- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Frailty in Older Adults
- Body Composition Measurement Techniques
- Obesity, Physical Activity, Diet
- Vitamin D Research Studies
- Diet and metabolism studies
- Dental Health and Care Utilization
- Cancer Risks and Factors
- Bone health and osteoporosis research
- Global Cancer Incidence and Screening
- Obesity and Health Practices
- Oral microbiology and periodontitis research
- Eating Disorders and Behaviors
- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Iron Metabolism and Disorders
- Clinical Nutrition and Gastroenterology
- Vitamin C and Antioxidants Research
- Cerebral Palsy and Movement Disorders
- Dementia and Cognitive Impairment Research
- Health Promotion and Cardiovascular Prevention
- Hemoglobinopathies and Related Disorders
- Hormonal and reproductive studies
- Dental Erosion and Treatment
Concord Repatriation General Hospital
2014-2024
The University of Sydney
2015-2024
Anzac Research Institute
2016-2024
UNSW Sydney
2015-2024
Concord Hospital
2013-2019
Harry Perkins Institute of Medical Research
2016
Australian Research Council
2015
Sydney Hospital
2014-2015
Faculty of Public Health
2013-2015
University College London
2005-2013
Summary To monitor the health of public in England, UK, Central Health Monitoring Unit within UK Department commissioned an annual examination survey, which became known as Survey for England (HSE). The first survey was completed 1991. HSE covers all and is a nationally representative sample those residing at private residential addresses. Each year consists new addresses people. collects detailed information on mental physical health, health-related behaviour, objective biological measures...
to explore the longitudinal associations between body composition measures, sarcopenic obesity and outcomes of frailty, activities daily living (ADL) instrumental ADL (IADL) disability, institutionalisation mortality. men aged ≥ 70 years (2005–07) from Concord Health Ageing in Men Project were assessed at baseline (n = 1,705), 2 1,366) 5 954). The main outcome measures frailty (adapted Fried criteria), ADL, including personal care mobility IADL disability (ability perform tasks for...
Analyses performed by the Sarcopenia Definitions and Outcomes Consortium (SDOC) identified cut-points in several metrics of grip strength for consideration a definition sarcopenia. We describe associations between SDOC-identified low (absolute or standardized to body size/composition); dual-energy x-ray absorptiometry (DXA) lean mass as previously defined literature (appendicular [ALM]/ht2 ); slowness (walking speed <.8 m/s) with subsequent adverse outcomes (falls, hip fractures, mobility...
ABSTRACT Body composition and muscle function have important implications for falls fractures in older adults. We aimed to investigate longitudinal associations between sarcopenic obesity its components with bone mineral density (BMD) incident Australian community-dwelling men. A total of 1486 men aged ≥70 years from the Concord Health Ageing Men Project (CHAMP) study were assessed at baseline (2005–2007), 2-year follow-up (2007–2009; n = 1238), 5-year (2010–2013; 861). At all three time...
To investigate the association between vitamin D deficiency and depressive symptoms in a national community sample of older people. Vitamin is common people with potential effects on mood.Data were analyzed from 2070 participants aged ≥65 years who had participated 2005 Health Survey for England. Serum 25-hydroxy (25(OH)D) levels (Geriatric Depression Scale) been measured. Covariates included age, sex, social class, season examination, physical health status.Depressive associated clinical...
Abstract Background Lack of consensus on how to diagnose sarcopenia has limited the ability this condition and hindered drug development. The Sarcopenia Definitions Outcomes Consortium (SDOC) was formed develop evidence-based diagnostic cut points for lean mass and/or muscle strength that identify people at increased risk mobility disability. We describe here proceedings a meeting SDOC other experts discuss strategic considerations in development definition. Methods Presentations panel...
Comorbidity and multimorbidity are common in older people. Here we used a novel analytic approach called Association Rules together with network analysis to evaluate (two or more disorders) comorbidity old age. A population-based cross-sectional study was undertaken where 17 morbidities were analyzed using analysis, cluster methodology. interestingness score developed quantify the richness variability of comorbidities associated an index condition. The participants community-dwelling men...
The potential for older adults with obesity to also have sarcopenia, and the health consequences of 'sarcopenic obesity', may be underappreciated by professionals. primary aim this secondary analysis a prospective cohort study men was explore prevalence functional outcomes sarcopenic based on different consensus definitions.1416 community-dwelling aged ≥70 years were classified into sarcopenia categories according European Working Group Sarcopenia in Older People (EWGSOP2) definition,...
Background: vitamin D deficiency among older people results in poor bone and muscle health an increased risk of fractures. In the UK, government initiatives launch Osteoporosis Strategy have been place since 1998, highlighting importance adequate levels for its prevention. The aim this analysis is to assess status examine associations with factors England.
