Shakhnoz G. Khakimova

ORCID: 0000-0002-9491-0413
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Research Areas
  • Breast Cancer Treatment Studies
  • Breast Implant and Reconstruction
  • Reconstructive Surgery and Microvascular Techniques
  • Gastric Cancer Management and Outcomes
  • Breast Lesions and Carcinomas
  • Cancer Treatment and Pharmacology
  • Cancer Risks and Factors
  • Body Contouring and Surgery
  • Advanced Breast Cancer Therapies
  • Neuroendocrine Tumor Research Advances
  • Endometriosis Research and Treatment
  • Radiopharmaceutical Chemistry and Applications
  • HER2/EGFR in Cancer Research
  • Prostate Cancer Treatment and Research
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Body Image and Dysmorphia Studies
  • Endometrial and Cervical Cancer Treatments
  • Cancer and Skin Lesions

Tashkent Pediatric Medical Institute
2021-2025

Peoples' Friendship University of Russia
2025

Sechenov University
2025

Research Medical Center
2024

Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology
2021

P.A. Hertzen Moscow Oncology Research Institute
2019-2021

Применение биопсии «сторожевого» лимфатического узла (БСЛУ) при раке молочной железы (РМЖ) представляет собой минимально травматичную манипуляцию, которая является золотым стандартом диагностики регионарного лимфоколлектора и альтернативой аксиллярной лимфодиссекции, что позволяет избежать, в первую очередь, таких осложнений как контрактура плечевого сустава, лимфедема руки. Данный обзор литературы направлен на анализ результатов БСЛУ у пациентов с первоначально cN+ статусом РМЖ, которых...

10.37469/0507-3758-2024-70-6-1040-1047 article RU cc-by-nc-nd Voprosy Onkologii 2025-01-22

Disease stage and especially condition of the sentinel lymph node (SLN) assessed in patients with breast cancer prior to treatment are among most important prognostic factors. SLN is first regional system receiving outflow from primary tumor. biopsy blue dye gradually replaced traditional axillary dissection as standard early cancer. In recent years, technique contrast-enhanced sonography microbubble contrast agents for examination has been studied both animal human trials. Aim review...

10.17650/2782-3202-2024-4-4-111-118 article EN cc-by MD-Onco 2025-01-16

Despite advances in the early diagnosis of breast cancer (BC), identification locally advanced forms continues to be relevant. This is a complex category patients whose treatment includes use various methods with significant medical and economic costs, long-term rehabilitation. A particular difficulty cases progression forms. Patients BC require multidisciplinary approach. In absence an effect after neoadjuvant drug impossibility performing surgical intervention, are treated induction...

10.26442/18151434.2024.4.202874 article EN Journal of Modern Oncology 2025-02-18

Background. The surgical stage remains the main one in combined and complex treatment of breast cancer. Radical mastectomy reconstructive plastic surgery are option for vast majority patients. Radiation therapy can lead to development complications after reconstruction, vice versa, reconstructed mammary gland cause technical difficulties radiologist properly adjust required dose irradiation. Aim — choose optimal method reconstruction using various implants, as well endoprostheses minimize...

10.15690/vramn7186 article EN Annals of the Russian academy of medical sciences 2024-06-11

Breast reconstruction with a thoracodorsal flap (TDF) in combination tissue expander/implant is wellestablished technique. The purpose of the study was to present current data on results delayed breast and expander after combined/complex treatment patients cancer. Material methods . search for relevant sources carried out PubMed, Cochrane Library, E-library systems, publications from 2014 2022 were studied. Delayed using TDF reliable method group who have previously undergone radical...

10.52581/1814-1471/90/01 article EN cc-by Issues of Reconstructive and Plastic Surgery 2024-12-01

Neuroendocrine prostate cancer is a rare and aggressive with poor prognosis. This type of often diagnosed at an advanced stage exhibits rapid resistance to standard therapeutic methods. Taking into account the low occurrence this phenomenon, description poorly differentiated neuroendocrine (small cell) extremely forms given.

10.33667/2078-5631-2024-27-55-59 article EN Medical alphabet 2024-12-16

To study the state of systemic immunity and local before during chemotherapy in patients with gastric adenocarcinoma. From 2017 to 2018 at Tashkent city branch Republican specialized scientific practical medical center oncology radiology 20 primary metastatic adenocarcinoma received chemotherapy. The sampling biological material (peripheral blood, tumor tissue) was carried out twice (before treatment first control examination, after 3 courses). percentage degree infiltration tissue by...

10.37547/tajmspr/volume03issue03-03 article EN cc-by The American Journal of Medical Sciences and Pharmaceutical Research 2021-03-27

Introduction. Arming gynecological oncology with modern chemotherapy schemes, elements of aggressive oncosurgery, it is possible to achieve an increase in the number cured patients locally advanced forms cervical cancer (CC), providing improvement immediate and long-term results treatment. The proposed method surgical treatment choice for (stages IIA–IIIB). Purpose study. Introduction into clinical practice IIA–IIIB stages cancer. Material methods. Long-term 155 morphologically verified...

10.33667/2078-5631-2022-31-50-54 article EN cc-by Medical alphabet 2023-01-12

Background: To evaluate relapses in patients with breast cancer (BC) who underwent radical subcutaneous mastectomy simultaneous reconstruction. Methods: From 2013 to 2017 mastectomies were performed various types of reconstructions 472 BC. Reconstruction was carried out by autotissues (15%), as well expanders, followed replacement endoprostheses, a combination endoprostheses or without patch (85%). Distribution patients' stage: 0 – 5,5%, I 30,7%, IIA 28,6%, IIB 14,8%, IIIA 13,8%, IIIC 4,9 %,...

10.1093/annonc/mdz098.019 article EN publisher-specific-oa Annals of Oncology 2019-05-01

Squamous cell carcinoma of the breast is a rare, aggressive tumor with poor prognosis. To date, due to low incidence morbidity, there no single concept in complex treatment this pathology. The article describes case 49-year-old patient after surgical squamous left from 2019 on anamnesis. A year later progression disease underwent removal chest wall resection IIIV ribs, allo- and autoplasty, axillary lymphadenectomy left. In most cases, surgery, but role adjuvant chemotherapy, radiation...

10.26442/18151434.2020.4.200496 article EN Journal of Modern Oncology 2021-02-17
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