A5032339855- Asthma and respiratory diseases
- Olfactory and Sensory Function Studies
- Allergic Rhinitis and Sensitization
- Sinusitis and nasal conditions
- Stress Responses and Cortisol
- Healthcare professionals’ stress and burnout
- Stress and Burnout Research
- Diet and metabolism studies
- Epigenetics and DNA Methylation
- Bone health and osteoporosis research
- Tryptophan and brain disorders
- Bone and Joint Diseases
- Cancer-related gene regulation
- Health and Well-being Studies
- IL-33, ST2, and ILC Pathways
- Hemoglobinopathies and Related Disorders
- Organ Transplantation Techniques and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Tendon Structure and Treatment
- Biochemical Analysis and Sensing Techniques
- Dermatology and Skin Diseases
- Otitis Media and Relapsing Polychondritis
- Schizophrenia research and treatment
- Nutritional Studies and Diet
Wuhan University
2020-2025
Renmin Hospital of Wuhan University
2020-2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2018-2024
Soochow University
2021-2024
Shandong University of Traditional Chinese Medicine
2022-2023
Jinan Central Hospital
2023
Northeast Agricultural University
2021
Tianjin Anding Hospital
2012-2020
Tianjin Medical University
2019-2020
Shenyang Agricultural University
2018
This study investigated the effects of oleanolic acid (OA) on hepatic lipid metabolism and gut–liver axis homeostasis in an obesity-related non-alcoholic fatty liver disease (NAFLD) nutritional animal model explored possible molecular mechanisms behind its effects. The results revealed that OA ameliorated development metabolic disorders, insulin resistance, steatosis obese rats. Meanwhile, restored high-fat-diet (HFD)-induced intestinal barrier dysfunction endotoxin-mediated induction...
A series of studies have suggested that teachers are likely to experience professional burnout in various regions around the world. To date, no known research has been conducted investigate prevalence and correlates among preschool China. This study examined level self-reported Chinese teachers.A cross-sectional was among1795 Tianjin, China, during August 2018-October 2018. The validated version 15-item Maslach Burnout Inventory used assess burnout. self-administered questionnaire collected...
Opioid preconditioning against ischemia reperfusion injury has been well studied in myocardial and neuronal tissues. The objective of this study was to determine whether remifentanil could attenuate hepatic investigate the mechanisms.A rat model a hepatocyte hypoxia reoxygenation (HR) were used, respectively, two series experiments. Remifentanil administered before or experiments repeated with previous administration naloxone, L-arginine N-ω-nitro-L-arginine methyl ester, nonselective opioid...
Glycolytic enzymes are known to play pivotal roles in cancer cell survival, yet their molecular mechanisms remain poorly understood. Phosphoglycerate mutase 1 (PGAM1) is an important glycolytic enzyme that coordinates glycolysis, pentose phosphate pathway, and serine biosynthesis cells. Herein, we report PGAM1 required for homologous recombination (HR) repair of DNA double-strand breaks (DSBs) caused by DNA-damaging agents. Mechanistically, facilitates DSB end resection regulating the...
The objective of this network meta‐analysis (NMA) was to assess the pain relief performance eight different plantar fasciitis therapies, including nonsteroidal anti‐inflammatory medications, corticosteroid injections (CSs), autologous whole blood, platelet‐rich plasma (PRP), extracorporeal shockwave therapy (ESWT), ultrasound (US), botulinum toxin A (BTX‐A), and dry needling (DN). Published prospective or randomized controlled trials (RCTs) as for above therapies were identified by searching...
ObjectiveTo investigate olfactory and gustatory dysfunction in patients with coronavirus disease 2019 (COVID-19) Wuhan using a telephone interview.MethodsThis retrospective survey investigated 196 consecutive COVID-19 at 3 months after discharge from two hospitals Wuhan, China. The characteristics of the patient's course time to recovery and/or (OD GD) were collected by interview. Demographic data patient medical records.ResultsA total completed study. most prevalent general symptoms fever,...
Abstract This study aimed to assess the correlation between serum albumin levels and coronary heart disease (CHD) risk in adults aged over 45 years. cross-sectional used non-institutionalized US population from National Health Nutrition Examination Survey (NHANES 2011–2018) as sample source. Multiple logistic regression was performed evaluate association CHD risk. Smooth curve fitting explore potential nonlinear relationships. When relationships were found, a recursive algorithm calculate...
Chronic rhinosinusitis with nasal polyps (CRSwNP) can be classified into eosinophilic CRSwNP (eCRSwNP) and non-eosinophilic (non-eCRSwNP) by tissue biopsy, which is difficult to perform preoperatively. Clinical biomarkers have predictive value for the classification of CRSwNP. We aimed evaluate application artificial neural network (ANN) modeling in distinguishing different endotypes based on clinical biomarkers.Clinical parameters were collected from 109 patients, their ability was...
Abstract Background Activation of heme oxygenase-1 (HO-1) has been proved to reduce damages the liver in ischemia reperfusion injury. The objective present study was determine whether clinic relevant doses isoflurane treatment could be sufficient activate HO-1 inducing, which confers protective effect against hepatic ischemia-reperfusion Methods artery and portal vein left median lobes forty male Sprague-Dawley rats were occluded for 60 minutes. Reperfusion allowed 4 hours before animal...
Allergic rhinitis (AR) is an inflammatory disorder of the nose caused by immunoglobulin E (IgE)-mediated immune response to allergens. Apart from typical symptoms sneezing, itching, rhinorrhea, and nasal congestion, behavioral complications were also reported be associated with progression AR, such as cognitive deficits, mood changes, memory decline, attention deficiency, poor school performance, anxiety, depression. Recent human studies have suggested that alterations in brain function...
Allergic rhinitis (AR) is a common otolaryngology disease and one of the clinical causes olfactory dysfunction (OD). The bulb serves as transfer station for information transmission, alleviating its neuroinflammation may be expected to improve AR-induced OD. Recent studies have suggested that dopamine D2 receptor acts key target in regulating immune functions neuroinflammatory reaction. However, effect on still unknown.
The present study aimed to investigate whether microRNA (miR)‑31 exerted therapeutic potential in allergic rhinitis (AR) and explore its underlying mechanism. Firstly, the expression levels of miR‑31 were detected by reverse transcription‑quantitative PCR nasal mucosa patients mice. Subsequently, an ovalbumin (OVA)‑induced animal model AR was constructed. Allergic symptom score, histopathological characteristics, OVA‑specific immunoglobulin E (IgE) titers,...
Background With the popularization of Internet and medical knowledge, more people are learning about allergic rhinitis (AR) on Internet. Objective This study aims to analyze epidemiological characteristics online public attention AR in Wuhan, China, utilizing most popular search engine mainland China meteorological data Wuhan. Methods To volume (SV) “Allergic Rhinitis” Mandarin AR-related terms from 1 January 2014 through 31 December 2021 were recorded. For user interest, demand collected...