A5049440373- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV-related health complications and treatments
- HIV/AIDS drug development and treatment
- HIV, Drug Use, Sexual Risk
- Adolescent Sexual and Reproductive Health
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis C virus research
- HIV/AIDS Impact and Responses
- Global Maternal and Child Health
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Healthcare Systems and Practices
- Viral-associated cancers and disorders
- Cervical Cancer and HPV Research
- Tuberculosis Research and Epidemiology
- Poverty, Education, and Child Welfare
- Family Caregiving in Mental Illness
- Breastfeeding Practices and Influences
- Mental Health Treatment and Access
- Vaccine Coverage and Hesitancy
- Sex work and related issues
- Child Nutrition and Water Access
- Genital Health and Disease
- Reproductive tract infections research
Université de Bordeaux
2016-2025
Inserm
2015-2024
Bordeaux Population Health
2015-2024
Institut de Recherche pour le Développement
2020-2024
Centre Hospitalier Universitaire de Bordeaux
2012-2023
Agence Nationale de Recherches sur le Sida et les Hépatites Virales
2006-2020
Programme PAC-CI
2000-2018
Africa Health Research Institute
2018
Université Paris Cité
2018
Université Félix Houphouët-Boigny
2018
BACKGROUND. The risk of myocardial infarction (MI) in patients with human immunodeficiency virus (HIV) infection has been assessed 13 anti-HIV drugs the Data Collection on Adverse Events Anti-HIV Drugs (D:A:D) study. METHODS. Poisson regression models were adjusted for cardiovascular factors, cohort, calendar year, and use other antiretroviral association between MI cumulative (per year) or recent (current past 6 months) drugs, >30,000 person-years exposure. RESULTS. Over 178,835...
Objective: To compare mortality rates in combination antiretroviral therapy (cART)-treated HIV-infected adults with the general population according to level of CD4 cell count reached and duration exposure cART. Methods: initiating a protease inhibitor-containing treatment between 1997 1999 were selected Agence Nationale de Recherches sur le Sida et les hépatites virales (ANRS) APROCO AQUITAINE cohorts. counts estimated during follow-up using 2-phase mixed linear model. Standardized ratios...
Objective To analyse the early loss of patients to antiretroviral therapy (ART) programmes in resource-limited settings.Methods Using data on 5491 adult starting ART (median age 35 years, 46% female) 15 treatment Africa, Asia and South America with ³ 12 months follow-up, we investigated risk factors for no follow-up after initiation, or death first 6 months.Findings Overall, 211 (3.8%) had 880 (16.0%) were lost 141 (2.6%) known have died months.The probability was higher 2003-2004 than 2000...
Several antiretroviral agents (ARVs) are associated with chronic renal impairment, but the extent of such adverse events among human immunodeficiency virus (HIV)-positive persons initially normal function is unknown.D:A:D study participants an estimated glomerular filtration rate (eGFR) ≥ 90 mL/min after 1 January 2004 were followed until they had a confirmed eGFR ≤ 70 (the threshold below which we hypothesized that interventions may begin to occur) or 60 (a value indicative moderately...
In response to the HIV/AIDS pandemic in sub-Saharan Africa African networks of IeDEA (International epidemiologic databases Evaluate AIDS) aim inform scale-up ART region through clinical and research. Funded by National Institutes Allergy Infectious Diseases (NIAID) objectives across four regions (West Central East Southern Africa) are similar cover all populations including pregnant women infants children adolescents adult patients. They can be summarized as follows: (1) To prove robust...
BackgroundWith the aging of population living with HIV, absolute risk cardiovascular disease (CVD) is increasing. There a need to further facilitate identification persons at elevated in routine practice.
Objective. To compare morbidity and mortality of human immunodeficiency virus type 1 (HIV-1)-infected HIV-1-uninfected children to identify predictors acquired syndrome (AIDS) death among HIV-1-infected in the context a developing country. Design. Prospective cohort study. Setting. Maternal child health clinic Centre Hospitalier de Kigali, Rwanda. Participants. Two hundred eighteen born HIV-1-seropositive mothers 218 seronegative same age parity were enrolled at birth. Outcome Measures....
ABSTRACT There is an urgent need for low-cost human immunodeficiency virus type 1 (HIV-1) viral load (VL) monitoring technologies in resource-limited settings. An automated TaqMan real-time reverse transcription-PCR (RT-PCR) assay was transferred to the laboratory of Centre de Diagnostic et Recherches sur le SIDA, Abidjan, Côte d'Ivoire, and assessed HIV-1 RNA VL testing 806 plasma samples collected within four ANRS research programs. The detection threshold reproducibility were first...
Background: There is a high prevalence of bone demineralization among HIV-infected patients but mechanisms alteration turnover are still unclear and it thought to be multifactorial. Methods: A cross-sectional survey 492 within the Aquitaine cohort estimated osteoporosis/osteopenia investigated associated factors. Bone mineral density total body, lumbar spine femoral neck was measured by dual-energy X-ray absorptiometry. Multivariable analyses association with HIV disease status, treatment...
Aims: To compare the gender distribution of HIV-infected adults receiving highly active antiretroviral treatment (HAART) in resource-constrained settings with estimates HIV infection; to describe clinical characteristics women and men HAART. Methods: The Antiretroviral Therapy Lower-Income Countries, ART-LINC Collaboration is a network clinics providing HAART Africa, Latin America, Asia. We compared UNAIDS data on infection proportions Collaboration. Results: Twenty-nine centers 13 countries...
Comparing mortality rates between patients starting HIV treatment and the general population in four African countries, Matthias Egger colleagues find gap decreases over time, especially with early treatment.
To describe temporal trends in baseline clinical characteristics, initial treatment regimens and monitoring of patients starting antiretroviral therapy (ART) resource-limited settings.We analysed data from 17 ART programmes 12 countries sub-Saharan Africa, South America Asia. Patients aged 16 years or older with documented date start highly active (HAART) were included. Data by calculating medians, interquartile ranges (IQR) percentages regions time periods. Not all centres provided for 2006...