A5084877938- Genomics and Phylogenetic Studies
- Molecular Biology Techniques and Applications
- Helicobacter pylori-related gastroenterology studies
- Genetic factors in colorectal cancer
- Oral microbiology and periodontitis research
- RNA modifications and cancer
- Legume Nitrogen Fixing Symbiosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Chromium effects and bioremediation
- Bacteriophages and microbial interactions
- Aquaculture disease management and microbiota
- Plant-Microbe Interactions and Immunity
- Arsenic contamination and mitigation
- Gut microbiota and health
- RNA and protein synthesis mechanisms
- Metal Extraction and Bioleaching
- Dental Health and Care Utilization
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Bacillus and Francisella bacterial research
- Burkholderia infections and melioidosis
- Veterinary medicine and infectious diseases
- Gene expression and cancer classification
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Vibrio bacteria research studies
Instituto Politécnico Nacional
2012-2025
Universidad Nacional Autónoma de México
2016
Biofouling and biocorrosion in oil pipelines are serious problems capable of causing expensive, irreparable losses. For a better understanding processes, several lines evidence required, not least experimental considerations that emulate natural conditions inside pipelines. Herein, an omics approach is used to unveil the microbial involvement deterioration electrochemical process on X52 steel with Shewanella (SW), pipeline microbiota (AK), mixed culture (AK5), latter two obtained from sludge...
ABSTRACT This study presents the draft genomes of three strains " Burkholderia sola" isolated from Phaseolus vulgaris L. trap plants and rhizosphere Coffea arabica in Mexico.
This study analyzed the loss of heterozygosity (LOH) effect on gastric cancer (GC) tumor samples from 21 Mexican patients, including diffuse (DGC) and intestinal (IGC) subtypes, as well non-atrophic gastritis (NAG, control). Whole-genome high-density arrays were performed, LOH regions identified among tissue samples. The differences in affected chromosomes established groups, with 6 8 primarily DGC 3, 16, 17 IGC. Functional pathway analysis revealed involvement cancer-associated processes,...
Background: The metabolome of COVID-19 patients has been studied sparsely, with most research focusing on a limited number plasma metabolites or small cohorts. This is the first study to test saliva in comprehensive way, revealing patterns significantly linked disease and severity, highlighting saliva’s potential as non-invasive tool for pathogenesis diagnostic studies. Methods: We included 30 asymptomatic subjects no prior infection vaccination, 102 mild SARS-CoV-2 infection, 61...
Several Cupriavidus and Burkholderia strains from the north of Mexico were isolated during description strains. alkaliphilus , plantarum agave later described as novel species. Next, Genomic Encyclopedia Bacteria Archaea project retrieved genome sequences several above Standard comparative genomic analysis showed that C. MLR2-44 was taxonomically misclassified. This strain, Zea mays rhizosphere, analysed by average nucleotide identity (ANI), revealing nantongensis closest species (95.6%)....
In the present study, strain Rhizopus oryzae EMM was isolated from germinated autochthonous red maize seeds, which were harvested in a region of San Diego-Buenavista, Papalotla, Tlaxcala, Mexico, where cobs with fungal infections have been observed. This caused wilting seedlings. Pseudomonas protegens EMM-1 tested for its ability to inhibit R. EMM, both culture media and association plantlets. P. inhibited growth under all conditions explored. The associated plants evaluated hydroponic...
Chronically homeless adults (CHA) often face limited healthcare access, poor nutrition, frequent substance use, and close contact with stray animals. These factors can significantly alter their oral microenvironment. This study aimed to characterize the microbiota of this vulnerable understudied population. We analyzed saliva samples from 60 chronically men 40 asymptomatic no history homelessness, all living in Mexico City. DNA was extracted, V1-V3 regions 16S rRNA gene were sequenced....
Cupriavidus is a genus of bacteria that inhabit diverse ecological niches, including plant-associated and nodulating species. A previous survey legume plants in the south Mexico resulted isolation several bacteria. This present study describes two strains isolated from nodules Leucaena sp. Arachis growing cacao field Chiapas, Mexico. Both (LEh25 T LEh21) shared identical 16S rRNA gene sequences 98.4% identity with oxalaticus Ox1 . However, silico average nucleotide (ANI) digital DNA-DNA...
During the isolation of bacteria from Agave L. rhizosphere in northeast Mexico, four strains with similar BOX-PCR patterns were collected. The 16S rRNA gene sequences all very to each other and that type Cupriavidus metallidurans CH34T (98.49 % sequence similarity) necator N-1T (98.35 %). genome strain ASC-9842T was sequenced compared those species. ANIb ANIm values most closely related species lower than 95%, while silico DNA-DNA hybridization also much 70 %, consistent proposal they...
