A5005229888- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Influenza Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Vaccine Coverage and Hesitancy
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Cervical Cancer and HPV Research
- Gestational Diabetes Research and Management
- Reproductive System and Pregnancy
- COVID-19 Impact on Reproduction
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Respiratory viral infections research
- Immune responses and vaccinations
- COVID-19 epidemiological studies
- Hepatitis B Virus Studies
- Multiple Sclerosis Research Studies
- Prenatal Screening and Diagnostics
- Genital Health and Disease
- Parvovirus B19 Infection Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Bacterial Infections and Vaccines
- Infectious Encephalopathies and Encephalitis
- Dermatological and COVID-19 studies
Norwegian Institute of Public Health
2016-2025
University of Oslo
2013-2022
VID Specialized University
2022
Oslo University Hospital
2005-2022
University of Edinburgh
2022
Zealand University Hospital
2022
Faculty of Public Health
2022
University of Iceland
2022
Nasjonalforeningen for Folkehelsen
2015
UiT The Arctic University of Norway
2013
A recent study showed that nulliparous women who develop preeclampsia had low concentrations of vitamin D in serum sampled midpregnancy. The aim the present was to estimate association between intake during pregnancy and risk 23,423 pregnant taking part Norwegian Mother Child Cohort Study.Participating answered questionnaires at gestational week 15 (general health questionnaire), 22 (food frequency 30 questionnaire). Pregnancy outcomes were obtained from Medical Birth Registry. Nutrient...
During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe illness. This concern was complicated by questions about vaccine safety in that raised anecdotal reports of fetal deaths after vaccination.We explored vaccination linking Norwegian national registries and medical consultation data to determine diagnosis, status, birth outcomes, background information before, during, pandemic. We used Cox regression models estimate hazard ratios death, with gestational day as...
<h2>Summary</h2><h3>Background</h3> Long-term mental and physical health consequences of COVID-19 (long COVID) are a persistent public concern. Little is still known about the long-term non-hospitalised patients with varying illness severities. Our aim was to assess prevalence adverse symptoms among individuals diagnosed in general population by acute infection severity up 16 months after diagnosis. <h3>Methods</h3> This observational follow-up study included seven prospectively planned...
The aim of the current study was to estimate sex- and age-specific incidence rates chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) using population-based registry data. CFS/ME is a debilitating condition with large impact on patients their families. etiology unknown, distribution disease in general population has not been well described.
Abstract Human birth weight is subject to stabilizing selection; babies born too small or large are less likely survive. Particular combinations of maternal/fetal immune system genes associated with pregnancies where the ≤5th centile, specifically an inhibitory maternal KIR AA genotype a paternally derived fetal HLA-C2 ligand. We have now analyzed and HLA-C at opposite end spectrum. Mother/baby pairs (n = 1316) were genotyped for as well HLA-C. Presence maternal-activating KIR2DS1 gene was...
Physical, psychological and cognitive symptoms have been reported as post-acute sequelae for COVID-19 patients but are also common in the general uninfected population. We aimed to calculate excess risk identify patterns of 22 up 12 months after COVID-19. followed more than 70,000 adult participants an ongoing cohort study, Norwegian Mother, Father Child Cohort Study (MoBa) during pandemic. Infected non-infected registered presence different March 2021. One year infection, 13 were associated...
Background Many signals of menstrual disturbances as possible side effects vaccination against COVID-19 have been reported. Our objective was to estimate the association between and occurrence such among women aged 18-30 in Norway.Methods We used mobile-phone questionnaires collect reports from 5688 years, participating population-based Norwegian Young Adult Cohort. estimated relative risk according a self-controlled case-series design, using first six weeks after exposed period. examined...
The SARS-CoV-2 Omicron variant has more than 15 mutations in the receptor binding domain of Spike protein enabling increased transmissibility and viral escape from antibodies vaccinated individuals. It is unclear how vaccine immunity protects against infection. Here we show that participants at a super-spreader event have robust recall response humoral pre-existing cellular induced by vaccines, an emergent de novo T cell to non-Spike antigens. Individuals with breakthrough infections...
