A5000348555- HIV/AIDS Research and Interventions
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Impact and Responses
- Pneumocystis jirovecii pneumonia detection and treatment
- Child Nutrition and Water Access
- Herpesvirus Infections and Treatments
- Hepatitis B Virus Studies
- Skin Diseases and Diabetes
- Congenital Anomalies and Fetal Surgery
- Neuroscience of respiration and sleep
- Parvovirus B19 Infection Studies
- Mental Health Treatment and Access
- Hereditary Neurological Disorders
- Iron Metabolism and Disorders
- Long-Term Effects of COVID-19
- Influenza Virus Research Studies
- Malaria Research and Control
- Oral Health Pathology and Treatment
- Peripheral Neuropathies and Disorders
- Otolaryngology and Infectious Diseases
- HIV, Drug Use, Sexual Risk
- Hemoglobinopathies and Related Disorders
Centre Hospitalier Universitaire de Tokoin
2014-2025
University of Lomé
2017-2025
We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 West Africa. included all patients aged 0-24 years on ART from nine clinics Côte d'Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. Baseline varied by clinic was defined as date first DTG prescription; were followed up until database closure/death/loss to follow-up (LTFU, no visit ≥7 months), whichever came first. computed cumulative...
Group Interpersonal Therapy (IPT), an evidence-based treatment of depression recommended by the WHO mhGAP Intervention Guide, was implemented through a task-shifting approach in Senegal, as for depressed people living with HIV (PLWH). Since description resources used and implementation costs incurred is necessary to inform policymakers better, this study aimed estimate associated its implementation. were analyzed using "ingredients-based costing approach" from provider's perspective. We...
Antiretroviral treatment (ART) has been scaled up over the last decade but compared to adults, children living with HIV are less likely receive ART. Moreover, and adolescents more vulnerable than adults virological failure (VF) emergence of drug resistance. In this study we determined outcome in perinatally HIV-1-infected receiving ART Togo.HIV viral load (VL) testing was consecutively proposed all who were on for at least 12 months when attending healthcare services their routine follow-up...
Abstract Introduction We assessed mortality and losses to follow‐up ( LTFU ) during adolescence in routine care settings the International epidemiology Databases Evaluate AIDS (Ie DEA consortium. Methods Cohorts Asia‐Pacific, Caribbean, Central, South America, sub‐Saharan Africa (Central, East, Southern, West) contributed data, included adolescents living with HIV ALHIV enrolled from January 2003 aged 10 19 years (period of adolescence) while under up database closure (June 2016). Follow‐up...
Introduction Access to antiretroviral therapy (ART) is a global priority. However, the attrition across continuum of care for HIV-infected children between their HIV diagnosis and ART initiation not well known. We analyzed time from enrollment into in within International Epidemiology Databases Evaluate AIDS (IeDEA) Global Cohort Consortium. Methods findings included 135,479 HIV-1-infected children, aged 0–19 years ART-naïve at enrollment, 1 January 2004 31 December 2015, IeDEA cohorts...
The prevalence of both type 2 diabetes mellitus (T2DM) and obesity is increasing among people living with HIV (PLHIV) in sub-Saharan Africa. We examined the perceptions management these two conditions PLHIV healthcare workers Côte D'Ivoire. From June to August 2022, we conducted semi-structured face-to-face interviews diagnosed T2DM and/or obesity, as well workers, one major clinics Abidjan, Cote d'Ivoire. explored topics such experiences, acceptability diagnosis PLHIV. Among professional...
Abstract Transition to dolutegravir among 21 167 individuals experienced in antiretroviral therapy West Africa showed heterogeneous timelines and patterns. Initially reported sex disparities tended catch up over time with persisting disparities, according contributing HIV clinics. Key factors facilitating switch were male sex, age <50 years, viral suppression, regimens not based on protease inhibitors.
Sexual and reproductive health issues in adolescents living with HIV (ALHIV) have been left behind care programs. ALHIV are at risk of unintended pregnancy which jeopardizes their socio-economic future, outcomes exposes newborn to transmission. A better understanding these events is needed. We studied the 18-month incidence, explored experiences among female enrolled OPTIMISE-AO cohort, nested prospective paediatric IeDEA cohort Côte d'Ivoire Burkina Faso. conducted a mixed-method study...
