Ruth Parker
A5003388009- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Health Literacy and Information Accessibility
- T-cell and B-cell Immunology
- Long-Term Effects of COVID-19
- Healthcare Systems and Technology
- Telemedicine and Telehealth Implementation
- Single-cell and spatial transcriptomics
- Infection Control and Ventilation
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Patient Satisfaction in Healthcare
University of Cambridge
2020-2021
Abstract Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some individuals may clear subclinical infection before seroconversion. T cells can contribute the rapid clearance of SARS-CoV-2 and other infections 1–3 . Here we hypothesize pre-existing memory cell responses, cross-protective against (refs. 4–11 ), would expand in vivo support viral control, aborting infection....
BackgroundWe hypothesised that host-response biomarkers of viral infections might contribute to early identification individuals infected with SARS-CoV-2, which is critical breaking the chains transmission. We aimed evaluate diagnostic accuracy existing candidate whole-blood transcriptomic signatures for infection predict positivity nasopharyngeal SARS-CoV-2 PCR testing.MethodsWe did a nested case-control study among prospective cohort health-care workers (aged ≥18 years) at St Bartholomew's...
<ns3:p><ns3:bold>Background</ns3:bold>: Most biomedical research has focused on sampling COVID-19 patients presenting to hospital with advanced disease, less focus the asymptomatic or paucisymptomatic. We established a bioresource serial of health care workers (HCWs) designed obtain samples before and during mainly mild follow-up evaluate quality duration immune memory.</ns3:p><ns3:p> <ns3:bold>Methods</ns3:bold>: conducted prospective study HCWs from three sites in London, initially at...
<ns4:p><ns4:bold>Background</ns4:bold>: Most biomedical research has focused on sampling COVID-19 patients presenting to hospital with advanced disease, less focus the asymptomatic or paucisymptomatic. We established a bioresource serial of health care workers (HCWs) designed obtain samples before and during mainly mild follow-up evaluate quality duration immune memory.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: conducted prospective observational study HCWs from three sites in London,...