Mandana Sattari

ORCID: 0000-0002-9409-070X
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Endodontics and Root Canal Treatments
  • Oral Health Pathology and Treatment
  • Aldose Reductase and Taurine
  • Dental materials and restorations
  • Periodontal Regeneration and Treatments
  • Dental Implant Techniques and Outcomes
  • Pediatric health and respiratory diseases
  • Fish Biology and Ecology Studies
  • Energy and Environment Impacts
  • Immune Response and Inflammation
  • Mesenchymal stem cell research
  • Cancer Risks and Factors
  • Bone Metabolism and Diseases
  • S100 Proteins and Annexins
  • Iron Metabolism and Disorders
  • Reproductive Health and Contraception
  • Probiotics and Fermented Foods
  • Cervical Cancer and HPV Research
  • Cancer-related molecular mechanisms research
  • Bone Tissue Engineering Materials
  • Salivary Gland Disorders and Functions
  • Prenatal Substance Exposure Effects
  • MicroRNA in disease regulation
  • Pharmacological Effects and Toxicity Studies

Kashan University of Medical Sciences
2024-2025

University of Florida
2014-2025

Society of General Internal Medicine
2025

Florida College
2014-2025

Shahid Beheshti University of Medical Sciences
2013-2022

University of Guilan
2014-2022

Mercer University
2022

Mercer University Health Sciences Center
2022

Tarbiat Modares University
2022

Tabriz University of Medical Sciences
2011-2021

Background: MicroRNAs (miRNAs) are a group of small non‐coding RNAs that play an important role in the regulation gene expression. miRNA‐146a (miR‐146a), member miR‐146 family, is involved control inflammation. Periodontitis set chronic inflammatory disorders tissues surrounding teeth lead to breakdown alveolar bone and tooth loss. In this study, expression levels miR‐146a its targets, including tumor necrosis factor (TNF)‐α, interleukin (IL)‐1β, IL‐6, evaluated human patients with...

10.1902/jop.2015.150319 article EN Journal of Periodontology 2015-08-27

Background and aims.Lysozyme lactoferrin are salivary proteins which play an important role in innate defense mechanisms against bacteria.This study investigated the association of lysozyme concentrations with early childhood caries (ECC). Materials methods.This was carried out on 42 healthy children (age range, 36 to 71 months), whom 21 were free (CF) had ECC.Disposable needle-less syringes used collect unstimulated saliva from buccal labial vestibules.Fifteen who ECC treated completely...

10.15171/joddd.2015.022 article EN cc-by Journal of Dental Research Dental Clinics Dental Prospects 2015-06-10

Background: Triptans are used as antimigraine agents. Some cases of hepatotoxicity by triptans have been reported. However, the exact mechanism triptan-induced is not clear yet. Methods: In this study, cytotoxic effects rizatriptan were investigated in freshly isolated rat hepatocytes using accelerated cytotoxicity screening. We designed experiments to evaluate toxicity markers, such cell death, reactive oxygen species (ROS) formation, lipid peroxidation, mitochondrial membrane potential,...

10.1055/s-0042-110178 article EN Drug Research 2016-07-11

MicroRNA-146a (miR-146a) is a small noncoding RNA that plays critical role in the negative regulation of innate immune response, and dysregulation miR-146a has been associated with several inflammatory disorders. In generalized aggressive periodontitis (GAgP) degree clinical inflammation appears to be similar chronic periodontitis, and, this situation, age onset family history are important additional criteria for diagnosis. This study was performed evaluate level expressed gingival tissues...

10.1111/jre.12538 article EN Journal of Periodontal Research 2018-10-17

ABSTRACT Objective: The purpose of this study was to evaluate the effect different concentrations platelet-rich plasma (PRP) on proliferation undifferentiated periodontal ligament (PDL) fibroblasts. Materials and Methods: PDL fibroblasts were obtained from two healthy human premolar teeth cultured in Dulbecco's modified Eagle's medium. Cell wells divided into five groups. Experimental groups received 0.1%, 5%, or 50% PRP; positive negative control fetal bovine serum (FBS) 12% a medium...

10.4103/1305-7456.195165 article EN cc-by-nc-nd European Journal of Dentistry 2016-10-01

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Sadeghi R, Sattari M, Dehghan F, Akbari S. Interleukin-17 and interleukin-23 levels in gingival crevicular fluid of patients with chronic aggressive periodontitis. Central European Journal Immunology. 2018;43(1):76-80. doi:10.5114/ceji.2018.74876. APA Sadeghi, R., Sattari, M., Dehghan, F., & Akbari, (2018). Immunology, 43(1), 76-80. https://doi.org/10.5114/ceji.2018.74876 Chicago Rokhsareh, Mandana Fatemeh...

10.5114/ceji.2018.74876 article EN cc-by-nc-sa Central European Journal of Immunology 2018-01-01

A previously healthy man aged 50 years presented with malaise, anorexia, abdominal pain, nausea, vomiting, generalised jaundice, scleral icterus and dark urine. He was not on any prescription or over-the-counter medications, but reported drinking 4–5 energy drinks daily for 3 weeks prior to presentation. Physical examination revealed jaundice right upper quadrant tenderness. Laboratory studies were remarkable transaminitis evidence of chronic hepatitis C infection. Ultrasound scan...

