A5002945666- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Genomics and Phylogenetic Studies
- Advanced Glycation End Products research
- Bacteriophages and microbial interactions
- Urological Disorders and Treatments
- Microbial Community Ecology and Physiology
- Aquaculture disease management and microbiota
- Pharmaceutical and Antibiotic Environmental Impacts
- Aldose Reductase and Taurine
- Genetic diversity and population structure
- Microbial Metabolic Engineering and Bioproduction
- Diet and metabolism studies
- Urinary Tract Infections Management
- Insect Resistance and Genetics
- Bladder and Urothelial Cancer Treatments
- Plant Gene Expression Analysis
- Chromosomal and Genetic Variations
- CRISPR and Genetic Engineering
- Animal Genetics and Reproduction
- Biofuel production and bioconversion
- Cancer-related molecular mechanisms research
- Photosynthetic Processes and Mechanisms
- Plant Molecular Biology Research
- Semiconductor materials and devices
Beijing Academy of Agricultural and Forestry Sciences
2019-2025
Northeast Ohio Medical University
2025
Chinese Academy of Sciences
2010-2024
Harbin Institute of Technology
2018-2024
Huizhou University
2024
Kunming Third People's Hospital
2024
University of Chinese Academy of Sciences
2014-2024
Kunming Medical University
2024
Institute of Advanced Science Facilities, Shenzhen
2024
Sun Yat-sen University
2024
Xiaowen Sun and colleagues report the whole-genome sequencing of common carp, Cyprinus carpio. They also resequenced 33 representative accessions from a worldwide collection provide insights into population structure evolution. The carpio, is one most important cyprinid species globally accounts for 10% freshwater aquaculture production. Here we present draft genome domesticated C. carpio (strain Songpu), whose current assembly contains 52,610 protein-coding genes approximately 92.3%...
Background Date palm (Phoenix dactylifera L.), a member of Arecaceae family, is one the three major economically important woody palms—the two other palms being oil and coconut tree—and its fruit staple food among Middle East North African nations, as well many tropical subtropical regions. Here we report complete sequence data chloroplast (cp) genome based on pyrosequencing. Methodology/Principal Findings After extracting 369,022 cp sequencing reads from our whole-genome-shotgun data, put...
Abstract A complete and accurate genome sequence provides a fundamental tool for functional genomics DNA-informed breeding. Here, we assemble high-quality (contig N50 of 6.99 Mb) the apple anther-derived homozygous line HFTH1, including 22 telomere sequences, using combination PacBio single-molecule real-time (SMRT) sequencing, chromosome conformation capture (Hi-C) optical mapping. In comparison to Golden Delicious reference genome, identify 18,047 deletions, 12,101 insertions 14 large...
Date palm (Phoenix dactylifera L.) is a cultivated woody plant species with agricultural and economic importance. Here we report genome assembly for an elite variety (Khalas), which 605.4 Mb in size covers >90% of the (~671 Mb) >96% its genes (~41,660 genes). Genomic sequence analysis demonstrates that P. experienced clear genome-wide duplication after either ancient whole duplications or massive segmental duplications. Genetic diversity indicates stress resistance sugar metabolism-related...
Background Common carp (Cyprinus carpio) is one of the most important aquaculture species Cyprinidae with an annual global production 3.4 million tons, accounting for nearly 14% freshwater in world. Due to economical and ecological importance common carp, genomic data are eagerly needed genetic improvement purpose. However, there still no sufficient transcriptome available. The objective project sequence deeply provide well-assembled sequences research community. Result Transcriptome...
Hybridization drives rapid speciation by shaping novel genotypic and phenotypic profiles. Genomic incompatibility transcriptome shock have been observed in hybrids, although this is rarer animals than plants. Using the newly sequenced genomes of blunt snout bream ( Megalobrama amblycephala [BSB]) topmouth culter Culter alburnus [TC]), we focused on sequence variation gene expression changes reciprocal intergeneric hybrid lineages (F 1 –F 3 ) BSB × TC. A genome-wide transcriptional analysis...
Antibiotics and antibiotic resistance genes (ARGs) used in intensive animal farming threaten human health worldwide; however, the common resistome, ARG mobility, host composition different manures mixed manure composts remain unclear. In present study, metagenomic assembly cross-sample mapping were to comprehensively decipher resistome its potential mobility hosts composts.In total, 201 ARGs shared among (layer, broiler, swine, beef cow, dairy cow) accounted for 86-99% of total relative...
Abstract Symbiodinium are the photosynthetic endosymbionts for corals and play a vital role in supplying their coral hosts with products, forming nutritional foundation high-yield reef ecosystems. Here, we determine cryo-electron microscopy structure of photosystem I (PSI) supercomplex PSI core composed 13 subunits including 2 previously unidentified subunits, PsaT PsaU, as well peridinin-Chl / c -binding light-harvesting antenna proteins (AcpPCIs). The PSI–AcpPCI exhibits distinctive...
