Lüjun Chen

ORCID: 0000-0003-0671-5683
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About
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Research Areas
  • Wastewater Treatment and Nitrogen Removal
  • Water Quality Monitoring and Analysis
  • Pharmaceutical and Antibiotic Environmental Impacts
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Cancer-related molecular mechanisms research
  • Cancer Immunotherapy and Biomarkers
  • Microbial Fuel Cells and Bioremediation
  • Immunotherapy and Immune Responses
  • Cancer Research and Treatments
  • Membrane Separation Technologies
  • Peptidase Inhibition and Analysis
  • Water Quality Monitoring Technologies
  • Protease and Inhibitor Mechanisms
  • COVID-19 and healthcare impacts
  • Lung Cancer Treatments and Mutations
  • bioluminescence and chemiluminescence research
  • Circular RNAs in diseases
  • Algal biology and biofuel production
  • SARS-CoV-2 and COVID-19 Research
  • Cancer Genomics and Diagnostics
  • Immune Cell Function and Interaction
  • Water Quality and Pollution Assessment
  • Cancer, Hypoxia, and Metabolism
  • interferon and immune responses

First Affiliated Hospital of Gannan Medical University
2025

Tsinghua University
2014-2024

Affiliated Hospital of Guangdong Medical College Hospital
2022-2024

China Medical University
2023-2024

General Hospital of Shenyang Military Region
2023-2024

Soochow University
2014-2023

Guangdong Medical College
2022-2023

First Hospital of China Medical University
2023

Shanghai Normal University
2019

The First People's Hospital of Changzhou
2014

Cell-associated ARGs in wastewater treatment plants (WWTPs) has been concerned, however, cell-free WWTPs was rarely studied. In this study, the abundances of four representative ARGs, sulII, tetC, blaPSE-1, and ermB, a large municipal WWTP were investigated both cell-associated fractions. dominant fraction raw wastewater. After biological treatment, sludge settling, membrane filtration, disinfection, substantially reduced, though ratios ARG/16S rRNA gene increased with disinfection....

10.1021/acs.est.7b04283 article EN Environmental Science & Technology 2017-11-28

Abstract Background Circulating tumor cells (CTCs) hold immense promise in guiding treatment strategies for advanced gastric cancer (GC). However, their clinical impact has been limited due to challenges identifying epithelial-mesenchymal transition (EMT)-CTCs using conventional methods. Methods To bridge this knowledge gap, we established a detection platform CTCs based on the distinctive biomarker cell surface vimentin (CSV). A prospective study involving 127 GC patients was conducted,...

10.1186/s13046-024-03043-6 article EN cc-by Journal of Experimental & Clinical Cancer Research 2024-04-30

Abstract Hepatic leukemia factor (HLF) is aberrantly expressed in human malignancies. However, the role of HLF regulation ovarian cancer (OC) remains unknown. Herein, we reported that expression was upregulated OC tissues and stem cells (CSCs). Functional studies have revealed regulates cell stemness, proliferation, metastasis. Mechanistically, transcriptionally activated Yes-associated protein 1 (YAP1) subsequently modulated Hippo signaling pathway. Moreover, found miR-520e directly...

10.1038/s41419-023-06076-5 article EN cc-by Cell Death and Disease 2023-09-14

Obesity is a major health problem associated with Type 2 diabetes, non-alcohol fatty liver disease (NAFLD), and atherosclerosis. Functional lactic acid bacteria-fermented products have been reported to potential anti-obese effect. The present results revealed that Leuconostoc mesenteroides 4 (LMSS4)-fermented lemon peel filtrate slowed down the increase of body weight, decreased epididymal fat indices; it also serum levels TC (total cholesterol), TG (triglyceride), LDL-C (low-density...

10.1002/fsn3.70039 article EN cc-by Food Science & Nutrition 2025-02-01

Reliable and accurate oxygen-input control, which is critical to maintaining efficient nitrogen removal performance for partial nitritation-anammox (PN-A) process, remains one of the main operational difficulties. In this study, a novel, yet simple system (a process autotrophic nitrogen-removal, SPAN) with precise control was developed treat ammonium-rich wastewater via PN-A process. SPAN brings oxygen biomass by circulating water creating spray (shower) at water-air interface, effectively...

10.1016/j.watres.2020.116213 article EN cc-by Water Research 2020-07-20

Abstract Background It has been well documented that apolipoprotein M (apoM) is principally expressed in the liver and kidney. However we found there was weak apoM expression other tissues or organs too, which could not be ignored. In present study, therefore examined human colorectal including cancer tissues, adjacent normal polyp mucosa as inflammatory mucosa. Methods Tissue samples were collected from patients who underwent surgical resection endoscopic examination. ApoM mRNA levels...

10.1186/1476-511x-9-102 article EN cc-by Lipids in Health and Disease 2010-09-16

The potential biotoxicity to the environment should be addressed during wastewater treatment. In this study, of coking effluent from MBR, Fenton, electro-Fenton and coagulation treatment processes was evaluated using embryos larvae Japanese medaka (Oryzias latipes). acute toxicity based on 96-h larval mortality as well chronic embryo hatching, swim-up failure, growth, sexual ratio were determined. results showed that different have various levels. Fenton effluents much higher than MBR...

10.1039/c3em00064h article EN Environmental Science Processes & Impacts 2013-01-01

An Arthrospira platensis strain ZJWST-S1 was isolated in Jiaxing City, China, which proved able to proliferate quickly undiluted digested piggery wastewater (DPW), and the protein content algal biomass high. Single factor experiments showed that grow a Zarrouk medium as dosage of sodium bicarbonate, nitrate-nitrogen phosphate-phosphorus not less than 4.0 mg·L–1, 40 mg·L–1 10 respectively. No growth inhibition observed when culturing contained nitrite nitrogen 0–120 ammonium below 20 mg·L–1....

10.2166/wst.2015.353 article EN Water Science & Technology 2015-07-28

Volumetric oxygen transfer coefficient (KLa) is an important parameter affecting and nitrogen conversion during biological wastewater management. However, how the generation of nitrous oxide (N2O) responds to variation KLa levels unclear. In this study, N2O via main pathway, which was confirmed be nitritation, at different investigated in a partial nitritation-anammox (PN-A) reactor run as sequencing batch reactor. The results showed that PN-A process, described using maximum rate (MGR),...

10.1016/j.jclepro.2021.126104 article EN cc-by Journal of Cleaner Production 2021-01-25
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