A5101834662- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Cancer, Lipids, and Metabolism
- Energetic Materials and Combustion
- Nutrition, Genetics, and Disease
- Genetic factors in colorectal cancer
- Liver physiology and pathology
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nuclear Receptors and Signaling
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lipid metabolism and disorders
- Ovarian cancer diagnosis and treatment
- Hepatitis B Virus Studies
- Endoplasmic Reticulum Stress and Disease
- Genetic Associations and Epidemiology
- Traditional Chinese Medicine Studies
- Chemical Thermodynamics and Molecular Structure
- Vitamin C and Antioxidants Research
- Thermal and Kinetic Analysis
- Atherosclerosis and Cardiovascular Diseases
- Hepatitis C virus research
University of Michigan
2025
Beijing Chao-Yang Hospital
2021
Capital Medical University
2021
Wenzhou Medical University
2019-2020
First Affiliated Hospital of Wenzhou Medical University
2019-2020
Renji Hospital
2017
Shanghai Jiao Tong University
2017
Qingdao Municipal Hospital
2012
Qingdao University
2012
Abstract Polygenic risk scores (PRS) hold prognostic value for identifying individuals at higher of type 2 diabetes (T2D). However, further characterization is needed to understand the generalizability T2D PRS in diverse populations across various contexts. We characterized a multi-ancestry among 244,637 cases and 637,891 controls eight from Population Architecture Genomics Epidemiology (PAGE) Study 13 additional biobanks cohorts. performance was context dependent, with better those who were...
Alpha-fetoprotein-producing gastric cancer (AFPGC) is associated with high invasion and poor prognosis, but has not been well-documented due to its rarity. To develop the understanding of AFPGC, further facilitate clinical decision-making treatment, we performed clinicopathological molecular characterization AFPGC two major subtypes, namely, adenocarcinoma enteroblastic differentiation (GAED) hepatoid (HAC). The characteristics patients (n = 54) were mainly investigated by...
Several international staging or scoring systems don't accurately predict overall survival (OS) after resection of primary hepatocellular carcinoma (PHCC). Therefore, we attempted to overcome this limitation by constructing the A-index and its associated nomogram.We selected 672 patients who underwent curative PHCC between January 2007 February 2015 at first affiliated hospital Wenzhou medical university. These subjects were randomly divided into training (n = 470) validation group 202)...
Objective To investigate the effect of blueberry anthocyanidin on serum lipid profiles, proinflammatory cytokines and insulin sensitivity in high-fat-diet induced obese rats. Methods Male Sprague-Dawley rats were randomly grouped to receive a standard chow diet(control group, 7 cases) or high-fat-diet(23 cases). Six weeks later, divided into 2 groups.Then, received diet, high-fat-diet, supplemented with extracted from at 200 mg/(kg·d) for 4 weeks, then euthanized.Parameters body...
Objective: MET is a member of the receptor tyrosine kinases. Several MET-targeting inhibitors and antagonistic antibodies have shown promising data in clinical trials lung adenocarcinoma. Finding noninvasive diagnostic tools to estimate status helpful practice. 18 F-fluorodeoxyglucose positron emission tomography/computerized tomography ( F-FDG PET/CT) has been used routinely for diagnosis staging tumors. However, relationship between expression uptake not investigated yet. This study aimed...
Background: Several international staging or scoring systems don't accurately predict overall survival (OS) after radical resection of primary hepatocellular carcinoma (PHCC). Therefore, we attempted to overcome this limitation by constructing a new index (the A-index) and its associated nomogram. Methods: We selected 672 patients who underwent curative PHCC between January 2007 February 2015 at the first affiliated hospital Wenzhou medical university. The subjects were randomly divided into...
Background: Primary hepatocellular carcinoma (PHCC) has a poor prognosis and high short-term mortality rate, even after resection.Thus, early diagnosis in PHCC cases can help improve quality of life via personalized management strategies.Results: The risk score system (RSS) were classified as low (<5 points), medium (5-10 or (>10 points).The areas under the receiver operating characteristic curves 0.80 training cohort 0.69 validation cohort, which indicated satisfactory prognostic...