A5103236429- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
- Thyroid Cancer Diagnosis and Treatment
- Voice and Speech Disorders
- Cancer, Hypoxia, and Metabolism
- Tracheal and airway disorders
- Cancer Cells and Metastasis
- Circular RNAs in diseases
- TGF-β signaling in diseases
- Cancer-related molecular mechanisms research
- Airway Management and Intubation Techniques
- Sympathectomy and Hyperhidrosis Treatments
- RNA Research and Splicing
- Nitrogen and Sulfur Effects on Brassica
- Metabolism, Diabetes, and Cancer
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Hemostasis and retained surgical items
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Muscle metabolism and nutrition
- Liver Disease and Transplantation
- Medicinal Plant Pharmacodynamics Research
- Peptidase Inhibition and Analysis
- Hepatitis C virus research
- PI3K/AKT/mTOR signaling in cancer
Zhongshan Hospital of Xiamen University
2015-2025
Xiamen University
2008-2023
Southwest Jiaotong University
2023
North Sichuan Medical University
2023
Chengdu Third People's Hospital
2023
Massachusetts General Hospital
2010
Harvard University
2010
University Medical Centre Mannheim
2008
University of Pittsburgh
2008
Heidelberg University
2008
Objective: To evaluate the clinical efficacy and safety of transoral endoscopic thyroidectomy (TOET). Materials Methods: A total 81 patients with thyroid nodules underwent TOET in our department from November 2011 to September 2015. The surgical outcomes, cosmetic results, complications were evaluated. Results: Seventy-nine performed successfully, 2 cases transferred open due intraoperative CO2 embolism. average operation time was 89.0 ± 38.6 minutes, blood loss 29.3 27.6 mL. Two experienced...
Thyroid cancer is one of the most common types in endocrine system. Among all thyroid cancer, papillary carcinoma (PTC) type cancer. Long non‑coding RNA (lncRNA) BRAF‑activated non‑protein‑coding (BANCR) a 688‑bp‑long nucleotide transcript, which was first identified melanoma. The function BANCR remains unclear. aim present study to investigate whether involved development results indicated that expression increased tumors compared with adjacent normal tissues. cell lines, level differed:...
With the increasing incidence of thyroid cancer worldwide and demand for surgery, risk parathyroid injury is also increasing, which will lead to postoperative hypoparathyroidism (HP) hypocalcemia. In order improve quality life patients after there an urgent need develop a novel platform that can identify gland immediately during surgery. The promotes increase blood calcium concentration by secreting hormone (PTH). Therefore, in this study, we used sensitive surface-enhanced Raman...
Abstract Objective We had previously reported endoscopic central and lateral neck dissection via breast combined with an oral approach for papillary thyroid cancer treatment. In this study, we optimized the procedure Wu’s seven steps to make quicker easier. Methods are: (1) establish working space, (2) isolate sternocleidomastoid internal jugular vein, (3) dissect approach, (4) lymph nodes (5) inferior board of level IV (6) remove tissues levels IV, III, II (7) wash space place drainage...
Abstract Backgrounds Gastric cancer (GC) is general disease in human digestive system with malignancy. Emerging findings indicated that hsa_circ_0031452 (circHECTD1) was strictly associated carcinogenesis. Nevertheless, the role of circHECTD1 drug-resistance still needed to be explained. Methods Quantitative real-time polymerase chain reaction (qRT-PCR) employed examine expression profiles circHECTD1, microRNA (miR)-137, and pre-leukemia transcription factor 3 (PBX3). The function...
To evaluate the preventive effects of phosphorus-32 glass microspheres (P32-GMS) in recurrence massive hepatocellular carcinomas (HCCs) after tumor resection. Twenty-nine patients with HCCs received local P32-GMS implantation liver tumors were removed, while other 38 not treated hepatectomies. The radioactivity blood, urine and examined. complications, HCC overall survival rates analyzed. implanted did cause systemic absorption P32. There no significant differences postoperative...
Purpose: Transoral endoscopic thyroidectomy via vestibular approach (TOETVA), with its excellent cosmetic effect, has become increasingly popular worldwide. Nonetheless, anatomic obstacles have limited development to a certain extent. Here, we present our preliminary outcomes of transoral submental and (TOETSMVA), which can overcome those limitations. Methods: From November 2019 March 2020, performed TOETSMVA in 21 consecutive patients thyroid carcinoma at Zhongshan Hospital, Xiamen...
From July 2020 to March 2022, 3 patients with papillary thyroid cancer (PTC) and microgenia underwent transoral endoscopic surgery via a vestibular approach or lateral neck dissection the breast approaches chin silastic augmentation genioplasty performed concurrently. Image documentation, patient satisfaction, complications other factors such as demographics clinicopathologic details were recorded. None of developed major there no infection displacement implant. All satisfied cosmetic...
This study aimed to explore the clinical implications of katanin P60 and P80 (katanin P60/P80) regarding their correlations with clinicopathological features survival profiles in papillary thyroid carcinoma (PTC) patients.Tumor tissue paired adjacent specimens were obtained from 172 PTC patients who underwent lobectomy or thyroidectomy. Besides, immunohistochemistry assay immunoreactive (IR) score (multiplying staining intensity by density score) used determine P60/P80 expressions. According...
Cachexia (CAC) is a debilitating metabolic syndrome. Although dietary interventions are attractive, long-term adherence to specific diets difficult maintain and can lead systemic side effects. Ethyl 3-hydroxybutyrate (EHB) commonly used food additive found in wine Tribolium castaneum. In this study, we investigated the effects of EHB administration cachectic mice. After single intraperitoneal injection into mice, (3-HB) levels were significantly increased serum gastrocnemius The alleviated...
Background Intraoperative neurological monitoring is important in locating and assessing nerves during surgery. This study aimed to investigate the feasibility of neural ultrasound-guided radiofrequency ablation (RFA) thyroid nodules.Methods From February 2019 August 2019, 16 patients (age, 42.8 ± 15.9 years; range, 17–74 years) with benign nodules who underwent RFA Zhongshan Hospital, Xiamen University, were included. A neuromonitoring system stimulated vagus nerve obtain electromyographic...
Transoral endoscopic approaches for thyroidectomy (TOET) have been developing since 2008. To date, single centers gained great experience and patients treated worldwide (477 by February 2016) resulted in complication rates [transient recurrent laryngeal nerve palsy (RLNP) 2.5%, permanent RLNP 0.4%, transient mental paraesthesia 5.9%, local or neck site infections 1.2%] comparable to conventional open other robotic approaches. The conversion rate from TOET surgery is very low (0.6%). This...
Objective To evaluate the outcomes of totally transoral video-assisted thyroidectomy.Methods Clinical data 37 cases thyroidectomy from November 2011 to April 2013 at Zhongshan Hospital,Xiamen University were analyzed retrospectively.Results All underwent successfully with a mean operation time 109.5 min,blood loss 15-60 ml,the postoperative hospital-stay was 3.5 days.The complications included infection in three cases,nasal congestion one case,transient dysosphresia case.All subject...
OBJECTIVE To elucidate the association of TNF-alpha-308G/A gene functional polymorphism with development and progression colorectal cancer. METHODS PCR-RFLP was employed to detect TNF-alpha-308 G/A genotypes in 157 cancer patients 117 healthy controls. RESULTS The frequency genotype allele were not significantly different between controls (genotype chi(2)=1.054, P=0.591, chi(2)=0.404, P=0.525). A/A A III+IV stage (62 total) higher than those I+II stages (85 (A allele: 22.6% vs 12.9%,...