Diabetic bladder dysfunction is among the most common and bothersome complications of diabetes mellitus. While filling voiding problems have been reported, precise functional changes in diabetic bladders remain unclear. We investigated time dependent function streptozotocin induced rats.Cystometrograms detrusor muscle contractility were examined male age matched control Sprague-Dawley rats (Harlan, Indianapolis, Indiana) 3, 6, 9, 12 20 weeks after induction with streptozotocin.Diabetes...
The Amur ide (Leuciscus waleckii) is a cyprinid fish that widely distributed in Northeast Asia. Lake Dali Nur population inhabits one of the most extreme aquatic environments on Earth, with an alkalinity up to 50 mmol/L (pH 9.6), thus providing exceptional model which characterize mechanisms genomic evolution underlying adaptation environments. Here, we developed reference genome assembly for L. waleckii from Nur. Intriguingly, identified unusual expanded long terminal repeats (LTRs) higher...
Traditional Chinese medicine uses various herbs for the treatment of diseases thousands years and it is now time to assess characteristics effectiveness these medicinal plants based on modern genetic molecular tools. The herb Flos Lonicerae Japonicae (FLJ or Lonicera japonica Thunb.) used as an anti-inflammatory agent but chemical quality FLJ its efficacy has not been consistent. Here, we analyzed transcriptomes metabolic pathways evaluate active compounds in hope that this approach can be a...
Objective To review studies on diabetic bladder dysfunction (DBD), a common and bothersome complication of diabetes mellitus. Data sources We performed search the English literature through PubMed. The key words used were “diabetes” “bladder dysfunction” or “cystopathy”. Our own data perspective are included in discussion. Study selection Studies containing relevant to DBD selected. Because limited length this article, we also referenced reviews that contain comprehensive amalgamations...
Abstract Background The Northern snakehead (Channa argus), a member of the Channidae family Perciformes, is an economically important freshwater fish native to East Asia. In North America, it has become notorious as intentionally released invasive species. Its ability breathe air with gills and migrate short distances over land makes good model for bimodal breath research. Therefore, recent research focused on identification relevant candidate genes. Here, we performed whole genome...
Diabetic bladder dysfunction (DBD) is among the most common and bothersome complications of diabetes mellitus. Autonomic neuropathy has been counted as cause DBD. In present study, we compared alterations in neurogenically mediated contractile responses urinary rats with streptozocin-induced diabetes, 5% sucrose-induced diuresis, age-matched controls. Male Sprague-Dawley were divided into three groups: 9-wk diabetic rats, diuretic Micturition morphometric characteristics evaluated using...
Diabetic bladder dysfunction is a common complication of diabetes mellitus (DM) with poorly understood natural history. This study examined the temporal changes in function 3, 9, 12, and 20 wk after induction DM by streptozotocin (STZ) male C57BL/6 mice compared that age-matched diabetic treated insulin, 5% sucrose-induced diuretic mice, sham-treated control mice. Conscious cystometrograms were addition to measurements micturition cycle. Diabetes resulted decreased body weight. Bladder...
The natural history of diabetes mellitus-induced remodeling the urinary bladder is poorly understood. In this study, we examined temporal in diabetic and diuretic rats. Male Sprague-Dawley rats were divided into three groups: streptozotocin-induced diabetic, 5% sucrose-induced diuretic, age-matched control. Micturition morphometric characteristics evaluated using metabolic cages light-microscopic examination 4 days 1, 2, 3, 9 wk after induction. Digital image analysis was used to quantify...
Abstract Background Zunongwangia profunda SM-A87, which was isolated from deep-sea sediment, is an aerobic, gram-negative bacterium that represents a new genus of Flavobacteriaceae . This the first sequenced genome phylum Bacteroidetes Results The Z. SM-A87 has single 5 128 187-bp circular chromosome with no extrachromosomal elements and harbors 4 653 predicted protein-coding genes. produces large amount capsular polysaccharides possesses two polysaccharide biosynthesis gene clusters. It...
Diabetes mellitus causes diabetic bladder dysfunction. We identified the pathogenic roles of polyuria and hyperglycemia in dysfunction rats.A total 72 female Sprague-Dawley® rats were divided into 6 groups, including age matched controls, with sham urinary diversion, streptozotocin induced diabetes after diversion 5% sucrose diuresis diversion. Urinary was performed by ureterovaginostomy 10 days before induction. Animals evaluated 20 weeks or measured 24-hour drinking voiding volumes,...
Diabetic bladder dysfunction (DBD), a prevalent complication of diabetes mellitus (DM), is characterized by broad spectrum symptoms including urinary urgency, frequency, and incontinence. As DBD commonly diagnosed late, it important to understand the chronic impact DM on tissues. While changes in smooth muscle innervation have been reported diabetic patients, specialized epithelial lining bladder, urothelium (UT), largely unknown. Quantitative polymerase chain reaction analysis electron...
Saprotrophy on plant biomass is a recently developed nutrition strategy for Trichoderma. However, the physiology and evolution of this new still elusive. We report deep sequencing analysis genome Trichoderma longibrachiatum, an efficient cellulase producer. The 31.7-Mb genome, smallest among sequenced species, encodes fewer nutrition-related genes than saprotrophic T. reesei (Tr), including glycoside hydrolases nonribosomal peptide synthetase–polyketide synthase. Homology phylogenetic...