A5103122617- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Neonatal Respiratory Health Research
- Sleep and related disorders
- Dysphagia Assessment and Management
- Pleural and Pulmonary Diseases
- Cancer Cells and Metastasis
- Lymphatic System and Diseases
- Developmental and Educational Neuropsychology
- Respiratory Support and Mechanisms
- Intramuscular injections and effects
- Circadian rhythm and melatonin
- Airway Management and Intubation Techniques
- Skin Protection and Aging
- Actinomycetales infections and treatment
- Olfactory and Sensory Function Studies
- Tuberculosis Research and Epidemiology
- Biliary and Gastrointestinal Fistulas
- Medication Adherence and Compliance
- Infectious Diseases and Mycology
- Infective Endocarditis Diagnosis and Management
- Water Treatment and Disinfection
- Infant Development and Preterm Care
Hospital Universitari Sant Joan D'Alacant
2006-2025
Bellvitge University Hospital
2018
Hospital Universitario de Guadalajara
2018
Hospital General Universitario de Alicante Doctor Balmis
2014
Hospital de Sant Pau
1992
We hypothesized that obstructive sleep apnea (OSA) can predispose individuals to lower airway infections and community-acquired pneumonia (CAP) due upper microaspiration. This study evaluated the association between OSA CAP.We performed a case-control included 82 patients with CAP 41 other (control group). The controls were matched according age, sex body mass index (BMI). A respiratory polygraph (RP) was upon admission for in both groups. severity of assessed Pneumonia Severity Index (PSI)....
The efficacy of continuous positive airway pressure (CPAP) treatment in elderly patients with nonsevere obstructive sleep apnoea (OSA) is controversial. objective this study was to assess the effect CPAP moderate OSA terms clinical, quality-of-life and neurocognitive measures. This an open-label, randomised, multicentre clinical trial 145 (≥70 years old) confirmed (apnoea–hypopnoea index 15–29.9 events·h −1 ) randomised receive (n=73) or no (n=72) for 3 months. primary end-point Epworth...
The aim of this study to evaluate the efficacy a home-based programme on clinical response, continuous positive airway pressure (CPAP) compliance and cost in population high pre-test probability suffering obstructive sleep apnoea syndrome (OSAS). Patients were randomised into following three groups. Group A: home respiratory polygraphy (RP) follow-up; group B: hospital polysomnography C: RP follow-up. Evaluation during 6 months included Epworth Sleepiness Scale (ESS), Functional Outcomes...
The utility of home respiratory polygraphy (HRP) was assessed as an alternative to polysomnography (PSG) in the diagnosis childhood obstructive sleep apnea syndrome (OSAS). PSG indicated only patients with concomitant disease or where HRP results were questionable. follow-up period 1 year. We recorded clinical and anthropometric data, physical examination findings, variables, severity level choice therapy. 121 children, 70 boys 51 girls, mean age 7 ± 4 years, body mass index (BMI) 19 5...
Background/Objectives: To translate the OSD-6 questionnaire (6-item quality of life for children with obstructive sleep disorders) to Spanish and analyze reliability validity version. Methods: We included apnea (OSA). All underwent polysomnography before after adenotonsillectomy. Study variables age, sex, symptoms, values, body measurements, Mallampati Brodsky classification. Parents or caregivers completed at baseline 3 6 months Following translation back-translation instrument, we...
Background/Objectives: To translate the OSD-6 questionnaire (6-item quality of life for children with obstructive sleep disorders) into Spanish and to assess its psychometric properties clinical usefulness. Methods: We included apnea (OSA). All underwent polysomnography before after adenotonsillectomy. Study variables age, sex, symptoms, values, body measurements, Mallampati Brodsky classification. Parents or caregivers completed at baseline 3 6 months Following translation back-translation...
To compare the clinical and polysomnographic features of obstructive sleep apnea (OSA) in children with adenotonsillar hypertrophy (Group A) comorbidities B). A five-year prospective study using nocturnal polysomnography before after treatment. We included 168 patients: 121 Group 47 B, differences age (6.5 ± 3 vs. 8.6 4 years; p < 0.001), body mass index (BMI) (18 20 7 kg/m2; 0.05), neck circumference (28 30 5 cm; obesity (17% 30%; 0.05). B patients were more likely to have facial anomalies...
Midkine (MDK) might mediate the proangiogenic effect of intermittent hypoxia (IH) in patients with obstructive sleep apnea (OSA) and cutaneous melanoma (CM). We compare circulating MDK CM without OSA, their relationship tumor aggressiveness, while exploring vitro effects soluble on human lymphatic endothelial (HLEC) cell proliferation. In 360 patients, studies serum level measurements were performed. The proliferation was assessed using HLEC lines patient sera under both normoxia IH. levels...
In patients with obstructive sleep apnoea (OSA), intermittent hypoxia induces overexpression of paraspeckle component (PSPC)1, a master modulator transforming growth factor (TGF)-β signalling, which promotes cell cancer progression through epithelial-mesenchymal transition (EMT) and acquisition stem (CSC)-like features. However, the persistence hypoxia-induced effects on PSPC1, their consequences in are not known. To this effect, circulating PSPC1 levels were compared cutaneous melanoma or...
Abstract Active transforming growth factor-β1 (TGF-β1), a cytokine partially regulated by hypoxia and obesity, has been related with poor prognosis in several tumors. We determine whether obstructive sleep apnea (OSA) increases serum levels of active TGF-β1 patients cutaneous melanoma (CM), assess their relationship aggressiveness analyze the factors to obese non-obese OSA patients. In multicenter observational study, 290 CM were underwent studies. was increased moderate-severe vs. non-OSA...