- Mosquito-borne diseases and control
- Bacterial Infections and Vaccines
- Malaria Research and Control
- Pneumonia and Respiratory Infections
- Viral Infections and Vectors
- Cultural, Media, and Literary Studies
- Heavy Metal Exposure and Toxicity
- Vaccine Coverage and Hesitancy
- Virology and Viral Diseases
- Literature, Culture, and Criticism
- Influenza Virus Research Studies
- Infections and bacterial resistance
- Trace Elements in Health
- COVID-19 epidemiological studies
- Travel-related health issues
- Intramuscular injections and effects
- Lysosomal Storage Disorders Research
- Plant Pathogenic Bacteria Studies
- Immunotherapy and Immune Responses
- Biotechnology and Related Fields
- Zoonotic diseases and public health
- Vector-borne infectious diseases
- vaccines and immunoinformatics approaches
- Congenital Ear and Nasal Anomalies
- Neurological diseases and metabolism
Fundação Oswaldo Cruz
2022-2024
Escola Nacional de Saúde Pública
2024
Secretaria da Saúde
2024
Secretaria Municipal de Saúde
1997-2020
Instituto Agronômico de Pernambuco
2020
Shanghai Public Health Clinical Center
2016
Prefeitura da Cidade do Rio de Janeiro
2016
Universidade Federal do Rio de Janeiro
2001
SUMMARY Zika virus infection was declared a public health emergency of international concern in February 2016 response to the outbreak Brazil and its suspected link with congenital anomalies. In this study, we use notification data disease natural history parameters estimate basic reproduction number ( R 0 ) Rio de Janeiro, Brazil. We also obtain estimates dengue from time series cases outbreaks registered 2002 2012 city, when DENV-3 DENV-4 serotypes, respectively, had just emerged. Our for...
In the last 40 years, Latin America countries, including Brazil, have suffered from emergence and reemergence of arboviruses, first Dengue (DENV) recently Zika (ZIKV) Chikungunya (CHIKV). All three arboviruses are currently endemic in Brazil caused major outbreaks recent years. Rio de Janeiro city, host Summer Olympic Games Football World Cup, has been specially affected by them. A surveillance system based on symptomatic reports is place Rio, but true number individuals unknown due to great...
Dengue has affected Rio de Janeiro City since the 1980s. The sequential Zika and chikungunya virus introductions during 2015 aggravated health scenario, with 97,241 cases of arboviral diseases reported in 2015-2016, some neurological disorders.Arbovirus-related neurologic were descriptively analyzed, including syndromes laboratory results.In total, 112 non-congenital manifestations (Guillain-Barré syndrome, 64.3%; meningoencephalitis, 24.1%; acute demyelinating encephalomyelitis, 8%)...
Abstract This study describes the development of an integrated dengue alert system (InfoDengue), operating initially in city Rio de Janeiro, Brazil. It is a project developed as partnership between academia and municipal health secretariat. At beginning each epidemiological week, captures climate time series, case reporting activity on social network. After data pre-processing, including probabilistic correction notification delay, calculation dengue's effective reproductive number,...
Abstract The present study aimed at evaluating the YF-specific neutralizing antibody profile besides a multiparametric analysis of phenotypic/functional features cell-mediated response elicited by 1/5 fractional dose 17DD-YF vaccine, administered as single subcutaneous injection. immunological parameters each volunteer was monitored two time points, referred as: before (Day 0) [Non-Vaccinated, NV (D0) ] and after vaccination 30–45) [Primary Vaccinees, PV (D30–45) ]. Data demonstrated high...
A randomized, double-blinded study evaluating the immunogenicity, safety and consistency of production a combined diphtheria-tetanus-pertussis-Haemophilus influenzae type b vaccine entirely produced in Brazil by Bio-Manguinhos Instituto Butantan (DTP/Hib-BM) was undertaken. The reference had same DTP but Hib component using purified materials supplied GlaxoSmithKline (DTP/Hib-GSK), which is registered has Brazilian National Immunization Program for over more than five years. One thousand...
This study aimed to determine if immunogenicity measles–mumps–rubella vaccine delivered infants via a disposable-syringe jet injector (DSJI) was non-inferior that administered by needle and syringe (NS). Vaccination safety evaluated, as were the use, performance, acceptability of each delivery method. The DSJI PharmaJet® 2009 generation-1 device (G1) from Bio-Manguinhos. Five hundred eighty-two healthy Brazilian randomized receive G1 or NS. Seroconversion rates against measles mumps viruses...
Meningococcal disease has been a serious public health problem in the city of Rio de Janeiro, with high attack rates among younger children, case fatality rates, and predominance serogroup B. In December 1994 second vaccination drive against B C meningococcal was performed objective protecting children ages 6 months to 13 years. A total 950 thousand received 2 doses vaccine produced by Finlay Institute Cuba. 1995 change observed pattern higher global rate, particularly under 1 year age,...
Na Ilha Cardosa, no sistema lagunar de Maricá-RJ, Brasil, foram realizados levantamentos florísticos, com ênfase para as lenhosas, e diagramas perfil da vegetação dois terrenos adjacentes: um terreno sedimentos arenosos quaternários outro tabuleiro. Em cada área foi marcado transecto 2 x 60m, sendo amostrados todos os indivíduos lenhosos DAS ³ 2,5 cm. Foram 276 herbáceos pertencentes a 69 espécies 33 famílias. Encontrou-se uma diferenciação florística entre duas áreas expressa nos...
OBJETIVO: Avaliar a segurança da vacina combinada de difteria-tétano-coqueluche células inteiras e Haemophilus influenzae tipo b usada no Programa Nacional Imunizações, em especial incidência episódios hipotônicos-hiporresponsivos. MÉTODO: Acompanhamento uma coorte 21.064 lactentes (20.925 ou 99,7% aderiram ao protocolo estudo), nas 48 horas após aplicação difteria, tétano, coqueluche centros saúde na cidade do Rio Janeiro, para determinar investigar eventos adversos graves, espontâneos...
Trata-se de um relato experiencia sobre a implementacao da plataforma web do SIPNI, no municipio Rio Janeiro. A parceria com o Ministerio Saude e Secretaria Estadual possibilitou, forma plena, realizacao deste projeto. Foi uma muito aprendizado que proporcionou mudanca conceito registro em vacinacao, conquistando garantindo adesao dos profissionais das salas experimentaram, partir sua pratica, melhoria na qualidade registros vacinados utilizando nova ferramenta.