Yan Zhang

ORCID: 0000-0003-0551-4222
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Research Areas
  • Heat shock proteins research
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • Plant biochemistry and biosynthesis
  • Virus-based gene therapy research
  • Physiological and biochemical adaptations
  • Meat and Animal Product Quality
  • Plant Gene Expression Analysis
  • Ruminant Nutrition and Digestive Physiology
  • Reproductive Physiology in Livestock
  • Genetic and phenotypic traits in livestock
  • thermodynamics and calorimetric analyses
  • Plant Stress Responses and Tolerance
  • Viral Infections and Immunology Research
  • Postharvest Quality and Shelf Life Management
  • Phytochemicals and Antioxidant Activities
  • RNA modifications and cancer
  • Gut microbiota and health
  • Exercise and Physiological Responses
  • Advanced Chemical Sensor Technologies
  • Endoplasmic Reticulum Stress and Disease
  • Transgenic Plants and Applications
  • Invertebrate Immune Response Mechanisms
  • Seed Germination and Physiology
  • Genetic Syndromes and Imprinting

Henan Agricultural University
2019-2024

Henan University
2019-2024

Hainan Provincial Academy of Agricultural Sciences
2023

Chinese Academy of Agricultural Sciences
2022

Institute of Plant Protection
2022

Beijing University of Agriculture
2022

Beibu Gulf University
2022

Neijiang Normal University
2022

Qingdao University
2020

Affiliated Hospital of Qingdao University
2020

Abstract YTH Domain Containing 1 (YTHDC1) is one of the m 6 A readers that essential for oocyte development and tumor progression. The role YTHDC1 in neuronal survival ischemic stroke unknown. Here, we found was unregulated early phase stroke. Knockdown exacerbated brain injury overexpression protected rats against injury. Mechanistically, promoted PTEN mRNA degradation to increase Akt phosphorylation, thus facilitating particular after ischemia. These data identify as a novel regulator...

10.1038/s41419-020-03186-2 article EN cc-by Cell Death and Disease 2020-11-13

Catalases (CATs) are present in almost all living organisms and play important roles plant development response to various stresses. However, there is relatively little information on CAT genes wheat related Triticeae species. A few studies family have been reported. In this study, ten proteins (TaCATs) were identified classified into three groups based their phylogenetic features sequence analysis. The analysis of the structure motif composition TaCAT suggested that a segmental duplication...

10.3390/ijms23010542 article EN International Journal of Molecular Sciences 2022-01-04

Abstract Mammalian ocular lens development results via a differentiation program that is highly regulated by tissue‐specific transcription factors. Central to this the terminal of fiber cells, which develop from epithelial cells on anterior surface lens, accompanied change in cell shape and expression structural proteins (such as membrane MP19, MIP26, connexin 43, 46, 50, cytoskeletal CP49, CP115, α, β, γ crystallins), creating transparent, refractive index gradient lens. Mutations genes...

10.1002/gene.20087 article EN genesis 2004-12-01

The heat shock transcription factors (HSFs) family is widely present in eukaryotes including plants. Recent studies have indicated that HSF a multifunctional group of genes involved plant growth and development, as well response to abiotic stresses. Here we combined the bioinformatic, molecular biology way dissect function Hsf, specifically HsfB4 wheat under In this study, identified 78 TaHSF (Triticum aestivum) analyzed their phylogenetic relationship expression regulation motifs. Next,...

10.3389/fpls.2022.1047400 article EN cc-by Frontiers in Plant Science 2023-01-25

Heat shock factors (Hsfs) play pivotal roles in plant stress responses and confer tolerance. However, the functions of several Hsfs rice (Oryza sativa L.) are not yet known. In this study, genome-wide analysis Hsf gene family was performed. A total 25 OsHsf genes were identified, which could be clearly clustered into three major groups, A, B, C, based on characteristics sequences. Bioinformatics showed that tandem duplication fragment replication two important driving forces process...

10.3390/ijms231810830 article EN International Journal of Molecular Sciences 2022-09-16

Alfalfa hay is a commonly used and important feed ingredient in dairy production. To better expand the alfalfa supply market, it of great significance to explore impact from different sources on cow production performance. This study compared effects imported America (AAH) Spain (SAH) lactation performance rumen microbiota cows. Three hundred sixty healthy mid-lactation Holstein cows with similar body weight, milk yield, parity were randomly divided into two groups fed diets based AAH or SAH...

10.3389/fvets.2024.1433876 article EN cc-by Frontiers in Veterinary Science 2024-10-21

Small heat shock proteins (HSP20s) are a significant factor in plant growth and development response to abiotic stress. In this study, we investigated the role of HSP20s’ stress Sorbus pohuashanensis introduced into low-altitude areas. The HSP20 gene family was identified based on genome-wide data S. pohuashanensis, expression patterns tissue specificity stresses were evaluated. Finally, 38 genes that distributed 16 chromosomes. Phylogenetic analysis HSP20s showed closest genetic...

