A5030294808- Diet and metabolism studies
- Eating Disorders and Behaviors
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Physical Activity and Health
- Muscle metabolism and nutrition
- Dietary Effects on Health
- Health and Lifestyle Studies
- Ovarian cancer diagnosis and treatment
- Regulation of Appetite and Obesity
- Obesity and Health Practices
- Pharmacology and Obesity Treatment
- Nutrition and Health in Aging
- Consumer Attitudes and Food Labeling
- Biochemical Analysis and Sensing Techniques
- Behavioral Health and Interventions
- Adipose Tissue and Metabolism
- Diet, Metabolism, and Disease
- Cerebral Palsy and Movement Disorders
- Cancer-related molecular mechanisms research
- Estrogen and related hormone effects
- Menopause: Health Impacts and Treatments
- Cancer survivorship and care
- Metabolism, Diabetes, and Cancer
- PARP inhibition in cancer therapy
University of Alabama at Birmingham
2019-2025
Cedars-Sinai Medical Center
2022
Westmead Hospital
2020
University of Colorado Anschutz Medical Campus
2017-2019
State Street (United States)
2018
Purdue University West Lafayette
2015-2018
University of Colorado Denver
2017
University of South Florida
2006
Moffitt Cancer Center
2004-2006
St George's Hospital
1979-2005
Age-related increases in intermuscular adipose tissue (IMAT) impair muscle quality, decrease functional capacity, and promote several cardiometabolic inflammatory disorders. Whether these age-related alterations composition improve by consuming a high-protein (HP) diet with whole eggs are unclear. This parallel-design, randomized-controlled trial assessed the effects of 12-week eucaloric HP three per day (1.4 g protein kg−1 day−1) versus normal-protein void (NP, 0.8 on (IMAT), health,...
Abstract Background Bioelectrical impedance analysis (BIA) operates under the assumption that conductor has a uniform cylindrical shape. However, this may be violated if measures are taken in seated position, especially people with high waist circumference (WC). Aims The aims of research were to determine whether posture (supine, standing, and seated) WC affect agreement between BIA dual‐energy X‐ray absorptiometry (DXA) fat mass (FM) fat‐free (FFM). Materials & Methods Baseline data...
Abstract Background Identifying as someone who engages in health promoting behaviors like healthy eating and exercising may be associated with sustained engagement those behaviors, but reliable valid instruments are needed to improve the rigor of this research. Two studies were conducted (1) examine psychometric properties a four-item exerciser identity measure (4-EI) an adapted healthy-eater (4-HEI) (2) differences strengths across categories weight loss success. Methods Data from 1,709...
Long-term maintenance of weight loss requires sustained energy balance at the reduced body weight. This could be attained by coupling low total daily intake (TDEI) with expenditure (TDEE; flux), or pairing high TDEI TDEE (high flux). Within an environment characterized dense food and a lack need for movement, it may particularly difficult weight-reduced individuals to maintain in flux state. Most these will increase mass due inability sustain necessary level restriction. lead...
Intervention packages targeting obesity-related conditions often include multiple behavioral and pharmacological components, yet the independent synergistic effects of these strategies on disease progression remain largely unexplored. Adaptive interventions offer a structured approach to tailoring treatments based individual responses, but feasibility data in primary care settings are limited. The objective this pilot Sequential Multiple Assignment Randomized Trial (SMART) was investigate...
Abstract Objective Weight loss of ≥10% improves glucose control and may remit type 2 diabetes (T2D). High‐protein (HP) diets are commonly used for weight loss, but whether protein sources, especially red meat, impact loss‐induced T2D management is unknown. This trial compared an HP diet including beef a normal‐protein (NP) without meat body composition changes, in individuals with T2D. Methods A total 106 adults (80 female) consumed (40% protein) ≥4 weekly servings lean or NP (21% excluding...
Abstract Background Known risk alleles for epithelial ovarian cancer (EOC) account approximately 40% of the heritability EOC. Copy number variants (CNVs) have not been investigated as EOC in a large population cohort. Methods Single nucleotide polymorphism array data from 13 071 cases and 17 306 controls White European ancestry were used to identify CNVs associated with using rare admixture maximum likelihood test gene burden by-probe ratio test. We performed enrichment analysis at known...