Worldwide, gastric cancer (GC) is estimated to be the fifth most common type of in both sexes, ranking sixth for new cases, with >640,850 cases per year, and fourth terms mortality rate. Cancer presents numerical structural alterations chromosomes, often through gains losses regions. In GC, there are multiple genetic alterations, which those located cytoband 8q24 have been frequently described; essential genes present this cytoband, regulating homeostasis crucial biological processes, such...
Abstract Background RNA sequencing (RNA-seq) is a common and widespread biological assay, an increasing amount of data generated with it. In practice, there are large number individual steps researcher must perform before raw RNA-seq reads yield directly valuable information, such as differential gene expression data. Existing software tools typically specialized, only performing one step–such alignment to reference genome–of larger workflow. The demand for more comprehensive reproducible...
The post-nutritional intervention modulation of miRNA expression has been previously investigated; however, post-acute dietary-ingestion-related dynamics in individuals with obesity and insulin resistance (IR) are unknown. We aimed to determine the acute effects protein ingestion from different dietary sources on postprandial metabolic response, amino acid levels, circulating adults IR. This clinical trial included IR who consumed (1) animal-source (AP; calcium caseinate) or (2)...
Phosphate metabolism was studied to determine whether polyphosphate (polyP) pools play a role in the enhanced resistance against Cd2+ and metal-removal capacity of Cd2+-preadapted (CdPA) Methanosarcina acetivorans. Polyphosphate kinase (PPK), exopolyphosphatase (PPX) phosphate transporter transcript levels their activities increased CdPA cells compared control (Cnt) cells. K+ inhibited recombinant Ma-PPK activated Ma-PPX, whereas divalent cations both enzymes. Metal-binding polyP...
Studies on the role of oral microbiome in SARS-CoV-2 infection and severity disease are limited. We aimed to characterize bacterial communities present saliva patients with varied COVID-19 learn if there differences characteristics among clinical groups. included 31 asymptomatic subjects no previous or vaccination; 176 mild respiratory symptoms, positive negative for infection; 57 that required hospitalization because severe oxygen saturation below 92%, 18 fatal cases COVID-19. Saliva...
Gastric cancer (GC) is a common malignancy with the highest mortality rate among diseases of digestive system, worldwide. The present study GC alterations crucial to understanding tumor biology and establishment important aspects prognosis treatment response. In study, DNA from Mexican patients diffuse (DGC), intestinal (IGC) or non‑atrophic gastritis (NAG; control) was purified whole‑genome analysis performed high‑density arrays. Shared unique copy number (CNA) were identified between...
Integrons are genetic elements that store, express and exchange gene cassettes. These characterized by containing a codes for an integrase (intI), cassette integration site (attI) variable region holding the Using bioinformatics molecular biology methods, functional integron found in Aeromonas sp. 3925, strain isolated from diarrheal stools, is described. To confirm class, phylogenetic analysis with amino acid sequences was conducted. The associated to class 4 integrases; however, it clearly...
Burkholderia sensu stricto is comprised mainly of opportunistic pathogens. This group widely distributed in the environment but especially important clinical settings. In Mexico, few species have been correctly identified among patients, most often B. cepacia described.
ABSTRACT Helicobacter pylori strains are the major risk factor for gastric cancer. Strains vary in their content of disease-associated genes, so genome-wide analysis cancer-isolated will help elucidate pathogenesis and genetic diversity. We present draft genome sequence H. isolated from a Mexican patient with intestinal
In this study we evaluate the capacity of Virtual Hybridization to identify between highly related bacterial strains. Eight genomic fingerprints were obtained by virtual hybridization for Bacillus anthracis genome set, and a set 15,264 13-nucleotide short probes designed produce unique each organism. The data from fingerprint used obtain patterns simulating DNA microarray. Two methods used: Direct Extended method number potential sites thus determine minimum sensitivity value discriminate...
Gastric (GC) and breast (BrC) cancer are two of the most common deadly tumours. Different lines evidence suggest a possible causative role viral infections for both GC BrC. Wide genome sequencing (WGS) technologies allow searching agents in tissues patients with cancer. These have already contributed to establish virus-cancer associations as well discovery new tumour viruses. The objective this study was document infection BrC Mexican patients. In order gain idea about cost effective...
ABSTRACT The synthesis of Indole Acetic Acid from tryptophan has been described in plants, fungi and bacteria; it is thus known as tryptophan-dependent indole acetic acid. Four possible pathways IAA formation have described, including the acetonitrile acid (IAN), acetamide (IAM), indole-pyruvic (IAP) tryptamine (TRM) pathways. Of these, pathway particularly important because when this compound transformed into IAA, a nitrogenated molecule released. microorganisms that are called nitrogen...
The Virtual Hybridization approach predicts the most probable hybridization sites across a target nucleic acid of known sequence, including both perfect and mismatched pairings.Potential sites, having user-defined minimum number bases that are paired with oligonucleotide probe, first identified.Then free energy values evaluated for each potential site, if it has calculated equal or higher negative value than cut-off value, is considered as site high probability hybridization.The Universal...