Lucinda Wynne

ORCID: 0000-0002-9737-9293
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About
Contact & Profiles
Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Cardiac Imaging and Diagnostics
  • Vascular Procedures and Complications
  • vaccines and immunoinformatics approaches
  • Infection Control and Ventilation
  • Cardiac, Anesthesia and Surgical Outcomes
  • COVID-19 epidemiological studies
  • T-cell and B-cell Immunology
  • COVID-19 and Mental Health
  • Single-cell and spatial transcriptomics
  • Poisoning and overdose treatments
  • Acute Kidney Injury Research
  • Ultrasound in Clinical Applications
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Nitric Oxide and Endothelin Effects
  • Long-Term Effects of COVID-19
  • Radiomics and Machine Learning in Medical Imaging
  • Airway Management and Intubation Techniques
  • Gastric Cancer Management and Outcomes
  • Hemodynamic Monitoring and Therapy
  • SARS-CoV-2 detection and testing
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Infective Endocarditis Diagnosis and Management

Central and North West London NHS Foundation Trust
2024

Barts Health NHS Trust
2020-2024

Evolved Analytics (United States)
2024

William Harvey Research Institute
2023-2024

Queen Mary University of London
2023-2024

National Health Service
2024

St Bartholomew's Hospital
2020-2021

Contrast-induced nephropathy (CIN), also known as contrast-associated acute kidney injury (CA-AKI) underlies a significant proportion of the morbidity and mortality following coronary angiographic procedures in high-risk patients remains unmet need. In pre-clinical studies inorganic nitrate, which is chemically reduced vivo to nitric oxide, renoprotective but this observation yet be translated clinically. study, efficacy nitrate prevention CIN presenting with syndromes (ACS) reported.

10.1093/eurheartj/ehae100 article EN cc-by European Heart Journal 2024-03-21

BACKGROUND: Patients with previous coronary artery bypass grafting often require invasive angiography (ICA). However, for these patients, the procedure is technically more challenging and has a higher risk of complications. Observational studies suggest that computed tomography cardiac (CTCA) may facilitate ICA in this group, but not been tested randomized controlled trial. METHODS: This study was single-center, open-label trial assessing benefit adjunctive CTCA patients referred ICA. were...

10.1161/circulationaha.123.064465 article EN Circulation 2023-09-29

<ns3:p><ns3:bold>Background</ns3:bold>: Most biomedical research has focused on sampling COVID-19 patients presenting to hospital with advanced disease, less focus the asymptomatic or paucisymptomatic. We established a bioresource serial of health care workers (HCWs) designed obtain samples before and during mainly mild follow-up evaluate quality duration immune memory.</ns3:p><ns3:p> <ns3:bold>Methods</ns3:bold>: conducted prospective study HCWs from three sites in London, initially at...

10.12688/wellcomeopenres.16051.2 preprint EN cc-by Wellcome Open Research 2020-10-12

<ns4:p><ns4:bold>Background</ns4:bold>: Most biomedical research has focused on sampling COVID-19 patients presenting to hospital with advanced disease, less focus the asymptomatic or paucisymptomatic. We established a bioresource serial of health care workers (HCWs) designed obtain samples before and during mainly mild follow-up evaluate quality duration immune memory.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: conducted prospective observational study HCWs from three sites in London,...

10.12688/wellcomeopenres.16051.1 preprint EN cc-by Wellcome Open Research 2020-07-28

Article1 July 1950THERAPY OF ACUTE BARBITURATE POISONING: REPORT THREE CASESMARCEL ROCHE, M.D., LYMAN C. WYNNE, DONALD M. HASKINS, M.D.MARCEL M.D.Search for more papers by this author, authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-1-73 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe following cases are believed be of interest because: (1) They illustrate recovery from...

10.7326/0003-4819-33-1-73 article EN Annals of Internal Medicine 1950-07-01

BACKGROUND: In patients with previous coronary artery bypass grafting, computed tomography cardiac angiography (CTCA) before invasive (ICA) was demonstrated in the BYPASS-CTCA trial (Randomized Controlled Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Bypass Surgery Patients) reduce procedure time and incidence of contrast-associated acute kidney injury, greater levels patient satisfaction. Patient-related outcomes, utilization further...

10.1161/circinterventions.124.014142 article EN Circulation Cardiovascular Interventions 2024-11-25
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