A5043453587- Acute Myeloid Leukemia Research
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Lymphoma Diagnosis and Treatment
- Multiple Myeloma Research and Treatments
- Acute Lymphoblastic Leukemia research
- Chronic Lymphocytic Leukemia Research
- Erythrocyte Function and Pathophysiology
- Cutaneous lymphoproliferative disorders research
- Erythropoietin and Anemia Treatment
- Hematological disorders and diagnostics
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders Research
- Pancreatic function and diabetes
- Infant Nutrition and Health
- Protein Degradation and Inhibitors
- Blood disorders and treatments
- Fungal Plant Pathogen Control
- Phytochemistry and biological activities of Ficus species
- Peptidase Inhibition and Analysis
- Chronic Myeloid Leukemia Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Neonatal Health and Biochemistry
- Platelet Disorders and Treatments
Post Graduate Institute of Medical Education and Research
2016-2025
Hudson Institute
2021
John Wiley & Sons (United States)
2021
All India Institute of Medical Sciences
2015
Abstract Trephine bone marrow biopsy is an effective technique for diagnosing hematological malignancies in patients of different ages. During trephine biopsy, cores are obtained detailed morphological evaluation to look any abnormality and arrive at a diagnosis. The primary goal this work perform survey on Indian various ages the process. In present study, data related 274 samples from 300 were acquired Post Graduate Institute Medical Education Research (PGIMER) Chandigarh, India. Pain was...
CASE A 10-year-old girl presented with fever for 15 days, cough and rapid breathing 12 days abdominal pain 6 days. The was high grade (peaking at 40 °C), accompanied by chills rigors, occurring twice or thrice each day. Three after the onset of fever, she developed a dry and, soon thereafter, breathlessness. She diagnosed pneumonia local hospital received oxygen therapy, intravenous antibiotics supportive care. About week illness, complained intermittent, diffuse unrelated to meals not...
Background: Post-renal transplant anemia significantly impacts patient outcomes and quality of life. The only option available until recently was erythropoietin (EPO) that requires intravenous or subcutaneous injection. New class drugs are Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor (HIF PHI) have become there is scarce data on their use in kidney recipients (KTRs). Methods: This prospective observational study which included 58 renal with (Hb < 10 g/dL) who were started either...
To evaluate the spectrum of genetic defects in Indian patients with unexplained erythrocytosis.Fifteen families (18 patients) erythrocytosis were enrolled after excluding polycythemia vera and secondary erythrocytosis. Focused Sanger sequencing from genomic DNA was performed for EPOR (exon 8), VHL (exons 2-3), EGLN1 2-5), EPAS1 12), all exons HBB, HBA1, HBA2 genes.Eleven 18 (including two pairs brothers) had Chuvash polycythemia, that is, homozygosity VHL:c.598C > T (p.Arg200Trp). Three (two...
Nutritional anemia i.e. iron deficiency and CKD are prevalent in developing countries. patient population has poor tolerance to oral as compared healthy individuals thus inadequate response iron. This leads complications like gastrointestinal side effects. Studies have shown that adding Lactoferrin treatment improves pregnant women patients with malignancy. Data on efficacy of this drug the is scarce.
Anemia continues to be a common complication in chronic kidney disease (CKD) population despite optimum treatment with adequate dialysis, erythropoietin and repletion of nutrient deficiencies. As shown via our other abstract presented at WCN 2024, lactoferrin has antiinflammatory properties plays major role improvement hemoglobin, absorption utilization iron. Erythroferrone is hormone that increased as the body's response anemia improves hemoglobin (Hb) levels. Among mechanisms for improving...
Abstract Introduction Flow cytometry‐based paroxysmal nocturnal hemoglobinuria (PNH) testing involves utilization of monoclonal antibodies against GPI‐linked proteins and FLAER. The ability FLAER to bind a wide variety structures be utilized across different leukocyte subsets is remarkable. We hypothesize that as standalone reagent may equally effective for detecting PNH clones. present study intends compare the results alone‐based strategy recommended FLAER+GPI‐linked protein‐based approach...
Abstract Common pediatric malignancies often surprise clinicians with unusual presentations. In this narrative, we report two patients common childhood cancer having unique neuroophthalmic characteristics. the first case, have a child solid tumor presenting blindness without proptosis, while second case is of hematological malignancy unilateral proptosis visual impairment. The highlights that cancers may present symptoms on rare occasions, creating diagnostic conundrum.
Abstract Acute lymphoblastic leukemias (ALLs) are hematological neoplasms characterized by clonal proliferation of lymphoid blasts, which can be B- or T-cell type. Flow cytometric immunophenotyping is an integral component in establishing blast lineage during the diagnostic workup ALLs, aiding appropriate therapy, prognostication, and monitoring disease. The current review focuses on utility flow cytometry including usefulness various antibodies pitfalls diagnosis.
According to population-based studies, the epidemiology of chronic kidney disease (CKD) varies by sex and affects more women than men, particularly in case CKD. Very less is known about how gender-based social inequalities may impact CKD patients' ability access care its outcome. Although there are with worldwide, but only 40% patients on dialysis female. Our goal was outline viewpoints regarding gender differences outcomes care.
Anemia is one of the most common complications chronic kidney disease (CKD) and associated with other like increased hospitalization requirement blood transfusion, decreased quality life, etc. Despite standard care adequate dialysis, many patients continue to be anemic it also affects their peri-operative outcomes during after renal transplantation. Literature review shows that Lactoferrin useful in treating anemia pregnant woman malignancy.