A5024330715- Dialysis and Renal Disease Management
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Central Venous Catheters and Hemodialysis
- SARS-CoV-2 and COVID-19 Research
- Organ Donation and Transplantation
- Health Systems, Economic Evaluations, Quality of Life
- Renal and Vascular Pathologies
- Liver Disease and Transplantation
- Colorectal Cancer Treatments and Studies
- Transplantation: Methods and Outcomes
- Moyamoya disease diagnosis and treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Heparin-Induced Thrombocytopenia and Thrombosis
- Systemic Lupus Erythematosus Research
- Long-Term Effects of COVID-19
- Pregnancy and Medication Impact
- Autoimmune and Inflammatory Disorders Research
- Muscle and Compartmental Disorders
- Nutrition and Health in Aging
- Liver Diseases and Immunity
- Genetic and Kidney Cyst Diseases
- Cardiac pacing and defibrillation studies
- CNS Lymphoma Diagnosis and Treatment
- Streptococcal Infections and Treatments
Henry Ford Hospital
2025
Tokyo Women's Medical University
2022-2025
University of Tokyo Hospital
2019-2024
Organ Technologies (Japan)
2023-2024
Shonan Kamakura General Hospital
2018-2023
The University of Tokyo
2016-2022
For peritonitis, a serious complication of peritoneal dialysis (PD), we investigated the relation between duration from sign (PD effluent abnormalities) to treatment with appropriate antibiotics (ST time) and catheter removal. 62 PD hospital patients, data PD-related peritonitis (n = 109) were collected retrospectively. We examined ST time removal times using univariate multivariate analyses. The rate in delayed group (≥ 24 h) was higher than that early (< (38 vs. 16%, p 0.02). Concomitant...
<title>Abstract</title> Living kidney donors typically experience approximately a 30% reduction in function after donation, although the degree of varies among individuals. This study aimed to develop machine learning (ML) model predict serum creatinine (Cre) levels at one year post-donation using preoperative clinical data, including kidney-, fat-, and muscle-volumetry values from computed tomography. A total 204 living were included. Symbolic regression via genetic programming was employed...
Immune checkpoint inhibitors (CPIs), including pembrolizumab, are becoming common oncological treatments. CPIs have been associated with a significant risk of developing immune-related adverse events (irAEs), such as nephritis and interstitial nephritis. However, the occurrence glomerulonephritis has only rarely reported. We herein present case 75-year-old woman non-small cell lung carcinoma (NSCLC) who developed proteinuria microscopic hematuria during treatment pembrolizumab. Renal biopsy...
Recent developments in intensive desensitization protocols have enabled kidney transplantation human leukocyte antigen (HLA)-sensitized recipients. However, cases of active antibody-mediated rejection (AABMR), when they occur, are difficult to manage, graft failure being the worst-case scenario. We aimed assess impact our and AABMR treatment regimen identify risk factors for disease progression. Among 849 patients who underwent living-donor between 2014 2021 at institution, 59 were diagnosed...
Myostatin, which is known as a negative skeleton muscle regulator, associated with mortality in maintenance hemodialysis patients. However, the significance of serum myostatin concentrations at dialysis initiation has not been established. We investigated relation between and or hospitalization within 1 year incident
Frailty is associated with mortality in maintenance dialysis patients. For incident patients, we used the clinical frailty scale (CFS) to investigate as related or hospitalization within 2 years. We retrospectively reviewed medical records of patients initiating hemodialysis peritoneal during 2016-2018. Based on those records, two nurses independently a 9-point CFS (1 = "Very fit" 9 "Terminally ill") assess each patient's at initiation. Patients mean value 5 higher were classified into frail...
Background Kidney transplantation is a well‐established alternative in renal replacement therapy. Compared with hemodialysis, low‐immunological‐risk kidney can reduce the medical treatment costs associated end‐stage disease. However, there are few reports on whether high‐immunological‐risk reduces financial burden governments. We investigated of comparison cost hemodialysis Japan. Methods compared those hemodialysis. 15 patients who underwent crossmatch‐positive and/or donor‐specific...
Catheter-related infections such as exit site infection (ESI) and tunnel (TI) are major causes of peritoneal dialysis (PD) discontinuation. For ESI/TI treatment, catheter diversion procedure (CDP) with exit-site renewal for salvage presents an alternative to removal. Nevertheless, CDP capability improving PD survival remains unclear.We retrospectively reviewed our hospital patients who started during 2001-2019 (n=148): 33 treated by (CDP group) 115 using conservative therapy or none (non-CDP...
Pregnancy in kidney transplantation (KT) recipients has been challenging because of the high risk maternal, fetal, and renal complications. Although patients with immunoglobulin A nephropathy (IgAN)-chronic disease (CKD) are at a for hypertension pregnancy (HIP), maternal KT IgAN as etiology remains unclear. We retrospectively reviewed medical records pregnant who delivered our hospital. The incidence fetal complications impact on allografts between group primary other diseases were...
Diarrhea is a common complication in kidney transplant recipients. Common causes of diarrhea include infection, side effect from medication, rejection, and malignancy. A less but important cause de novo inflammatory bowel disease (IBD). This unexpected, as these patients are already immunosuppressed. Herein, we present the case 45-year-old man with end-stage because focal segmental glomerulosclerosis who underwent preemptive transplantation, his mother donor. His immunosuppressive regimen...
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Abstract Introduction: For peritonitis, a serious complication of peritoneal dialysis (PD), we investigated the relation between duration from sign (PD effluent abnormalities) to treatment with appropriate antibiotics (ST time) and catheter removal. Design, setting, participants: 62 PD hospital patients, data PD-related peritonitis (n=109) were collected retrospectively. We examined ST time removal times using univariate multivariate analyses. Results: The rate in delayed group (>=24 hr)...