10.1136/bcr-2016-216612 article EN cc-by-nc BMJ Case Reports 2016-11-01

Background: The high incidence of Non-Alcoholic Fatty Liver Disease (NAFLD) as a hepatic component metabolic syndrome is attributed to the ongoing rise in obesity rates. Given beneficial effects hydroxychloroquine (HCQ) on metabolism, there growing interest combining it with fisetin (FSN), natural product, treat NAFLD more effectively. Objective: efficacy and safety combined therapy FSN HCQ animal models were assessed, focusing liver function, insulin sensitivity, oxidative stress,...

10.2174/0109298673342421241126060049 article EN Current Medicinal Chemistry 2025-02-11

The purpose of this study was to compare substance P (SP) and calcitonin gene-related peptide (CGRP) expression in pulp tissue with clinically diagnosed symptomatic asymptomatic irreversible pulpitis. Healthy pulps acted as controls. Five normal 40 pulpitis (20 20 asymptomatic) were obtained from 45 different patients. SP CGRP determined by competition binding assays using enzyme immunoassay. anova Mann-Whitney tests used ascertain if there statistically significant differences between the...

10.1111/j.1747-4477.2009.00186.x article EN Australian Endodontic Journal 2009-11-05

Background: Cervical cancer, the third most prevalent cause of cancer in women worldwide, is associated with HPVs. The critical role E7 protein HPV-related malignancies has designated it as a strong contender for generating vaccines against HPV. Materials & methods: In this study, we developed novel live vaccine using recombinant Leishmania tarentolae expressing E7-green fluorescent (GFP) fusion protection mice HPV-associated tumors. order to transfect L. E7-GFP construct, pLEXSY-neo2 system...

10.2217/imt.12.110 article EN Immunotherapy 2012-11-01

When the first carpometacarpal joint of wrist is immobilized using an orthosis to combat effects osteoarthritis, atrophy thenar muscles may occur.The aim this study was evaluate muscle diameter and cross-sectional area, function, pain, before after being supplied with in patients grades 1 2 osteoarthritis compared a control group.Randomized clinical trial.A total 25 volunteer were randomized into two groups (an group group) randomization table. A visual analog scale, Michigan Hand...

10.1177/0309364616664149 article EN Prosthetics and Orthotics International 2016-09-20

Fungal growth in human foods and animal feeds causes profound damage indicating a general spoilage, nutritional losses, the formation of mycotoxins. Thirty apparently contaminated maize grass silage samples were analyzed for presence total fungi. Penicillium roqueforti isolated from all (100%) moldy on selective culture media. Furthermore, P. roqueforti-positive media subjected to toxin extraction toxins patulin, penicillic acid, mycophenolic roquefortin-C (ROQ-C) identified by means...

10.1177/0960327114565493 article EN Human & Experimental Toxicology 2015-03-05

Background: Personal breastfeeding behavior of physician mothers is associated with their clinical advocacy, which in turn impacts patients' behavior. Internists can play an important role advocacy as they usually come contact longitudinally. Objective: To explore the personal infant-feeding decisions and internal medicine (IM). Materials Methods: Physicians current or previous IM training were isolated from our "Breastfeeding Among Physicians" database. The data database gathered...

10.1089/bfm.2015.0151 article EN Breastfeeding Medicine 2016-02-26

Despite the vast use of herbal medicines in world, little is known about their pregnancy and attitudes pregnant women regarding safety during pregnancy.The aim this study was to evaluate toward medicine Iran.A questionnaire completed by 400 selected convenience sampling from postnatal prenatal wards two hospitals. Data were analyzed using SPSS software version 13.5. Chi2 test used analyze data.The median age 26.4 (± 5.2) years mean number pregnancies 1.9 0.98). The remedies positive 22.3%...

10.17795/jjnpp-3416 article EN Jundishapur Journal of Natural Pharmaceutical Products 2012-05-28

Maternal employment postpartum can have a powerful influence over infant-feeding behaviors. The objective of this cross-sectional online survey was to explore the intentions and behaviors convenience sample lawyer mothers. We compared our findings with those for physician mothers.Lawyers participated in an anonymous survey. To eliminate multiple births, only study subjects one child were reviewed inclusion analysis. used SPSS calculation descriptive statistics, Mann-Whitney test comparisons,...

10.14423/smj.0000000000000277 article EN Southern Medical Journal 2015-05-01

Background: The aim of the present study was to assess 2- and 4-h postendoscopic retrograde cholangiopancreatography (ERCP) serum amylase lipase levels for prediction post-ERCP, pancreatitis (PEP), their predictive cutoff values. Materials Methods: In this cross-sectional study, we evaluated before procedure, 2 h 4 after in patients with persisting abdominal pain, 24 afterward. A total 300 adult who underwent ERCP procedures from March 2014 June 2015 referral hospital Isfahan were studied....

10.4103/jrms.jrms_1100_17 article EN cc-by-nc-sa Journal of Research in Medical Sciences 2018-01-01

Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that intermediate metabolites amitriptyline produced by CYP450 are involved hepatic injury. Melatonin is an antiaging and antioxidant hormone synthesized from pineal gland. The aim present study was to evaluate protective role melatonin vitro model isolated rat hepatocytes. Methods: Markers such as cell viability,...

10.15171/apb.2015.046 article EN cc-by Advanced Pharmaceutical Bulletin 2015-09-19
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