10.3390/genes13122241 article EN Genes 2022-11-29

Heat shock proteins (Hsps) function as molecular chaperones that enable organisms to withstand stress and maintain normal life activities. In this study, we identified heat protein 70 (encoded by hsp70), which exhibits a higher expression in the mature male testis than unmature of Ophraella communa. Tissue profile revealed Ochsp70 levels males were highest testis, whereas those females head. Moreover, was found be significantly induced female bursa copulatrix after mating. Double-stranded...

10.3389/fmolb.2022.931525 article EN cc-by Frontiers in Molecular Biosciences 2022-09-20

Roughage quality is a crucial factor influencing the growth performance and feeding cost of ruminants; however, systematic investigation mechanisms underlying this still lacking. In study, we examined performance, meat quality, ruminal fermentation parameters, rumen microbiome, tissue methylomes post-weaned Hu sheep fed low- or high-quality forage-based diets. Our results showed that in alfalfa hay (AG) peanut vine (PG) groups exhibited better slaughter than wheat straw group (WG). The AG...

10.3389/frmbi.2023.1272625 article EN cc-by Frontiers in Microbiomes 2024-01-03

10.1016/j.bbrc.2016.09.056 article EN Biochemical and Biophysical Research Communications 2016-09-15

Abstract Background Goat products have played a crucial role in meeting the dietary demands of people since Neolithic era, giving rise to multitude goat breeds globally with varying characteristics and meat qualities. The primary objective this study is pinpoint pivotal genes their functions responsible for regulating muscle fiber growth longissimus dorsi (LDM) through DNA methylation modifications Hainan black goats hybrid goats. Methods Whole-genome bisulfite sequencing (WGBS) was employed...

10.1186/s12863-023-01182-x article EN cc-by BMC Genomic Data 2023-12-14

Abstract Background Heterogeneous nuclear ribonucleoprotein (HnRNP) F is a member of HnRNP family proteins that participate in splicing cellular newly synthesized mRNAs by specifically recognizing tandem guanine-tracts (G-tracts) RNA sequences. Whether could recognize viral-derived G-tracts and affect virus replication remain poorly defined. Methods The effect on porcine reproductive respiratory syndrome (PRRSV) propagation was evaluated real-time PCR, western blotting, plaque-forming unit...

10.1186/s12985-022-01811-4 article EN cc-by Virology Journal 2022-05-15

Abstract Nitrogen is a major driving force for the improvement of crop yield worldwide but brings detrimental effects on ecosystems. Therefore, enhancing nitrogen use efficiency (NUE) vital sustainable agriculture. The nitrate transporter (NRT1/NPF) family associated with uptake and utilization indispensable to NUE in crops. As an important food security crop, cassava ( Manihot esculenta ) produces acceptable nutrient‐deficient soil. Here, we identified systematically analyzed NPF gene...

10.1002/csc2.21138 article EN Crop Science 2023-10-31

Mechanical damage and bacterial contamination of fresh cut flowers after harvesting can negatively affect the quality longevity flowers. In this study, effect different concentrations bactericide ClO2 (0, 0.025, 0.05, 0.075, 0.1 g·L-1) on Paeonia suffruticosa ‘Luoyang Hong’ was investigated. All treatments except for 0.025 g·L-1 treatment increased water uptake, membrane stability indices, activity antioxidant enzymes such as superoxide dismutase peroxidase, inhibited stem-end growth in...

10.2139/ssrn.4504085 preprint EN 2023-01-01

Highlights● A comprehensive analysis of the Hsf gene family in rice was performed, and duplication fragment replication events were two driving factors during OsHsf evolution expansion.● Two genes, OsHsfB4b OsHsfB4d, strongly response to drought stress.● The protein located nucleus OsHsfB4d both cytoplasm.● Over-expression Arabidopsis remarkably improved resistance.

10.2139/ssrn.4157606 article EN SSRN Electronic Journal 2022-01-01

Heat shock proteins (HSPs) are molecular chaperone that can help maintain cellular protein homeostasis, assist in correcting the folding of proteins, and protect organisms from stress when body is under conditions such as temperature changes or bacterial infections. In this study, HSP10 HSP40 genes Eriocheir hepuensis were cloned named Eh-HSP10 Eh-HSP40. The results show coding sequence length E. was 309 bp 1191 bp, encoding 102 396 amino acids, respectively. domain prediction has a Cpn10...

10.3390/fishes7060372 article EN cc-by Fishes 2022-12-05
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