Previously published findings from the Beef WISE Study (Beef’s Role in Weight Improvement, Satisfaction, and Energy) indicated equivalent weight loss between two energy-restricted higher protein (HP) diets: A HP diet with ≥4 weekly servings of lean beef (B; n = 60) a restricted all red meats (NB; 60). Long-term adherence to dietary prescriptions is critical for management but may be adversely affected by changes appetite, food cravings, satisfaction that often accompany loss. secondary...
Exogenous ketone ester and mixed with free acid formulations are rapidly entering the commercial marketspace. Short-term animal human studies using these products suggest significant potential for primary or secondary prevention of a number chronic disease conditions. However, questions need to be addressed by field optimal use in humans, including variable responses among available exogenous ketones at different dosages; frequency dosing; their tolerability, acceptability, efficacy...
Socioecological factors are associated with key health behaviors that critical for weight management, and major life events may disrupt engagement in these behaviors. However, the influence of socioecological on midst is not clear difficult to study due random sporadic nature their occurrence. The COVID-19 pandemic provided a unique opportunity event its impacts diet, physical activity, body weight.
This 12-month randomized, non-inferiority clinical trial sought to determine the impact of consuming soy protein as part an energy-restricted, high-protein diet on weight loss, body composition and cardiometabolic health.Seventy-one adults (58 female) with overweight or obesity (body mass index: 32.9 ± 3.6 kg m-2) were randomly assigned consume three servings (S) non-soy (NS) foods per day for 12 months. All participants completed a group-based behavioural loss program lasting 4 months (M4),...
Objective The objective of this randomized equivalence trial was to determine the impact consuming lean beef as part a high protein (HP) weight-reducing diet on changes in body weight, composition and cardiometabolic health. Methods A total 120 adults (99 female) with overweight or obesity (BMI: 35.7 ± 7.0 kg m−2) were randomly assigned consume either HP ≥4 weekly servings (B; n = 60) restricted all red meats (NB; during 16-week weight loss intervention. Results Body reduced by 7.8 5.9% B...
Increasing either protein or fiber at mealtimes has relatively modest effects on ingestive behavior. Whether and have additive interactive behavior is not known. Fifteen overweight adults (5 female, 10 male; BMI: 27.1 ± 0.2 kg/m2; aged 26 1 year) consumed four breakfast meals in a randomized crossover manner (normal (12 g) + normal (2 g), high (8 (25 g)). The amount of did influence postprandial appetite ad libitum energy intake lunch. In the fasting-state, visual food stimuli elicited...
Objective The brain's reward system influences ingestive behavior and subsequently obesity risk. Functional magnetic resonance imaging (fMRI) is a common method for investigating brain function. This study sought to assess the reproducibility of fasting‐state responses visual food stimuli using BOLD fMRI. Methods A priori regions interest included bilateral insula, amygdala, orbitofrontal cortex, caudate, putamen. Fasting‐state fMRI appetite assessments were completed by 28 women ( n = 16)...
Experimental cardiac infarction produced in dogs by coronary artery ligation has been used to investigate the value of macroscopic histochemical enzyme loss diagnosis myocardial at post-mortem. Creative phosphokinase and non-specific dehydrogenase methods gave best results but became positive only 5-6 hr after infarction. It is concluded that method limited autopsy practice.
Nuts have high energy and fat contents, but nut intake does not promote weight gain or obesity, which may be partially explained by their proposed satiety value. The primary aim of this study was to assess the effects consuming almonds versus a baked food on postprandial appetite neural responses visual stimuli. Twenty-two adults (19 women 3 men) with BMI between 25 40 kg/m² completed current during 12-week behavioral loss intervention. Participants consumed either 28 g whole, lightly salted...
Despite well-documented health benefits from exercise, a study on national trends in achieving the recommended minutes of physical activity guidelines has not improved since were published 2008. Peer interactions have been identified as critical factor for increasing population’s activity. The objective this is establishing criteria social influences that lead to exercise persistence. A system differential equations was developed projects over time. includes both and non-social impact...
Behavioral weight loss interventions can lead to an average of 5%-10% initial body weight, however there is wide individual variability in treatment response. Although built, social, and community food environments have potential direct indirect influences on (through their influence physical activity energy intake), these environmental factors are rarely considered as predictors variation loss.