still a significant proportion childhood hepatocellular carcinoma (HCC) failed to be prevented by immunization program. This study is aimed investigate problems in HCC prevention children. Experimental Design: All children ages 6 14 diagnosed between 1981 and 2000 Taiwan were collected from two national registry systems. We analyzed causes failure risk ratio among carriers born before versus after vaccination Results: The...
Background: Acute infectious diarrhea is a major cause of childhood morbidity and economic burden for families. We evaluate the clinical, microbiologic, immunologic effects probiotics in acute diarrhea. Methods: Children (n = 304) aged 3 months to 6 years hospitalized were randomized receive Bio-three (a mixture Bacillus mesentericus, Enterococcus faecalis, Clostridium butyricum) or placebo orally times daily 7 days. Fecal samples homogenized bacterial culture blood cells isolated cell...
This 3 year prospective study evaluated the sensitivity and specificity of abdominal ultrasonography color Doppler in 31 neonates with suspected malrotation or volvulus. Water instillation was used to detect duodenal dilatation, edema, malrotated bowels. Twenty patients ultrasonographic characteristics inversion superior mesenteric artery vein were later surgically proved have malrotation. Nine these 20 also had Sonographic features suggestive volvulus included dilation tapering...
To investigate the role of hepatitis B virus (HBV) infection in pediatric fulminant hepatic failure (FHF) after launch universal HBV vaccination, authors analyzed data from patients with FHF collected a nationwide collaborative study group. Children aged 1 month to 15 years who were diagnosed (62 males and 33 females) between 1985-1999 included. (hepatitis surface antigen [HBsAg] and/or immunoglobulin M core antibody [IgM anti-HBc] seropositive) accounted for 46% (43 95 cases) all cases FHF....
Although the detection of pediatric peptic ulcer disease (PUD) has recently been increasing, perforated (PPU) in children is rare. We report our experience with PPU children.The charts diagnosed at hospital from January 1986 to June 2005 were reviewed. Data obtained on demographics, coexisting clinical events, perforation sites, delay surgery, operative findings and methods, outcomes. The data analyzed using chi2, Student t test, multivariate logistic regression for possible risk...
There are no available data for outcomes in children's idiopathic superior mesenteric artery syndrome (SMAS) strictly treated conservatively. The aim of the study was to evaluate clinical and nutritional outcome children with SMAS.A 1-year prospective observation effects treatment performed 27 (8 boys, 19 girls) SMAS who underwent an upper gastrointestinal (UGI) series, ultrasound measurement aortomesenteric angle, treatment, assessment, growth evaluation, regular visits more than 12...
Necrotizing fasciitis is a rare but progressive soft tissue infection. This condition difficult to recognize in the early phase, when it often confused with cellulitis. We report cases of four children necrotizing fasciitis. The initial presentation these was Fever and swelling occurred within 24 h spreading erythema 4 12 h. Radiologic studies lesions showed thickening. Ultrasonography demonstrated distorted, thickened fascia fluid accumulation. Well-defined, loculated abscesses were two...
Adnexal torsion is an acute abdominal condition often confused with other diseases in children. The objective of this study to evaluate the diagnosis and characteristics adnexal children.We reviewed medical records all cases children whose was proven by surgery from 1992 2005. Neonatal were excluded.A total 49 included study, a mean age 12.5 years. Sixteen (32.6%) premenarchal girls, who more likely have missed at first clinical when compared postmenarchal girls (P = 0.032). Presenting...
Abstract Aim: To identify clinical, laboratory, and imaging characteristics associated with severe acute pancreatitis in children. Methods: This was a retrospective study of children under 18 years age between September 1993 August 2008. Severity graded according to established criteria. Clinical, laboratory radiological data for mild were collected analysis. Results: There 180 cases pancreatitis; 51 (28.3%) met criteria disease. Severe most commonly systemic disease (22 51; 43.1%) trauma...
Chronic granulomatous disease (CGD) is a rare genetic disorder that causes primary immunodeficiency. In addition to increasing infection susceptibility in various bodily systems, several ocular manifestations have been described males. This condition well males, due its X-linked recessive inheritance. However, here we present, our knowledge, the first cases of CGD chorioretinitis female carriers, possibly skewed X-inactivation (lyonization). Comprehensive multimodal imaging, including color...
Color Doppler ultrasonography was performed in 125 patients with 134 intussusceptions. flow present 121 cases of intussusception (group A) and absent 13 B). Young age duration symptoms greater than 48 hr were significantly related to the nonvisualization blood detected by color sonography (P < 0.05). The successful rate air reduction higher group A B (109 versus 4 13). is useful predict reducibility an intussuscepted intestine. this method not a contraindication for reduction.
We investigated the diameter of pancreatic duct using ultrasonography in 51 children with pancreatitis and age-matched healthy control over a 5 year period. The diameters body were measured simultaneously by sonography. mean ages acute chronic 9.7 +/- 3.9 10.3 3.1 years, respectively (range, 1 to 8 years). age normal was 9.6 5.3 years. A significant difference found between versus that control. In addition, controls, but there no marked persons those pancreatitis. 2.34 0.47 mm 2.84 0.67 mm,...