Objectives To compare the risk of hyperemesis gravidarum in second pregnancies women with and without their first pregnancy, to determine if this changes paternity or interval between deliveries. Design Cohort study. Setting Data from population‐based Medical Birth Registry Norway, 1967–1998. Sample All registry records singleton delivery, a total 547,238 women. Methods The relative delivery was estimated as odds ratios (ORs) logistic regression models, controlling for potential confounding...
The Norwegian immunisation register, SYSVAK, is a national electronic register. It became nationwide in 1995. major aim was to register all vaccinations the Childhood Immunisation Programme ensure that children are offered adequate vaccination according schedule programme, and secure high coverage. Notification SYSVAK mandatory, based on personal identification numbers. This allows follow up of individual schedules linkage data other health registers for information outcome diagnoses, such...
The association between pregnancy complications and women's later cardiovascular disease has, primarily, been evaluated in studies lacking information on important covariates. This report evaluates the prospective associations pregnancy-related risk factors (preeclampsia/eclampsia, gestational hypertension, pregestational diabetes mellitus, preterm delivery, fetal growth restriction) pharmacologically treated hypertension within 10 years after pregnancy, while adjusting for a wide range of...
Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels antibodies receptor-binding domain ancestral SARS-CoV-2 (RBDwt). However, predictive value for protection against new variants concern (VOCs) has not been firmly established. Here, we bead-based arrays and flow cytometry binding spike proteins domains (RBDs) from VOCs in 12,000 serum samples. Effects sera on RBD-ACE2 interactions were measured as a proxy neutralizing antibodies. The samples obtained...
Many signals of menstrual disturbances as possible side effects vaccination against COVID-19 have been reported. Our objective was to compare the risk before and after among women aged 18-30 years in Oslo, Norway. We used electronic questionnaires collect reports from 3972 years, participating population-based Norwegian Young Adult Cohort. examined occurrence (heavier bleeding than usual, prolonged bleeding, shorter interval between menstruations, longer spot bleedings, stronger pain during...
Abstract Background The N orwegian M other and C hild ohort S tudy ( MoBa ), a prospective population‐based pregnancy cohort, is valuable database for studying causes of pre‐eclampsia. Pre‐eclampsia data in come from the edical B irth R egistry orway MBRN ); thus, we wanted to study validity pre‐eclampsia registration women. Methods We selected all pregnancies with registered n = 4081) random control group 2000) without registrations. After excluding two delivery units not participating one...
Objective Vaccine against human papillomavirus (HPV) has been offered free of charge to all 12-year-old girls in Norway since 2009. Nevertheless, the uptake HPV vaccine is lower than for other childhood vaccines. The aim this study was examine whether parental education and income are associated with initiation completion vaccination. Design Nationwide register-based study. Setting Publicly funded immunisation programme Norway. Participants 91 405 born between 1997 1999 registered Norwegian...
Vaccination has been suggested to be involved in the aetiology of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). HPV vaccine was introduced Norwegian Childhood Immunisation Programme and offered 12year old girls from 2009. We studied association between vaccination risk CFS/ME also assessed medical history relation both uptake.Individual data national registries, including Population Registry, Patient Registry were linked using unique personal identification number. Yearly...
BackgroundOlder age is associated with poorer outcomes to COVID-19 infection. The Norwegian Institute of Public Health established a longitudinal cohort adults aged 65–80 years study the effects pandemic. Here we describe characteristics in general, and specifically immune responses at baseline after primary booster vaccination subset blood samples, epidemiological factors affecting these responses.Methods4551 participants were recruited, humoral (n=299) cellular (n=90) measured before two...
Objective Pre‐eclampsia, recurrent miscarriage and infertility may all partly be caused by unsuccessful placentation early in pregnancy. If so, one will expect these disorders to associated population studies. The aim of the present investigation was estimate risk pre‐eclampsia women with infertility. Design Cohort study. Setting Norwegian Mother Child Study (MoBa), a large population‐based pregnancy cohort. Sample sample consisted 20 846 singleton pregnancies nulliparous participating MoBa,...
Background: The inverse association between prenatal smoking and preeclampsia is puzzling, given the increased risks of prematurity low birthweight associated with both preeclampsia. We analyzed Norwegian Mother Child Birth Cohort (MoBa) to determine whether associations varied by timing smoking. Methods: conducted an analysis 74,439 singleton pregnancies completed second- third- trimester questionnaires. Active passive smoke exposure were determined maternal self-report, covered period...