Abstract Background Postoperative cognitive dysfunction (POCD) is associated with worsened prognosis especially in aged population. Clinical and animal studies suggested that electroacupuncture (EA) could improve POCD. However, the underlying mechanisms EA’s regulatory role of inflammasomes remain unclear. Methods The model POCD was established by partial hepatectomy surgery 18‐month mice or without postoperative EA treatment to Baihui acupoint (GV20) for 7 days. Cognitive functions were...

Opioid preconditioning against ischemia reperfusion injury has been well studied in myocardial and neuronal tissues. The objective of this study was to determine whether remifentanil could attenuate hepatic investigate the mechanisms.A rat model a hepatocyte hypoxia reoxygenation (HR) were used, respectively, two series experiments. Remifentanil administered before or experiments repeated with previous administration naloxone, L-arginine N-ω-nitro-L-arginine methyl ester, nonselective opioid...

Background The study aimed to develop a risk prediction model through screening preoperative factors for acute kidney injury (AKI) after heart valve replacement in patients with normal renal function. Methods A total of 608 function who underwent from November 2013 June 2022 were analyzed retrospectively. Lasso regression was used preliminarily screen potential factors, which entered into the multivariable logistic analysis identify independent postoperative AKI. Based on results, developed,...

Objective This study aims to evaluate the effectiveness of transcutaneous auricular vagus nerve stimulation (taVNS) on postoperative pain in patients following perianal surgery.

To compare isoflurane anesthesia in patients with or without hyperbilirubinemia undergoing hepatobiliary surgery.Forty-two obstructive jaundice and 40 control normal liver function scheduled for surgery under were studied. Anesthesia was induced propofol (1.5-2 mg/kg) remifentanil (2 microg/kg). After tracheal intubation, titrated using oxygen-enriched air, adjusted to maintain a bispectral index (BIS) value of 46-54. Ephedrine, atropine used hemodynamic parameters within 30% the baseline....

Background Measuring pain on digital devices using classic unidimensional scales such as the visual analog scale (VAS), numerical rating (NRS), and faces (FPS) has been proven to be reliable valid. Emoji are pictographs designed in colorful form following Unicode standard. It could more beneficial use emoji of FPS because can easily fit most open-source so no approval would needed before use. With a concise user-friendly design, (Emoji-FPS) might generalizable wider population preferred by...

Abstract: Although the efficacy of transcatheter arterial chemoembolization (TACE) has been recommended as first-line therapy for nonsurgical patients with hepatocellular carcinoma (HCC), it is difficult to accurately predict TACE. Therefore, this study evaluated TACE HCC using magnetic resonance (MR) diffusion-weighted imaging (DWI). A total 84 who received initial were selected and assigned stable group (n=39) progressive (n=45). Before treatment, a contrast-enhanced MR scan DWI ( b =300,...

Electroacupuncture (EA) is reported to possess anti-inflammatory properties and has beneficial effects on acute respiratory distress syndrome (ARDS). However, the underlying mechanisms of EA ARDS remain unclear. This study aims investigate protective effect LPS-induced ARDS. In this study, Sprague-Dawley male rats were treated with at Hegu (LI4) for 45 minutes before LPS instillation (0.4 mg/kg, 100 ul). H&E staining, wet-to-dry weight (W/D) ratio, PaO2, protein content in BALF employed...

The evolution of pain after anorectal surgery has not been well characterized. main objective this study is to evaluate patterns in acute postoperative patients undergoing short-stay surgery. A total 217 were included the study, which used group-based trajectory modeling estimate and then examined relationships between sociodemographic or surgical factors trajectories. Three distinct trajectories determined: hemorrhoidectomy (OR, 0.15), higher anxiety 3.26), a preoperative behavior score...

Flavonoids have been shown to be beneficial in a variety of inflammatory and metabolic diseases because their anti-inflammatory antioxidant properties. However, previous epidemiological studies only demonstrated negative correlation between flavonoid intake on markers, the optimal dietary flavonoids subclasses terms efficacy remains undetermined. This study was based 3 cycles (2007-2010, 2017-2018) National Health Nutrition Examination Survey corresponding expanded database. Weighted...

Abstract The emergence of myelinating oligodendrocytes represents a pivotal developmental milestone in vertebrates, given their capacity to ensheath axons and facilitate the swift conduction action potentials. It is widely accepted that cortical oligodendrocyte progenitor cells (OPCs) arise from medial ganglionic eminence (MGE), lateral/caudal (LGE/CGE) radial glial (RGCs). Here, we used two different fate mapping strategies challenge established notion LGE generates OPCs. Furthermore,...

Our previous clinical trial showed that etomidate requirements to reach an appropriate level of anesthesia in patients with obstructive jaundice were reduced, which means these are more sensitive etomidate. However, the mechanism is still not completely clear. The present study was aimed investigate by bilirubin facilitates induced sedation. A bile duct ligation (BDL) rat model used simulate jaundice. Anesthesia sensitivity determined time loss righting reflex (LORR). Intrathecal injection...

Introduction Colonoscopy is currently the most commonly used and effective method for early detection, diagnosis treatment of tumours colon rectum. However, similar to other invasive procedures, it associated with adverse reactions such as pain abdominal distension. Electroacupuncture (EA) has been proposed a potential relieving this discomfort; however, there limited evidence supporting its efficacy. Therefore, aim study investigate effectiveness EA when prior colonoscopy. Methods analysis...

To investigate the mechanism of electroacupuncture (EA) in improving long-term survival rate mice after myocardial infarction by promoting angiogenesis and inhibiting ventricular remodeling.A total 102 male C57BL/6 were randomly divided into sham operation, model EA groups (n=34 /group). The was established permanent ligation anterior descending branch left coronary artery. Beginning from 3rd day ligation, (2 Hz/20 Hz) applied to bilateral "Neiguan" (PC6) "Ximen" (PC4) for 30 min, once a 28...

Stress ulcer (SU) is one of the main causes prolonged hospital stay, poor prognosis, and increased mortality in critically ill patients. This study aimed to investigate effect electroacupuncture (EA) on SU patients with severe neurological diseases explore its possible mechanisms. Taking adult neurocritical care as research object, they were randomly divided into EA group control group. Through perioperative intervention, following indicators documented: observation indicator (the effective...

<sec> <title>BACKGROUND</title> Measuring pain on digital devices using classic unidimensional scales such as the visual analog scale (VAS), numerical rating (NRS), and faces (FPS) has been proven to be reliable valid. Emoji are pictographs designed in colorful form following Unicode standard. It could more beneficial use emoji of FPS because can easily fit most open-source so no approval would needed before use. With a concise user-friendly design, (Emoji-FPS) might generalizable wider...

Abstract OBJECTIVE: The dense distribution of perianal nerves, having to defecate, and underappreciated analgesia make the postoperative pain anorectal surgery significantly serious. However, evolution after has not been well characterized. main objective is evaluate patterns in acute patients undergoing short-stay surgery.The surgery. Methods: study included 217 who underwent for hemorrhoids fistula. VAS scale was used record across days 1 through 10. primary analysis group-based trajectory...