A5089155218- Cardiovascular Disease and Adiposity
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Radiomics and Machine Learning in Medical Imaging
- Coronary Interventions and Diagnostics
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac Structural Anomalies and Repair
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Aortic Disease and Treatment Approaches
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrhythmias and Treatments
- Advanced X-ray and CT Imaging
- Cardiac pacing and defibrillation studies
- Medical Imaging Techniques and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer, Lipids, and Metabolism
- Aortic aneurysm repair treatments
- Systemic Lupus Erythematosus Research
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Circular RNAs in diseases
Universidade do Porto
2015-2024
Royal Brompton Hospital
2022-2024
Centro Hospitalar de Vila Nova de Gaia
2014-2024
Thomas Foundation
2024
Weatherford College
2024
King's College London
2023-2024
South West London and St George's Mental Health NHS Trust
2023
St George’s University Hospitals NHS Foundation Trust
2023
United Nations Industrial Development Organization
2023
Guy's and St Thomas' NHS Foundation Trust
2021-2022
Coronary artery inflammation inhibits adipogenesis in adjacent perivascular fat. A novel imaging biomarker-the fat attenuation index (FAI)-captures coronary by mapping spatial changes of on computed tomography angiography (CTA). However, the ability FAI to predict clinical outcomes is unknown.In Cardiovascular RISk Prediction using Computed Tomography (CRISP-CT) study, we did a post-hoc analysis outcome data gathered prospectively from two independent cohorts consecutive patients undergoing...
Psoriasis is a chronic inflammatory skin disease associated with increased coronary plaque burden and cardiovascular events. Biologic therapy for psoriasis has been found to be favorably luminal plaque, but it unclear whether these associations are attributable direct anti-inflammatory effects on the arteries.To investigate association of biologic inflammation in patients using perivascular fat attenuation index (FAI), novel imaging biomarker that assesses by mapping spatial changes...
Several deep‐learning models have been proposed to shorten MRI scan time. Prior that utilize real‐valued kernels limited capability learn rich representations of complex data. In this work, we a complex‐valued convolutional network ( ℂ Net ) for fast reconstruction highly under‐sampled data and evaluate its ability rapidly reconstruct 3D late gadolinium enhancement (LGE) preserves the nature optimal combination real imaginary components throughout process by utilizing convolution, novel...
Purpose To investigate reproducibility of myocardial radiomic features with cardiac MRI. Materials and Methods Test-retest studies were performed a 3-T MRI system using commonly used sequences cine balanced steady-state free precession (cine bSSFP), T1-weighted T2-weighted imaging, quantitative T1 T2 mapping in phantom experiments 10 healthy participants (mean ± standard deviation age, 29 years 13). In addition, this study assessed repeatability 51 patients (56 14) who underwent imaging...
Background In patients with suspected or known hypertrophic cardiomyopathy (HCM), late gadolinium enhancement (LGE) provides diagnostic and prognostic value. However, contraindications long‐term retention of have raised concern about repeated administration in this population. Alternatively, native T 1 ‐mapping enables identification focal fibrosis, the substrate LGE. However HCM‐specific heterogeneous fibrosis distribution leads to subtle ‐maps changes that are difficult identify. Purpose...
Cardiovascular magnetic resonance (CMR) with late-gadolinium enhancement (LGE) is increasingly being used in hypertrophic cardiomyopathy (HCM) for diagnosis, risk stratification, and monitoring. However, recent data demonstrating brain gadolinium deposits have raised safety concerns. We developed validated a machine-learning (ML) method that incorporates features extracted from cine to identify HCM patients without fibrosis whom can be avoided.An XGBoost ML model was using regional wall...
Background Cardiac magnetic resonance (MR) images are often collected with different imaging parameters, which may impact the calculated values of myocardial radiomic features. Purpose To investigate sensitivity features to changes in parameters cardiac MR images. Study Type Prospective. Population A total 11 healthy participants/five patients. Field Strength/ Sequence 3 T/cine balanced steady‐state free‐precession, T 1 ‐weighted spoiled gradient‐echo, 2 turbo spin‐echo, and quantitative...
Previous studies showed that metabolic syndrome is associated with aortic valve calcification (AVC) and poor outcomes in stenosis (AS). However, if these associations change how body fat impacts the prognosis of patients late stage disease have been not yet explored. To determine association mass index (BMI) visceral AVC mortality after transcatheter replacement (TAVR). This was a prospective cohort 170 severe AS referred to TAVR. We quantified score depots including epicardial adipose...
The impact of coronary artery disease (CAD) on outcomes after transcatheter aortic valve implantation (TAVI) has not been clarified. Furthermore, less is known about the indication and strategy revascularization in these high risk patients.This study sought to determine prevalence prognostic CAD patients undergoing TAVI, assess safety feasibility percutaneous intervention (PCI) before TAVI.Patients with severe stenosis (AS) TAVI were included into a prospective single center registry from...
Myocarditis is assumed to involve both ventricles equally. Right ventricular predominant involvement rarely described. A case of acute viral right myocarditis presenting with chest pain and syncope, grade 3 atrioventricular block, dilatation free wall hypokinesia reported. Cardiac MRI showed late enhancement the without left ventricle. Anti-Coxsackie A9 virus neutralising IgM-type antibodies titre was elevated. This emphasises that manifestations can be limited ventricle should considered in...
Postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG) has been associated with increased risk of death in women but not men. We aimed to explore predictors and long-term mortality POAF following isolated aortic valve replacement (AVR) surgery men women.This study included 379 severe stenosis patients no prior (AF) who underwent AVR surgery. used multiple logistic regression investigate independent gender-specific new-onset POAF, we performed Kaplan-Meier (KM)...