A5102024742- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Folate and B Vitamins Research
- Celiac Disease Research and Management
- Bone and Joint Diseases
- Pregnancy and preeclampsia studies
- Microscopic Colitis
- Plant Reproductive Biology
- Pharmacological Effects and Toxicity Studies
- Fecal contamination and water quality
- Carbohydrate Chemistry and Synthesis
- Glycogen Storage Diseases and Myoclonus
- Gastrointestinal disorders and treatments
- Metabolism and Genetic Disorders
- Photosynthetic Processes and Mechanisms
- Food Allergy and Anaphylaxis Research
- Neurological and metabolic disorders
- Plant Molecular Biology Research
- Parasites and Host Interactions
- Child Nutrition and Water Access
- Helicobacter pylori-related gastroenterology studies
- Allergic Rhinitis and Sensitization
- Lysosomal Storage Disorders Research
- Viral gastroenteritis research and epidemiology
- Blood groups and transfusion
Universidade Federal da Bahia
2008-2023
Complexo Hospitalar Universitário Professor Edgard Santos
2012-2022
Fundação Oswaldo Cruz
2016
Hospital Ana Nery
2013
Diarrhea remains a major health issue in developing countries, with high morbidity and mortality rates. Determining the incidence of acute diarrhea children its associated factors is crucial to planning preventive approaches. The objective this study was determine assess some relevant it younger than 40 months living two slums Salvador, Brazil. This first prospective cohort, community-based that performed periurban Eighty-four were randomly selected visited every other day for one year....
Niemann-Pick Disease Type C (NPC) is an inherited, often fatal neurovisceral lysosomal storage disease characterized by cholesterol accumulation in every cell with few known treatments. Defects transport cause sequestration of unesterified within the endolysosomal system. The discovery that systemic administration hydroxypropyl-beta cyclodextrin (HPβPD) to NPC mice could release trapped from lysosomes, normalize levels liver, and prolong life, led expanded access use patients. HPβCD has been...
ContextNeurological symptoms have been well-documented in patients with celiac disease, nevertheless, the presumption of a greater prevalence epilepsy remains controversial.ObjectivesTo determine frequency disease children and adolescents idiopathic or cryptogenic epilepsy.MethodsA cross-sectional study. One hundred pediatric non-symptomatic were followed-up at two public neurology clinics Salvador, Bahia, Brazil. Screening for was performed by serial measurements IgA anti-transglutaminase...
Abstract Background: Stroke is a severe clinical disorder in sickle cell disease (SCD), and few studies have evaluated transcranial Doppler (TCD) flow velocities hemoglobin SC (HbSC). The guidelines for stroke risk are based on evaluations anemia (SCA) or HbS/β thalassemia. Procedure: In this study, we compare cerebral blood patients with SCD stratified by genotypes. A total of 1,664 pediatric underwent TCD velocity screening, the time‐averaged maximum mean (TAMM) was determined middle...
Individuals with sickle cell anemia may suffer symptomatic or silent cerebral infarcts leading to neurocognitive complications. This study investigated the cognitive and intellectual performance of children adolescents anemia.The socioeconomic status, clinical aspects behavioral profile 15 young individuals were evaluated. The Wechsler Intelligence Scale for Children, Developmental Neuropsychological Assessment Test, Child Behavior Checklist applied.Participants a history stroke had lower...
Reference values for cerebral blood flow velocity (CBFV) in hemoglobin SC disease (HbSC) have not been established. We aimed to investigate associations between laboratory and genetic biomarkers associated with CBFV HbSC children. Sixty-eight children were included; was analyzed by transcranial Doppler, the time-averaged maximum mean (TAMMV) estimated. Hematological, biochemical, immunological, analyses performed. TAMMV negatively correlated red cell count (RBC) count, hemoglobin,...
Stroke is one of the highest complications sickle-cell anemia (SCA). The Transcranial Doppler (TCD) has been adopted worldwide as a gold standard method for detecting alterations in blood velocity cerebral arteries. In this study, we investigated association between laboratory parameters and increased flow Brazilian SCA pediatric patients.The study included 159 patients with SCA, submitted to TCD screening, time-averaged maximum mean (TAMMV) was determined middle artery (MCA), anterior...
(1) Background: Modification of the structural elements allergens is widely used in field allergies. The goal present research was to express, purify, and characterize shortened recombinant group 5 allergen Dermatophagoides pteronyssinus (rDer p 5). (2) Methods: rDer storage stability aggregation capacity were explored through silico analysis, dynamic light scattering (DLS), SDS-PAGE. Serum IgE reactivity cytokine amount investigated sera or cell culture supernatants ELISA, MULTIPLEX®,...