The aim of the present study was to investigate relationships physical activity types and sedentary behaviour with BMI waist circumference (WC). sample comprised 6215 adults (2775 men, 3440 women) aged 16 years over living in Scotland. Self-reported moderate vigorous intensity (MVIA) included domestic activity, walking, sports exercises. MVIA levels were classified as being inactive, insufficiently active, sufficiently active for general health benefits obesity prevention. Sedentary time...
Objective To investigate the association between iron deficiency status and depressive symptoms in a national community sample of older people. Methods Cross-sectional data were analyzed from 1875 participants 65 years who had participated 2005 Health Survey for England. Serum hemoglobin (Hb), ferritin, transferrin receptor levels (Geriatric Depression Scale) been measured. Covariates included age, sex, occupation, multivitamin intake, smoking status, body mass index, hypertension, heart...
The objective of this study is to examine associations between Hb levels and sarcopenia, low muscle strength, functional measures, activities daily living (ADL) instrumental ADL (IADL) disabilities in older Australian men. Men aged 70 years (2005–2007) from the Concord Health Ageing Project were assessed at baseline (n = 1,705), 2 1,367), 5 958). main outcome measurements walking speed, IADL disabilities, sarcopenia using Foundation for National Institutes criteria (low appendicular lean...
Poor vitamin D status and frailty are common in older people associated with adverse health outcomes. The aim of this study was to examine the associations between serum 25-hydroxyvitamin 1,25-dihydroxyvitamin levels components Australian men. Cross-sectional analysis Concord Health Ageing Men Project, a large epidemiological conducted Sydney, Australia, January 2005 May 2007. Participants included 1,659 community-dwelling Main outcome measurements were (assessed using Cardiovascular Study),...
It is unclear whether older men with osteopenia/osteoporosis and sarcopenia (so-called osteosarcopenia) are at greater risk of falls fractures than those either condition alone. One thousand five hundred seventy-five community-dwelling aged ≥70 years had appendicular lean mass, total hip lumbar spine bone mineral density determined by dual-energy x-ray absorptiometry, completed hand grip strength gait speed tests. Osteopenia/osteoporosis was defined as a T-score any site ≤−1.0 SD. Sarcopenia...
Recent evidence suggests that low vitamin D concentrations are associated with increased levels of inflammatory markers. However, there limited studies investigating associations between and markers in the general population much this older adults is inconclusive. Therefore, study investigates cross-sectional association serum 25-hydroxyvitamin (25(OH)D) 5870 English from wave 6 (2012-2013) Longitudinal Study Ageing (ELSA). ELSA a large prospective observational community-dwelling people...
To explore the associations between serum 25-hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin (1,25D) levels at baseline incidence of sarcopenia over time in older Australian community-dwelling men. Of 1,705 men aged ≥70 years (2005–2007) participating Concord Health Ageing Men Project, those without (n = 1,312 for 25D n 1,231 1,25D), 2 1,024 956 5-year follow-up 709 663 1,25D) were included study. The main outcome measurement was defined as appendicular lean mass adjusted body index <0.789...
BACKGROUND The Sarcopenia Definitions and Outcomes Consortium (SDOC) sought to identify cut points for muscle strength body composition measures derived from dual‐energy x‐ray absorptiometry (DXA) that discriminate older adults with slow walking speed. This article presents the core analyses used guide SDOC position statements. DESIGN Cross‐sectional data of pooled data. SETTING University‐based research assessment centers. PARTICIPANTS Community‐dwelling men (n = 13,652) women: 5,115)...
To look at trends in generalised (body mass index (BMI) >or=30 kg m(-2)) and abdominal (waist circumference (WC) >102 cm men, >88 women) obesity among adults between 1993 2003, to evaluate their association with diabetes, hypertension hypertension-diabetes co-morbidity (HDC) England.Analyses of nationally representative cross-sectional population surveys, the Health Survey for England (HSE).Non-institutionalised men women aged >or=35 years.Interviewer-administered questionnaire...
OBJECTIVES: To investigate the association between dental health and cognitive impairment to examine extent which status accounts for low body mass index (BMI) in a national survey sample. DESIGN: A secondary analysis of data from Health Survey England 2000. SETTING: nationally representative cross‐sectional population survey. PARTICIPANTS: Two thousand four hundred sixty‐three adults aged 65 older living private households 1,569 care homes. MEASUREMENTS: Data collected by interview...
the importance of vitamin D for bone health is well known, but emerging evidence also suggests that adequate status may be protective against non-communicable diseases. In UK, government initiatives highlighting among older people have been in place since 1998.the aim this analysis to assess aged > or =65, living private households England, 2005 and make comparisons with Health Survey England (HSE) 2000 National Diet Nutrition (NDNS), 1994. We examine associations hypovitaminosis [serum...