Abstract Background Depression is one of the most common psychiatric disorders in people living with HIV (PLHIV). has a negative impact on both mental and physical health mainly associated suboptimal treatment outcomes. To encourage successful aging achievement 3 × 90 objectives older PLHIV, psychological domain must not be neglected. In this context as data are scarce West Africa, study aimed to evaluate prevalence factors severe depressive symptoms PLHIV region world. Methods Data from...
Few data are available on the real-world efficacy of receiving tenofovir-lamivudine-dolutegravir (-DTG) as human immunodeficiencyvirus (HIV) treatment, particularly among young people in West Africa. Here, we evaluated pharmaco-virological outcomes and resistance profiles Togolese children adolescents. A cross-sectional study was conducted Lomé, Togo, enrolling antiretroviral-treated with HIV aged from 18 months to 24 years. Plasma HIV-1 viral load antiretroviral concentrations were...
Abstract Background Nutritional care is not optimally integrated into pediatric HIV in sub-Saharan Africa. We assessed the 6-month effect of a nutritional support provided to children living with HIV, followed multicentric cohort West Methods In 2014-2016, intervention was carried out for aged under 10 years, receiving antiretroviral therapy (ART) or not, five cohorts, Benin, Togo and Côte d’Ivoire. Weight deficiency using two definitions: wasting (Weight Height Z-score [WHZ] children<5...
Malaria is an infectious parasitic disease in the intertropical zone, particularly sub-Saharan Africa, which accounts for 91% of global deaths from this The main objective our work was to describe epidemiological, clinical, therapeutic and evolutionary aspects severe malaria children CHR Tsévié pediatric ward. This a descriptive cross-sectional study with 1 January 31 December 2013. Of 2209 hospitalized 2013, 465 cases or hospital frequency 21.05% were recorded. months June October had many...
We describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 West Africa.
<title>Abstract</title> <bold>Aim:</bold> to estimate the prevalence of sickle cell disease among children and adolescents in pediatric department Sylvanus Olympio University Hospital 2022. <bold>Methods:</bold> this cross-sectional study, all attending study site were proposed participate included if: i) aged between 18 months 19 years, ii) present consultations or hospitalizations iii) provided assent parental informed consent. A 4-5 ml blood sample was collected for hemoglobin...
Guillain-Barré syndrome is rare in children. With polyvalent immunoglobulins the management and prognosis has been significantly improved with complete recovery rate exceeding 80%. We report cases of two children who completely recovered after absence immune globulin. He was a 12 year old daughter an infant 17 months male presented progressive ascending motor deficit, dysphonia difficulty swallowing, breathing, areflexia. A albumino-cytological dissociation found study cerebrospinal fluid...
Abstract Background: Adolescents living with perinatally-acquired HIV (APHIV) face challenges including the disclosure of their HIV-serostatus that we explored in West-African COHADO cohort. We assessed 24-month outcomes among APHIV relation to own HIV-serostatus.Methods: Nested within International epidemiologic Database Evaluate AIDS pediatric West African prospective cohort (IeDEA pWADA), included antiretroviral (ART)-treated aged 10–19 years, enrolled HIV-care <10 Abidjan (Côte...
Background: Birth Asphyxia (BA) is one of the leading causes neonatal death in developing countries. In Togo, 30.55% deaths were related to BA and caused by several risk factors. The purpose this piece work analyse antepartum, intrapartum, foetal factors BA. Methods: This a case control study, conducted from 1st December 2019 28th February 2020 obstetrics wards at intensive care paediatric ward Sylvanus Olympio university teaching hospital (CHU-SO) Lomé, Togo. Neonates diagnosed with (Apgar...
Introduction: in Africa, the proportion of minors with AIDS is ever increasing and adherence to treatment protocols still suboptimal. The study investigated conditions HIV status disclosure patients < 19 two West African cities.
Background: Voluntary testing and counselling rates remain low in Togo. UNAIDS/WHO/CDC have recommended provider-initiated counseling (PITC) for HIV settings with high prevalence since 2007. We aimed to assess the first results of routine Paediatrian units after two years implementation Method: Children (aged<15 years) who visited 20 facilities selected were offered PITC HIV. The intervention was implemented by trained health professionals period spanning. approach piloted between 2012 2014...